Genes News and Research

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UCLA-developed nanospears could make gene therapies safer, faster and more cost-effective

UCLA scientists have developed a new method that utilizes microscopic splinter-like structures called "nanospears" for the targeted delivery of biomolecules such as genes straight to patient cells. These magnetically guided nanostructures could enable gene therapies that are safer, faster and more cost-effective.

15 Mar 2018

Leicester research could help identify people with asthma of different severities

A team of researchers from the NIHR Leicester Biomedical Research Centre – a partnership between Leicester’s Hospitals, the University of Leicester and Loughborough University - has identified biological variations in lung tissue samples that for the first time can help identify people with mild asthma from those with moderate or severe asthma.

15 Mar 2018

Researchers identify novel gene involved in familial breast cancer

An international research consortium led by Dr Jordi Surrallés, director of the Genetics Service at the Hospital de Sant Pau and professor of Genetics at the UAB, and by Dr Miquel Àngel Pujana, director of the ProCURE Research Programme of the Catalan Institute of Oncology, has identified a novel gene involved in this type of cancer, known as EDC4.

14 Mar 2018

NIH researchers explore genetic clocks to understand role of aging in neurodegeneration

To understand the link between aging and neurodegenerative disorders such as Alzheimer's disease, NIH scientists compared the genetic clocks that tick during the lives of normal and mutant flies.

14 Mar 2018

Genetic counseling missed by some breast cancer patients, study finds

As new genes are linked to breast cancer occurring in families and as genetic testing becomes more important in directing treatment for newly diagnosed patients, a substantial number of those at the highest risk are not getting tested.

14 Mar 2018

Study highlights divergent molecular mechanisms contributing to depression in men and women

Men and women with major depressive disorder have opposite changes in the expression of the same genes, according to a new postmortem brain study by researchers at the University of Pittsburgh and Centre for Addiction and Mental Health, Toronto, Canada.

14 Mar 2018

New findings yield insights into factors that contribute to aggressive endometrial tumors

New research from Huntsman Cancer Institute at the University of Utah indicates steroid and hormone receptors are simultaneously active in many endometrial cancer tissues.

13 Mar 2018

Genetic heart mutations account for fewer sudden and unexplained infant deaths

Researchers have discovered that heart disease caused by genetic mutations account for significantly fewer sudden and unexplained deaths of infants than previously reported.

13 Mar 2018

Researchers create cardiomyocyte molds to mend broken hearts

2.5 billion. That's approximately the number of times the human heart beats in 70 years. And sometimes during the course of its unrelenting contractions and relaxations, the heart muscle can no longer bear the strain.

13 Mar 2018

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

NIH-funded researchers at Stanford University used the gene editing tool CRISPR-Cas9 to rapidly identify genes in the human genome that might modify the severity of amyotrophic lateral sclerosis and frontotemporal dementia caused by mutations in a gene called C9orf72.

13 Mar 2018

Large number of genes associated with intelligence discovered

A large genome study by researchers at the University of Edinburgh and Harvard University has found over 500 genes that can be attributed to intelligence. The study was published in the latest issue of the journal Molecular Psychiatry.

13 Mar 2018

Genetic link to insomnia found

A new study has found certain genes that predispose a person to develop insomnia or sleep problems. This was one of the largest genome wide studies undertaken on insomnia. The study led by psychiatrist Murray Stein from the University of California San Diego was published in the latest issue of the journal Molecular Psychiatry.

13 Mar 2018

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Tracking the growth and migration of cells under hypoxic conditions in vitro can be challenging because measurements must be made in a manner that does not perturb the atmospheric composition of the closed system.

13 Mar 2018

International research consortium identifies 22 new genetic risk factors for stroke

An international research consortium studying 520,000 individuals from around the world has identified 22 new genetic risk factors for stroke, thus tripling the number of gene regions known to affect stroke risk.

13 Mar 2018

Scientists link 110 genes to increased risk of breast cancer

Scientists have linked 110 genes to an increased risk of breast cancer in the most comprehensive study ever to unpick the genetics of the disease.

13 Mar 2018

Study identifies gene that influences risk of obesity in adulthood

The importance of good nutrition in the early development of children has been recognized for many decades. Nutritional experiences in early life can have profound and long-lasting effects on body weight in later life.

13 Mar 2018

Study highlights potential of ASO therapy to treat Fuchs endothelial corneal dystrophy patients

A proof-of-concept study carried out at UCL Institute of Ophthalmology with funding from Fight for Sight has highlighted the potential of a targeted antisense oligonucleotide therapy to treat Fuchs endothelial corneal dystrophy patients with a mutation in the TCF4 gene.

12 Mar 2018

We may be genetically wired to be empathic finds study

According to a new study, the level of empathy we display may not be a result of our experiences and upbringing alone but also genetic. Researchers from Cambridge studied and made this novel discovery that appeared in the latest issue of the journal Translational Psychiatry.

12 Mar 2018

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Pancreatic cancer is one of the less common but deadliest cancers. Modified oncolytic adenoviruses represent an alternative to chemotherapy and targeted therapies, which have a high mortality rate.

9 Mar 2018

Scientists uncover detailed map of the brain circuits behind thirst and satiety

Scientists uncovered a high-resolution map of the wiring inside the mouse brain's thirst center. With these blueprints, they could trick mice into becoming light or heavy water drinkers.

8 Mar 2018

Genes News and Research

UCLA-developed nanospears could make gene therapies safer, faster and more cost-effective

Leicester research could help identify people with asthma of different severities

Researchers identify novel gene involved in familial breast cancer

NIH researchers explore genetic clocks to understand role of aging in neurodegeneration

Genetic counseling missed by some breast cancer patients, study finds

Study highlights divergent molecular mechanisms contributing to depression in men and women

New findings yield insights into factors that contribute to aggressive endometrial tumors

Genetic heart mutations account for fewer sudden and unexplained infant deaths

Researchers create cardiomyocyte molds to mend broken hearts

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

Large number of genes associated with intelligence discovered

Genetic link to insomnia found

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

International research consortium identifies 22 new genetic risk factors for stroke

Scientists link 110 genes to increased risk of breast cancer

Study identifies gene that influences risk of obesity in adulthood

Study highlights potential of ASO therapy to treat Fuchs endothelial corneal dystrophy patients

We may be genetically wired to be empathic finds study

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Scientists uncover detailed map of the brain circuits behind thirst and satiety

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