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Elusys’ Anthim BLA to treat inhalational anthrax accepted for review by the FDA

Elusys Therapeutics, Inc. today announced the U.S. Food and Drug Administration has accepted for filing and review its Biologics License Application for Anthim® (obiltoxaximab) for the treatment and prevention of inhalational anthrax, a top bioterror threat which was submitted on March 20, 2015. Anthim is a candidate for future acquisition into the Strategic National Stockpile, the U.S. government's repository of critical medical supplies for biowarfare preparedness.

2 Jun 2015

$Matched therapy and FoundationOne genomic profiling improve outcomes in patients with refractory cancer$

Matched therapy and FoundationOne genomic profiling improve outcomes in patients with refractory cancer

Foundation Medicine, Inc. and collaborators from the University of Texas MD Anderson Cancer Center and Sarah Cannon Research Institute at HealthOne today announced compelling new data demonstrating that matching patients to targeted therapies based on the unique molecular profile of the patient’s advanced cancer leads to improved outcomes across a variety of key measures, including overall survival.

2 Jun 2015

GSF's financial support helps seven million people become open-defecation free

The GSF's latest Progress Report details how its financial support for nationally-led programmes has helped seven million people in over 20,500 communities become open-defecation free, improved toilets for 4.2 million people and seen eight million people gain access to hand-washing facilities.

2 Jun 2015

Using earlier surgical intervention more beneficial to patient with degenerative mitral valve disease

A more aggressive approach to treating degenerative mitral valve disease, using earlier surgical intervention and less invasive techniques, is more beneficial to the patient than "watchful waiting," according to an article in the June 2015 issue of The Annals of Thoracic Surgery.

2 Jun 2015

Heart-healthy diet may benefit men after prostate cancer diagnosis

After a prostate cancer diagnosis, eating a diet higher in red and processed meat, high-fat dairy foods, and refined grains--known as a Western diet--may lead to a significantly higher risk of both prostate cancer-related mortality and overall mortality compared with eating a diet rich in vegetables, fruits, fish, whole grains, and healthy oils, according to a new study from Harvard T.H. Chan School of Public Health.

1 Jun 2015

Innovative mini hybrid gamma ray camera improves removal of tumours and lymph nodes

Universities of Leicester and Nottingham to develop mini hybrid gamma ray camera to revolutionise identification and removal of tumours and lymph nodes

1 Jun 2015

RI-MUHC researchers receive innovations grants to build technologies to address cancer challenges

"Thanks to the Innovation Fund, our donors to the MGH Foundation and the vision of the Max Pacioretty Foundation, this new specialized MRI will place the Montreal General Hospital as one of the leading level 1 trauma centres in Canada. This valuable piece of healthcare technology will also allow our world-class researchers to better understand brain injuries, which will lead to improved patient diagnosis and treatment," adds Jean-Guy Gourdeau, President and Chief Executive Officer of the Montreal General Hospital Foundation at the MUHC.

1 Jun 2015

Premature mortality target highly unethical and explicitly ageist

One of the main health targets proposed by the UN Sustainable Development Goals (SDG) is to reduce by one-third premature mortality from non-communicable diseases such as cancer, stroke and dementia. The goals for 2016-2030 define premature mortality as deaths occurring among people aged 69 years old or younger.

1 Jun 2015

Statins reduce risk of death by 67% in CABG surgery

Research presented at this year's Euroanaesthesia exploring the protective effect of various heart medications that patients are taking before undergoing coronary artery bypass graft (CABG) surgery concludes that statins reduce the risk of death by two thirds, or 67 percent, while no consistent effects were seen for other medications.

1 Jun 2015

Lancet Diabetes & Endocrinology to publish paper on eGFR and albuminuria for prediction of cardiovascular outcomes

The Lancet Diabetes & Endocrinology is pleased to announce that the following paper will be published to coincide with presentation at the 52nd ERA-EDTA Congress, taking place in London, UK, May 28 - 31, 2015.

1 Jun 2015

Modified cold sore (herpes) virus improves survival in stage IIIb to IV melanoma patients

It's a new weapon in the arsenal of cancer fighting treatments: utilizing genetically modified viruses to invade cancer cells and destroy them from the inside.

1 Jun 2015

Updated data from PROCLAIM national patient registry presented at 51st ASCO

Prometheus Laboratories, Inc. announced today the presentation of updated data from the PROCLAIM national patient registry in which first-line Proleukin® (aldesleukin for injection) therapy improved survival in patients with metastatic renal cell carcinoma (mRCC), compared to patients previously treated with targeted therapies.

1 Jun 2015

Astute Medical's NephroCheck Test obtains measurements of two biomarkers that act as alarm for AKI risk

An intervention known as remote ischemic preconditioning (RIPC) significantly reduced the occurrence of acute kidney injury (AKI) in cardiac surgery patients and confirmed that post-operative elevations of two kidney biomarkers act as an alarm for risk of AKI, according to a study published online today in the Journal of the American Medical Association.

30 May 2015

Modified herpes virus improves survival in melanoma patients

University of Louisville researcher Jason Chesney, M.D., Ph.D., deputy director of the James Graham Brown Cancer Center, and a team of international scientists found that stage IIIb to IV melanoma patients treated with a modified cold sore (herpes) virus had improved survival.

30 May 2015

21st century trends in management of small renal cancers

A US population-based cohort study reveals a change in the management of small renal masses in the 21st century with rates of nephron-sparing surgery on the rise and a corresponding decrease in the use of radical nephrectomy.

29 May 2015

Pulmonary rehabilitation ‘should include sleep assessment’

Researchers say that pulmonary rehabilitation programmes for patients with moderate to severe chronic obstructive pulmonary disease should include sleep assessment.

29 May 2015

Tackling comorbidities could improve MS survival

Survival of patients with multiple sclerosis is still reduced, despite recent improvements, say researchers.

28 May 2015

Study explores accuracy of body weight perception and obesity in Chinese Americans

Worldwide, obesity is becoming more prevalent. According to The World Health Organization, worldwide obesity has nearly doubled since 1980, and in 2008 25% of adults aged 20 and over were overweight, and another 11% were obese. Obesity has been identified as a major source of unsustainable health costs and numerous adverse outcomes, including morbidity and mortality due to hypertension, type 2 diabetes, cardiovascular diseases and certain types of cancer.

28 May 2015

GOLD 2007 and 2011 fail to accurately predict mortality risk

Neither the 2007 nor the 2011 Global Initiative for Chronic Obstructive Lung Disease classification systems have sufficient prognostic accuracy to predict mortality, a pooled analysis of individual patient data shows.

27 May 2015

Actavis creates collaborative program to improve care for patients with multidrug-resistant infections

Actavis plc, a leading global specialty pharmaceutical company committed to infectious disease treatment innovation, today announced the creation of SHARE ID (Sharing Hospital data to Advance Research and Enhance patient care in Infectious Diseases), a collaborative program to leverage real-world data to advance the delivery and effectiveness of care for patients with serious infections due to antibiotic-resistant pathogens.

27 May 2015

Mortality News and Research

Elusys’ Anthim BLA to treat inhalational anthrax accepted for review by the FDA

Matched therapy and FoundationOne genomic profiling improve outcomes in patients with refractory cancer

GSF's financial support helps seven million people become open-defecation free

Using earlier surgical intervention more beneficial to patient with degenerative mitral valve disease

Heart-healthy diet may benefit men after prostate cancer diagnosis

Innovative mini hybrid gamma ray camera improves removal of tumours and lymph nodes

RI-MUHC researchers receive innovations grants to build technologies to address cancer challenges

Premature mortality target highly unethical and explicitly ageist

Statins reduce risk of death by 67% in CABG surgery

Lancet Diabetes & Endocrinology to publish paper on eGFR and albuminuria for prediction of cardiovascular outcomes

Modified cold sore (herpes) virus improves survival in stage IIIb to IV melanoma patients

Updated data from PROCLAIM national patient registry presented at 51st ASCO

Astute Medical's NephroCheck Test obtains measurements of two biomarkers that act as alarm for AKI risk

Modified herpes virus improves survival in melanoma patients

21st century trends in management of small renal cancers

Pulmonary rehabilitation ‘should include sleep assessment’

Tackling comorbidities could improve MS survival

Study explores accuracy of body weight perception and obesity in Chinese Americans

GOLD 2007 and 2011 fail to accurately predict mortality risk

Actavis creates collaborative program to improve care for patients with multidrug-resistant infections

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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