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Early-in-life antibiotic exposure increases susceptibility to inflammatory bowel disease

Even short, single antibiotic courses given to young animals can predispose them to inflammatory bowel disease (IBD) when they are older, according to Rutgers researchers.

29 Jul 2020

Study shows promise of a major breakthrough in healing chronic diabetic ulcers

A new study released today in STEM CELLS Translational Medicine shows promise of a major breakthrough in healing chronic foot ulcers resulting from diabetes.

28 Jul 2020

UT Southwestern Medical Center ranks among the top 50 hospitals

UT Southwestern Medical Center is the No. 1 hospital in Dallas-Fort Worth – the nation's fourth-largest metro area – and ranks among the top 50 hospitals nationally in 10 specialties ranging from brain to heart care, according to U.S. News & World Report's annual Best Hospitals report released today. Six of the specialties rank in the top 25.

28 Jul 2020

Finding the right treatment for people with IBD may soon become easier

Finding the right treatment for people living with chronic intestinal inflammation, also known as inflammatory bowel disease, might soon be getting easier.

27 Jul 2020

An important SARS-CoV-2 enzyme is responsible for low in vivo antiviral efficacy of hydroxychloroquine

Researchers have shown that hydroxychloroquine interferes with only one redundant pathway that activates the SARS-CoV-2 spike protein.

24 Jul 2020

ASCRS releases updated recommendations for surgery in patients with Crohn's disease

Although rates of surgery for Crohn's disease have decreased over the years, many patients still require surgical treatment - due to inadequate responses to medical therapy, severe attacks of acute colitis, and many other situations.

23 Jul 2020

Study may lead to more effective treatments for chronic intestinal inflammation

Finding the right treatment for people living with chronic intestinal inflammation, also known as inflammatory bowel disease (IBD), might soon be getting easier. World IBD Day happens on 19 May each year, with the goal to raise awareness about the disease and urge action.

23 Jul 2020

Study shows interferons do not induce the expression of SARS-CoV-2 cell entry receptor

In a new bioRxiv study, authors identified a isoform of ACE2 (designated as deltaACE2 or dACE2) receptor, shown to be induced in various human cell types.

23 Jul 2020

Silver-plated gold nanostars could be used to identify early biomarkers of cancer

Biomedical engineers at Duke University have engineered a method for simultaneously detecting the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification.

21 Jul 2020

Chronic inflammation associated with IBD disrupts tissue structure of the colon, study finds

In a new study, researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased risk of colorectal cancers, at a molecular level.

21 Jul 2020

Mortality rates for complex cancer procedures vary based on hospital ratings

A new paper in the JNCI Cancer Spectrum, published by Oxford University Press, finds that the mortality rates for complex cancer procedures differ greatly between one-star hospitals (10.4%) and five-star hospitals (6.4%).

14 Jul 2020

Upcoming phase II study to discover personalized therapy for patients at high risk for breast cancer relapse

Indiana University School of Medicine researchers Milan Radovich, PhD, and Bryan Schneider, MD, have discovered that the presence of circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) in the plasma of women's blood who have undergone chemotherapy prior to surgery for the treatment of stage 1, 2 or 3 triple negative breast cancer are critical indicators for the prediction of disease recurrence and disease-free survival.

10 Jul 2020

Aspirin and flavonoids in fruits and vegetables could help prevent colorectal cancer

A diet rich in fruits and vegetables and a daily dose of aspirin have one thing in common - both can help prevent colorectal cancer. Yet scientists have struggled for decades to find the source of their ability to inhibit cancer cell growth.

7 Jul 2020

Corn-based diet with flavonoids alleviates IBD-like symptoms in mice

Flavonoids from a specific line of corn act as anti-inflammatory agents in the guts of mice with an inflammatory-bowel-disease-like condition, according to a team of researchers who said flavonoid-rich corn should be studied to determine its potential to provide a protective effect on human health.

7 Jul 2020

Study explores the role of gut Piezo1 in sensing of bacterial RNA

In a new study published in Cell, "RNA sensing by gut Piezo1 is essential for systemic serotonin synthesis", a research team led by Kenta Maruyama M.D., Ph.D. from National Institute for Physiological Sciences explored the role of Piezo1, a mechano-sensing receptor, in the sensing of bacterial RNA.

7 Jul 2020

Surgical delay linked to increased risk in gastrointestinal malignancies, study finds

Early in the COVID-19 pandemic, widespread cancellations of electively-scheduled or "non-emergency" operations were implemented to free up hospital beds and conserve protective equipment for health care workers.

7 Jul 2020

Real-time tracking of protein filaments in the nuclear pore complex

In human cells, the nucleus is enclosed by a structure called the nuclear pore complex (NPC). It acts as a 'gatekeeper' controlling the transport of molecules between the nucleus and the surrounding cytoplasm (the protein-containing solution in the inside of a cell).

6 Jul 2020

Colon News and Research

Early-in-life antibiotic exposure increases susceptibility to inflammatory bowel disease

Study shows promise of a major breakthrough in healing chronic diabetic ulcers

UT Southwestern Medical Center ranks among the top 50 hospitals

Finding the right treatment for people with IBD may soon become easier

An important SARS-CoV-2 enzyme is responsible for low in vivo antiviral efficacy of hydroxychloroquine

ASCRS releases updated recommendations for surgery in patients with Crohn's disease

Study may lead to more effective treatments for chronic intestinal inflammation

Study shows interferons do not induce the expression of SARS-CoV-2 cell entry receptor

Silver-plated gold nanostars could be used to identify early biomarkers of cancer

Chronic inflammation associated with IBD disrupts tissue structure of the colon, study finds

Mortality rates for complex cancer procedures vary based on hospital ratings

Upcoming phase II study to discover personalized therapy for patients at high risk for breast cancer relapse

Aspirin and flavonoids in fruits and vegetables could help prevent colorectal cancer

Corn-based diet with flavonoids alleviates IBD-like symptoms in mice

Study explores the role of gut Piezo1 in sensing of bacterial RNA

Surgical delay linked to increased risk in gastrointestinal malignancies, study finds

Real-time tracking of protein filaments in the nuclear pore complex

Study: Hypertension medications can also reduce risk of colorectal cancer

What seniors should know before going ahead with elective procedures

Novel microbiome-based diagnostic tool can identify liver fibrosis, cirrhosis

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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