Cell News and Research

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New imaging agent lights the way for surgeons during lung cancer surgery

Surgery, especially surgery to remove cancerous tumors, relies on a range of tools and techniques as well as on the skill of the surgeon.

19 Dec 2022

Cryo-electron microscopy reveals atomic structure of Staphylococcus epidermidis bacteriophage

Cryo-electron microscopy by University of Alabama at Birmingham researchers has exposed the structure of a bacterial virus with unprecedented detail.

18 Dec 2022

An assessment of T cell and antibody immunity against SARS-CoV-2 VOCs and the effect of booster shots

A new study in the journal Vaccines aimed to analyze the long-term kinetics of SARS-CoV-2 specific T cell and humoral responses following primary and booster vaccinations in previously infected individuals.

18 Dec 2022

Recent surge in group A streptococcal infections among children in UK

In an editorial published in the journal New Microbes and New Infections, scientists have highlighted the possible reasons behind a sudden rise in cases of group A streptococcal infections among children in the United Kingdom and other European countries.

18 Dec 2022

Origins of the serious cancer-like disease LCH discovered

The origins of the serious cancer-like disease LCH have been identified by researchers from Karolinska Institutet in collaboration with Karolinska University Hospital. The findings presented in Science Immunology may lead to new, targeted treatments.

16 Dec 2022

Study uncovers genetic cause of a novel developmental epilepsy syndrome

Neurodevelopmental disorders (NDD) encompass highly prevalent conditions such as autism and epilepsy, with cognitive disabilities alone affecting 1-3% of the global population.

16 Dec 2022

Research may pave the way for new antibiotics to treat high bacterial density infections

Antibiotic resistant bacteria pose of the greatest threats to global public health. In 2019, deaths due to antibiotic resistant bacteria outpaced deaths due to HIV and malaria.

16 Dec 2022

CU study proves effectiveness of new multidrug treatment for patients with stage IV melanoma

A new multidrug treatment for patients with stage IV melanoma has proven effective after a three-year clinical trial at the University of Colorado Cancer Center.

16 Dec 2022

Study provides deeper insights into skeletal muscle aging

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 23, entitled, "Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence."

16 Dec 2022

ACMG's new guideline strongly recommends the use of noninvasive prenatal screening for fetal chromosome abnormalities

The American College of Medical Genetics and Genomics (ACMG) has released a new Evidence-Based Clinical Practice Guideline (EBG), "Noninvasive prenatal screening for fetal chromosome abnormalities in a general-risk population: An evidence-based clinical guideline of the American College of Medical Genetics and Genomics."

16 Dec 2022

Researchers identify a small number of 'cheating' cancer cells under hypoxia

Researchers at UConn Health, Yale, and Johns Hopkins have identified that some cancer cells can "cheat" through escaping constraints imposed by lack of oxygen, allowing the cancer cells to continue to grow.

16 Dec 2022

Developing stem cell sheet for enhancement of angiogenesis which promotes cardiac repair

Myocardial infarction is an ischemic disease in which a coronary artery supplying blood to the heart muscle is stenotic or obstructed, resulting in cardiac tissue necrosis.

16 Dec 2022

New insights into how cells achieve cholesterol homeostasis within the cell membrane

Cholesterol is an essential component of the membrane surrounding every human cell, despite its poor reputation as a health concern when its blood levels are too high.

16 Dec 2022

Major funding to support studies of the PRPH2 gene linked to macular dystrophy

In healthy vision, a gene called PRPH2 provides instructions to make a protein called peripherin 2 (PRPH2), which plays a key role in the normal functioning of photoreceptors that detect light and color and which line the back of the eye.

16 Dec 2022

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Researchers investigated the cellular tropism, replication competence, persistence and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans, and associated histopathological changes in infected tissues.

16 Dec 2022

Novel immunotherapy offers a promising new strategy to fight hard-to-treat cancers

Scientists at UC San Francisco have engineered T cells to produce a potent anti-cancer cytokine, but only when they encounter tumor cells.

16 Dec 2022

Study shows how a specific gut microbe-generated byproduct is linked to heart failure risk

New research at Cleveland Clinic expands the link between what we eat and how the gut microbiome impacts our susceptibility to develop different diseases – in this case, how a specific gut microbe-generated byproduct is linked to heart failure risk.

16 Dec 2022

Common type 2 diabetes drug requires the presence of GDF15 cytokine to present antidiabetic effects

Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15) —a protein whose expression increases in response to cellular stress— to present its antidiabetic effects.

16 Dec 2022

NEJM study shows hidden genetic anomaly behind common late-onset cerebellar ataxia

Researchers at the University of Miami Miller School of Medicine, McGill University and other institutions have found that a well-concealed genetic variation in the gene FGF14, called a DNA tandem repeat expansion, causes a common form of late-onset cerebellar ataxia, a brain disorder that interferes with coordinated movement.

16 Dec 2022

Study provides new insights into the pathology of LATE

Limbic predominate age-related TDP-43 encephalopathy or LATE is a recently recognized form of dementia that affects memory, thinking and social skills. It mimics Alzheimer's disease or AD (and sometimes co-exists with it), but LATE is a different condition, with its own risks and causes.

16 Dec 2022

Cell News and Research

New imaging agent lights the way for surgeons during lung cancer surgery

Cryo-electron microscopy reveals atomic structure of Staphylococcus epidermidis bacteriophage

An assessment of T cell and antibody immunity against SARS-CoV-2 VOCs and the effect of booster shots

Recent surge in group A streptococcal infections among children in UK

Origins of the serious cancer-like disease LCH discovered

Study uncovers genetic cause of a novel developmental epilepsy syndrome

Research may pave the way for new antibiotics to treat high bacterial density infections

CU study proves effectiveness of new multidrug treatment for patients with stage IV melanoma

Study provides deeper insights into skeletal muscle aging

ACMG's new guideline strongly recommends the use of noninvasive prenatal screening for fetal chromosome abnormalities

Researchers identify a small number of 'cheating' cancer cells under hypoxia

Developing stem cell sheet for enhancement of angiogenesis which promotes cardiac repair

New insights into how cells achieve cholesterol homeostasis within the cell membrane

Major funding to support studies of the PRPH2 gene linked to macular dystrophy

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Novel immunotherapy offers a promising new strategy to fight hard-to-treat cancers

Study shows how a specific gut microbe-generated byproduct is linked to heart failure risk

Common type 2 diabetes drug requires the presence of GDF15 cytokine to present antidiabetic effects

NEJM study shows hidden genetic anomaly behind common late-onset cerebellar ataxia

Study provides new insights into the pathology of LATE

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