Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

Researchers identify common genetic signature among three rare skin diseases

A group of researchers lead by a lecturer from the Universidad Carlos III de Madrid, Marcela del Río, from the CIEMAT, the Rare Diseases Networking Biomedical Research Centre and Fundación Jiménez Díaz has identified a common genetic signature among three rare skin diseases or genodermatoses: recessive dystrophic epidermolysis bullosa, Kindler syndrome and xeroderma pigmentosum.

5 Mar 2019

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Differential H3K27AC marks were identified at enhancer regions of genes including c-MYC, MED1, OCT-4, NANOG, and SOX2 that can act as super-enhancers (SE), cluster of genes in non-cancerous, cancerous and metastatic PDAC cell lines.

1 Mar 2019

Overweight, obesity in adolescence associated with increased risk of renal cancer later in life

Being overweight has been linked with a higher risk of developing a form of kidney cancer called renal cell carcinoma among adults, but it's unclear if this risk is present during adolescence.

21 Feb 2019

Drug combinations could become first-line treatment for metastatic kidney cancer

A combination of two drugs - one of them an immunotherapy agent - could become a new standard, first-line treatment for patients with metastatic kidney cancer, says an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial.

18 Feb 2019

New diagnostic technique reveals key protein biomarker for bladder cancer

Label-free digital pathology using infrared imaging with subsequent proteomic analysis for bladder cancer has revealed the first protein biomarker for BC. AHNAK2 differentiates between chronic cystitis (inflammation of the bladder) and a non-muscle invasive-type BC (carcinoma in situ) which is challenging to diagnose.

12 Feb 2019

Researchers discover new therapeutic target for rare, aggressive pediatric cancers

Researchers at The University of Texas MD Anderson Cancer Center have discovered that malignant rhabdoid tumors, a rare pediatric cancer without effective treatments, may be sensitive to drugs that block the cancer cell's ability to dispose of misfolded proteins.

12 Feb 2019

Immunotherapy may be better than chemotherapy for Merkel cell carcinoma

The first study of the immunotherapy drug pembrolizumab as the initial treatment for patients with a rare but aggressive form of skin cancer known as Merkel cell carcinoma reports better responses and longer survival than expected with conventional chemotherapy.

11 Feb 2019

Immunotherapy drug found to be effective in patients with advanced Merkel cell carcinoma

A multi-center phase II clinical trial investigating pembrolizumab as a first-line and programmed cell death-1 therapy in patients with advanced Merkel cell carcinoma reports lasting tumor control, generally manageable side effects and improved overall survival.

8 Feb 2019

Osaka University-centered study finds concerning trends in cervical cancer and treatment response

Cervical cancer rates can be greatly reduced through preventive measures against the human papillomavirus along with proactive cancer screening. Japan may be showing how ignoring that knowledge could prove hazardous, as it is the only advanced economy in which the cervical cancer rate is increasing. New research adds further nuance to this situation.

7 Feb 2019

Drug treating breast cancer may be effective in treating lung and ovarian cancer

Two new papers, published simultaneously in Nature Communications and led by researchers at McGill University, offer promise that a drug currently used to treat estrogen positive breast cancer may be effective in treating two different types of cancer, one rare and one common form.

5 Feb 2019

Researchers use integrated data analysis to classify liver cancer

Liver cancer remains a major problem in healthcare globally, being the second most common cause of cancer-related death globally.

3 Feb 2019

Study sheds light on the genetic causes of tumors in salivary glands

Acinic cell carcinoma is the third most common malignant form of salivary gland cancer. These tumors are similar to normal salivary gland tissue and occur most frequently in the parotid gland.

31 Jan 2019

Injection of genetically modified virus effectively treats metastatic melanoma patients

Injection of a genetically modified virus that induces the body's own immune cells to attack metastatic melanoma effectively treated almost 40 percent of patients with tumors that could not be surgically removed, according to researchers from three prominent cancer centers in a study published as an "article in press" on the Journal of the American College of Surgeons website in advance of print publication.

28 Jan 2019

Regular use of aspirin may help some patients survive head and neck cancer

Regular use of aspirin or other nonsteroidal anti-inflammatory drugs may help some patients with head and neck cancer survive the disease, according to a study led by Professor Jennifer Grandis at the University of California, San Francisco.

27 Jan 2019

Regular use of common pain relief medicines improves survival for head and neck cancer patients

Regular use of a common type of medication, such as aspirin and ibuprofen, significantly improves survival for a third or more patients with head and neck cancer, a new study led by UC San Francisco has found.

25 Jan 2019

Nine early career scientists named 2019 recipients of the Damon Runyon-Rachleff Innovation Award

The Damon Runyon Cancer Research Foundation announced that nine scientists with novel approaches to fighting cancer have been named 2019 recipients of the Damon Runyon-Rachleff Innovation Award.

24 Jan 2019

Molecular profiling of precancerous lung lesions could lead to early detection and new treatments

The world's first genetic sequencing of precancerous lung lesions could pave the way for very early detection and new treatments, reports a new study led by UCL researchers.

21 Jan 2019

Branched-chain amino acids in tumors can be targeted to prevent and treat cancer

Researchers at A*STAR's Singapore Bioimaging Consortium have discovered that branched-chain amino acids in tumors can be targeted to prevent and treat cancer. Together with collaborators from the United States and National Cancer Centre Singapore, they found that some cancers potently suppress the catabolism (breakdown) of BCAAs.

21 Jan 2019

Scientists propose quick and pain-free method for diagnosing kidney cancer

Sechenov University together with their German colleagues suggest a new highly sensitive, quick, and pain-free method for diagnosing kidney cancer.

21 Jan 2019

UNIST researcher named as recipient of Merck’s 2018 Life Science Awards

Jun Ho Lee, a doctroral student in Life Sciences at UNIST, has been named as a recipient of Merck's 2018 Life Science Awards in Tumor Biology, receiving the grand prize of $10,000.

21 Jan 2019

Carcinoma News and Research

Further Reading

Researchers identify common genetic signature among three rare skin diseases

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Overweight, obesity in adolescence associated with increased risk of renal cancer later in life

Drug combinations could become first-line treatment for metastatic kidney cancer

New diagnostic technique reveals key protein biomarker for bladder cancer

Researchers discover new therapeutic target for rare, aggressive pediatric cancers

Immunotherapy may be better than chemotherapy for Merkel cell carcinoma

Immunotherapy drug found to be effective in patients with advanced Merkel cell carcinoma

Osaka University-centered study finds concerning trends in cervical cancer and treatment response

Drug treating breast cancer may be effective in treating lung and ovarian cancer

Researchers use integrated data analysis to classify liver cancer

Study sheds light on the genetic causes of tumors in salivary glands

Injection of genetically modified virus effectively treats metastatic melanoma patients

Regular use of aspirin may help some patients survive head and neck cancer

Regular use of common pain relief medicines improves survival for head and neck cancer patients

Nine early career scientists named 2019 recipients of the Damon Runyon-Rachleff Innovation Award

Molecular profiling of precancerous lung lesions could lead to early detection and new treatments

Branched-chain amino acids in tumors can be targeted to prevent and treat cancer

Scientists propose quick and pain-free method for diagnosing kidney cancer

UNIST researcher named as recipient of Merck’s 2018 Life Science Awards

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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