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Highly prevalent gene variants in African Americans contribute to kidney disease

African Americans have a heightened risk of developing chronic and end-stage kidney disease. This association has been attributed to two common genetic variants - named G1 and G2 -- in APOL1, a gene that codes for a human-specific protein.

1 Mar 2017

Researchers develop testing program to study potency of vaccines for neglected tropical diseases

A new generation of vaccines for neglected tropical diseases is moving into clinical trials, and understanding the long-term stability and effectiveness of these vaccines over periods of storage is key to their success.

1 Mar 2017

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Researchers at Monash University and Peter MacCallum Cancer Centre have identified for the first time how a new class of epigenetic drug engages with the immune system to kill off cancer cells, offering powerful new pathways for enhanced blood cancer therapies.

1 Mar 2017

Harvard researchers develop new portable device that can quickly produce highly aligned nanofibers

Harvard researchers have developed a lightweight, portable nanofiber fabrication device that could one day be used to dress wounds on a battlefield or dress shoppers in customizable fabrics.

1 Mar 2017

Study offers hope of improved treatment for people with severe asthma

Improved treatments for people with severe asthma are a 'step closer' after a research team led by the University of Leicester identified a breakthrough in the cause of airway narrowing.

1 Mar 2017

Duke researchers discover potential cause for ALS syndromes using mouse models

A team of researchers at Duke University Medical Center led by Dr. Paulo Ferreira and whose work was supported by the National Institutes of Health has found that derailing the transport of certain receptors that carry cargoes from and to the nucleus of motor neurons causes motor neuron disease in mice.

1 Mar 2017

Using Spherical Nucleic Acids to Track and Treat Disease

Spherical nucleic acids are structures that are made by taking a nanoparticle template and using chemistry to arrange short strands of DNA or RNA on the surface of those particles. The spherical core of the nanoparticle creates a spherical arrangement of DNA or RNA, similar to tiny little balls of nucleic acids.

From Pittcon 1 Mar 2017

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

University of North Carolina Lineberger Comprehensive Cancer Center researchers have achieved a major milestone with the launch of two clinical trials testing an experimental therapy in which patients' own immune cells are genetically engineered to fight their cancer.

1 Mar 2017

UC scientists discover new strategy to personalize blood, brain cancer therapy

Researchers at the University of Cincinnati College of Medicine have discovered a new potential strategy to personalize therapy for brain and blood cancers.

1 Mar 2017

Emory researchers uncover novel link between SV2C protein and Parkinson's disease

Emory investigators have discovered a novel link between a protein called SV2C and Parkinson's disease (PD). Prior work had suggested that the SV2C gene was associated with the curious ability of cigarette smoking to reduce PD risk.

28 Feb 2017

Novel NMR spectroscopy platform holds potential to revolutionize drug development practices

Implementation of a new nuclear magnetic resonance spectroscopy platform will provide professors Nicolas Doucet and Steven LaPlante of Centre INRS-Institut Armand-Frappier with a powerful new tool for conducting an ambitious research program aimed at identifying new therapeutic molecules.

28 Feb 2017

Danish researchers get closer to finding treatment for malignant cerebral tumour in children

DIPG (Diffuse Intrinsic Pontine Glioma) is a rare malignant cerebral tumour in children. It has only a 1% 5-year survival rate, amongst other things because it is not possible to operate because the tumour is located in the brain stem.

28 Feb 2017

TUM experts decipher secrets of Achilles' heel

Walking, running, sprinting -- every movement of the foot stretches the Achilles' tendon. When jumping, the loads can approach ten times the body weight.

28 Feb 2017

OU study identifies numeracy as decision delay risk factor for individuals experiencing ACS

In a recent study to determine why some individuals who experience symptoms for acute coronary syndrome decide to seek medical attention more quickly than others, a University of Oklahoma researcher has identified numeracy -- the ability to understand and apply numerical concepts as the primary decision delay risk factor for individuals experiencing the medical condition.

28 Feb 2017

Biologists develop new way to inhibit cancer cell cleanup mechanism

The genomes of cancer cells--cells that do not obey signals to stop reproducing--are riddled with genetic mutations, causing them inadvertently to make many dysfunctional proteins.

28 Feb 2017

Study suggests new strategy for treating Alzheimer's disease

Alzheimer's disease (AD) is one of the most common form of dementia. In search for new drugs for AD, the research team, led by Professor Mi Hee Lim of Natural Science at UNIST has developed a metal-based substance that works like a pair of genetic scissors to cut out amyloid-β (Aβ), the hallmark protein of AD.

28 Feb 2017

Scientists develop in vitro stem cell-based bioassay for detecting biological activity of BoNTs

Scientists at the Institute for Infectious Diseases, University of Bern have developed an in vitro stem cell-based bioassay grown on multi-electrode arrays capable of detecting the biological activity of Clostridium botulinum neurotoxins.

28 Feb 2017

Researchers justify alternative theory about cause of type 1 diabetes

An international team of researchers led by City of Hope's Bart Roep, Ph.D., the Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes and professor/founding chair of the Department of Diabetes Immunology, has been able to justify an alternative theory about the cause of type 1 diabetes (T1D) through experimental work.

28 Feb 2017

Scientists discover how genetic mutation disarms tumor-suppressing BRCA1 proteins in breast cancer

Of the more than 3 million people with breast cancer in the United Stated, about 10 percent carry an inherited mutation in their BRCA1 gene. In health, the gene is responsible for suppressing tumors. In disease, the gene goes terribly awry.

28 Feb 2017

MIT biological engineers develop method to measure heme levels inside malaria parasite

The iron-containing molecule heme is necessary for life. Cells require heme to perform the chemical reactions that produce energy, among other critical tasks.

28 Feb 2017

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G Protein News and Research

Highly prevalent gene variants in African Americans contribute to kidney disease

Researchers develop testing program to study potency of vaccines for neglected tropical diseases

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Harvard researchers develop new portable device that can quickly produce highly aligned nanofibers

Study offers hope of improved treatment for people with severe asthma

Duke researchers discover potential cause for ALS syndromes using mouse models

Using Spherical Nucleic Acids to Track and Treat Disease

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

UC scientists discover new strategy to personalize blood, brain cancer therapy

Emory researchers uncover novel link between SV2C protein and Parkinson's disease

Novel NMR spectroscopy platform holds potential to revolutionize drug development practices

Danish researchers get closer to finding treatment for malignant cerebral tumour in children

TUM experts decipher secrets of Achilles' heel

OU study identifies numeracy as decision delay risk factor for individuals experiencing ACS

Biologists develop new way to inhibit cancer cell cleanup mechanism

Study suggests new strategy for treating Alzheimer's disease

Scientists develop in vitro stem cell-based bioassay for detecting biological activity of BoNTs

Researchers justify alternative theory about cause of type 1 diabetes

Scientists discover how genetic mutation disarms tumor-suppressing BRCA1 proteins in breast cancer

MIT biological engineers develop method to measure heme levels inside malaria parasite

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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