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Study unravels how lysosomal damage response pathways prevent kidney injury

Human cells need to work like well-oiled machines to keep our bodies running as they should. Waste products such as misfolded proteins, damaged cellular components, and carbohydrates get in the way and must be quickly disposed of.

28 Sep 2020

UCLA researchers receive $13 million NIH grant to combat melanoma

UCLA researchers have received a $13 million grant from the National Institutes of Health to find new ways to overcome melanoma resistance to some of the most promising targeted therapies and immunotherapies.

28 Sep 2020

Study pinpoints heating element in vaping devices as cause for lung injuries

Early results of an experimental vaping study have shown significant lung injury from E-cigarette (eC) devices with nickel-chromium alloy heating elements.

28 Sep 2020

Stanford researchers unravel how a common genetic deletion elevates schizophrenia risk

A common genetic deletion boosts the risk for schizophrenia by 30-fold. Generating nerve cells from people with the deletion has showed Stanford researchers why.

28 Sep 2020

COVID-19 may deteriorate men's testosterone levels, new data suggests

For the first time, data from a study with patients hospitalized due to COVID-19 suggest that the disease might deteriorate men's testosterone levels.

28 Sep 2020

Science academies present joint statement on health, sustainability, and digitization

In the run-up to the summit of the G20 countries in November 2020 to be held in Riyadh (Saudi Arabia), the science academies of these countries have presented their joint statement "Foresight: Science for Navigating Critical Transitions".

28 Sep 2020

Brain wiring genes may be linked to a significant portion of cerebral palsy cases

In an article published in Nature Genetics, researchers confirm that about 14% of all cases of cerebral palsy, a disabling brain disorder for which there are no cures, may be linked to a patient's genes and suggest that many of those genes control how brain circuits become wired during early development.

28 Sep 2020

Epigenetic changes in the brain drive late-onset Alzheimer's disease

New findings suggest that late-onset Alzheimer's Disease is driven by epigenetic changes -- how and when certain genes are turned on and off -- in the brain. Results were published today in Nature Genetics.

28 Sep 2020

Study reveals underrepresentation of older people in COVID-19 trials

A study published today in the Journal of the American Medical Association Internal Medicine revealed that older persons are highly likely to be excluded from the majority of COVID-19 trials that seek to establish effective treatments, as well as find a preventive vaccine.

28 Sep 2020

NCCN publishes new clinical practice guidelines for pediatric Hodgkin lymphoma

The National Comprehensive Cancer Network today announced the publication of new NCCN Clinical Practice Guidelines in Oncology for Pediatric Hodgkin Lymphoma. Hodgkin lymphoma is one of the most curable forms of pediatric cancer, with long-term survival rates of 90% or higher.

28 Sep 2020

WHO develops new guidelines to prevent mental health conditions among adolescents

New guidelines from WHO recommend a set of psychosocial interventions to promote mental health and prevent mental health conditions among adolescents, aged 10-19 years.

28 Sep 2020

Study may explain why hormone therapy slows progression of heart disease

As one of the most common treatments for effectively managing menopause symptoms, hormone therapy (HT) is also known to provide multiple health benefits, including slowing the progression of atherosclerosis.

28 Sep 2020

College re-openings could cause 3,200 extra cases of COVID-19 per day in the US

A new report published in the preprint server medRxiv in September 2020 shows the close relationship between the re-opening of colleges, especially those drawing students from high-incidence areas, and those offering in-person instruction, and the significant increase in the incidence of COVID-19 among students and the community.

27 Sep 2020

New study highlights success of health program's clinical van and street outreach

A novel mobile health program created in early 2018 by the Kraft Center for Community Health at Massachusetts General Hospital (MGH) has proven to be an effective model for bringing opioid addiction treatment services directly to marginalized individuals, particularly the homeless, a population that faces the highest risk of near-term death from drug overdose.

26 Sep 2020

Translational research training program helps students to better understand patients' problems

Translational research aims to speed research breakthroughs into the clinic. And yet, training for basic scientists and clinicians too often remains siloed, leading to divergent cultures and a loss of opportunity for cross-disciplinary collaboration.

26 Sep 2020

New study links 160 genes to brain shrinkage

A new study implicates 160 genes in brain shrinkage seen on MRIs of 45,000 healthy adults. The shrinkage is in the cortex, the dimply outer layer of the brain that gives rise to thinking, awareness and action, and largely consists of gray matter.

25 Sep 2020

Students without pre-existing mental health issues more severely affected by COVID-19 stressors

Surprisingly, university students without pre-existing mental health concerns seem to be suffering greater psychological distress during the pandemic than their peers with pre-existing mental health problems according to a study of close to 800 university students in Toronto carried out by researchers from McGill and University of Toronto.

25 Sep 2020

New diagnostic tool may allow on-the-spot detection of coronavirus infection

Scientists at the University of Warwick have demonstrated that a potential diagnostic tool for detecting Covid-19 using sugars will work with a virus rather than just its proteins, a significant step in making it a viable test in future.

25 Sep 2020

Researchers advance novel compounds to help treat C. difficile infection

Clostridioides difficile, or C. diff, is the leading cause of health care-associated infection in the U.S.

25 Sep 2020

Study elucidates the developmental trajectory of self-esteem in Japan

Self-esteem does not remain constant through life, but changes as a person develops. A large number of studies conducted on this topic, mainly in the United States, have shown that self-esteem is high in childhood, declines in adolescence, but then continues to increase throughout adulthood, peaking in the 50s and 60s, and declining thereafter.

25 Sep 2020