Genes News and Research

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Gene editing technique helps uncover potential new drug targets for KRAS-driven cancers

Cancers driven by mutations in the KRAS gene are among the most deadly. For decades, researchers have tried unsuccessfully to directly target mutant KRAS proteins as a means to treat tumors.

28 Sep 2017

IMB researchers unveil mystery of aging process

Researchers at the Institute of Molecular Biology in Mainz have made a breakthrough in understanding the origin of the aging process. They have identified that genes belonging to a process called autophagy, which is one of the cells most critical survival processes, promote health and fitness in young worms but drive the process of aging later in life.

27 Sep 2017

Genetic testing can improve safety of common blood thinner, study shows

Warfarin is a blood thinner that is commonly prescribed to patients to prevent life-threatening blood clots. Despite its longtime use, warfarin remains tricky to dose because a person's genetic makeup influences how the drug is processed in the body.

27 Sep 2017

Trial identifies genetic fault that affects treatment response in leukemia patients

A genetic fault has been identified in people with an aggressive type of leukemia that can significantly affect how they respond to treatment.

27 Sep 2017

Sophisticated 'social control' system allows embryos to protect purity of pluripotent cell population

A sophisticated system of 'social control' operating between neighboring cells allows embryos to protect the purity of their pluripotent cell population, which is able to generate all body tissues.

27 Sep 2017

Research reveals curious pattern of autism recurrence based on gender

Having one child with autism is a well-known risk factor for having another one with the same disorder, but whether and how a sibling's gender influences this risk has remained largely unknown.

26 Sep 2017

MIT study sheds light on flu viruses' rapid evolution

Influenza viruses mutate rapidly, which is why flu vaccines have to be redesigned every year. A new study from MIT sheds light on just how these viruses evolve so quickly and offers a potential way to slow them down.

26 Sep 2017

MIPT scientist proposes unique model to predict cancer development

A scientist from the Moscow Institute of Physics and Technology has proposed a model that can predict the number of key carcinogenic events for each cancer type based on the relationship between morbidity and age.

26 Sep 2017

New approaches to treat aggressive NUT midline carcinoma

Precision medicine, which custom-tailors therapies to the needs of individual patients, is becoming more and more important in cancer therapy. Today, molecular-biological diagnostics can precisely identify alterations in tumor cells.

26 Sep 2017

Study: Gene linked to schizophrenia risk controls early neurodevelopment

A gene associated with the risk of schizophrenia regulates critical components of early brain development, according to a new study led by researchers from Penn State University.

26 Sep 2017

Rutgers scientists use genetic engineering technique to create brain cells for studying Tourette’s

Scientists at Rutgers University-New Brunswick used a genetic engineering technique for the first time to create brain cells from the blood cells of individuals in a three-generation family with Tourette syndrome to help determine what causes the disease.

25 Sep 2017

UAB researchers detail underlying mechanism leading to age-associated osteoporosis

A major health problem in older people is age-associated osteoporosis -- the thinning of bone and the loss of bone density that increases the risk of fractures. Often this is accompanied by an increase in fat cells in the bone marrow.

22 Sep 2017

Study identifies two genes involved in invasive group A Streptococcus infections

Group A Streptococcus bacteria cause a variety of illnesses that range from mild nuisances like strep throat to life-threatening conditions including pneumonia, toxic shock syndrome and the flesh-eating disease formally known as necrotizing fasciitis.

22 Sep 2017

Genome-wide study reveals how transposons get prepared for jumping

The genome of a typical organism consists of many genes that are stringed like beads. This alignment has been surprisingly stable even over very long evolutionary periods. In addition to these genes, there are also many mobile elements, referred to as parasitic, that are spread across the whole genome and aggregated into different families according to their relatedness.

22 Sep 2017

Targeting mutant p53 specific binding protein could lead to new therapeutic strategies for cancer patients

Research by Rutgers Cancer Institute of New Jersey investigators shows the targeting of a binding protein of mutant p53 known as Rac1 could lead to new therapeutic strategies for patients whose cancer carries mutations in the p53 gene.

22 Sep 2017

Researchers use gene therapy to restore hearing and balance in mouse model of Usher syndrome

Hearing loss, sometimes associated with other disorders such as balance defects, is the most common sensory deficit, affecting more than 280 million people worldwide, according to WHO. In France, one child in 700 is born with severe or profound hearing loss, and one in every 1,000 will lose their sense of hearing before adulthood.

22 Sep 2017

New syndrome caused by biallelic mutations predisposes the body to tumors

A new syndrome caused by biallelic mutations - those produced in both gene copies inherited from the mother and father - in the FANCM gene predisposes the body to the appearance of tumours and causes rejection to chemotherapy treatments.

22 Sep 2017

Researchers discover mechanism of drug resistance for ovarian and breast cancer cells

Researchers from the People's Friendship University of Russia have studied the mechanism of drug resistance for ovarian and breast cancer cells.

22 Sep 2017

New tissue-chip research aims to speed drug development for two genetic forms of epilepsy

An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an "organ-on-chip" model for two genetic forms of epilepsy. These disorders affect both brain and heart and improved modeling could lead to new drug treatments.

22 Sep 2017

Study may contribute to genetic understanding of high-altitude adaptation

Many research groups have recently explored human adaptation and successfully identified candidate genes to high altitude living among three major far-flung global populations: Tibetans, Ethiopians and Peruvians.

22 Sep 2017

Genes News and Research

Gene editing technique helps uncover potential new drug targets for KRAS-driven cancers

IMB researchers unveil mystery of aging process

Genetic testing can improve safety of common blood thinner, study shows

Trial identifies genetic fault that affects treatment response in leukemia patients

Sophisticated 'social control' system allows embryos to protect purity of pluripotent cell population

Research reveals curious pattern of autism recurrence based on gender

MIT study sheds light on flu viruses' rapid evolution

MIPT scientist proposes unique model to predict cancer development

New approaches to treat aggressive NUT midline carcinoma

Study: Gene linked to schizophrenia risk controls early neurodevelopment

Rutgers scientists use genetic engineering technique to create brain cells for studying Tourette’s

UAB researchers detail underlying mechanism leading to age-associated osteoporosis

Study identifies two genes involved in invasive group A Streptococcus infections

Genome-wide study reveals how transposons get prepared for jumping

Targeting mutant p53 specific binding protein could lead to new therapeutic strategies for cancer patients

Researchers use gene therapy to restore hearing and balance in mouse model of Usher syndrome

New syndrome caused by biallelic mutations predisposes the body to tumors

Researchers discover mechanism of drug resistance for ovarian and breast cancer cells

New tissue-chip research aims to speed drug development for two genetic forms of epilepsy

Study may contribute to genetic understanding of high-altitude adaptation

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