Microscopy News and Research

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Rapid and efficient strategy for the development and design of SARS-CoV-2 neutralizing humanized nanobody constructs

Researchers developed humanized nanobodies that neutralize SARS-CoV-2.

16 Aug 2022

Scientists explore nanomolar inhibition of SARS-CoV-2 infection via unmodified peptide targeting spike protein pre-hairpin intermediate

In a new study, scientists identified an unmodified peptide addressing pre-hairpin spike (S) protein intermediate inhibiting SARS-CoV-2 infection.

15 Aug 2022

Bispecific antibody exhibits high breadth and potency against SARS-CoV-2 Omicron sub-lineages

In a new study, researchers developed bispecific-antibodies (bsAbs) against SARS-CoV-2 Omicron sub-lineages.

12 Aug 2022

New method for 3D culture accurately quantifies how cancer cells generate forces to spread within tissue

Research to understand how cancers grow and spread has conventionally been done on two-dimensional, flat cultures of cells, which is very different to the three-dimensional structure of cells in the body.

12 Aug 2022

Study finds genetic alterations in healthy cells that match with the tumor cells

A new study offers the possibility of unmasking genetic mutations in an organ well before commonly-used screening techniques detect signs of cancer.

10 Aug 2022

Linkam puts cryo in the spotlight at M&M 2022

Market leader in temperature and environmental-controlled microscopy, Linkam, presented its range of cryo workflow solutions and sample characterisation tools at Microscopy and Microanalysis (M&M) 2022.

From Linkam Scientific Instruments 10 Aug 2022

A broad sarbecovirus-neutralizing antibody cocktail

Researchers present a rational approach for identifying SARS-CoV-2 receptor-binding domain-targeted broad neutralizing antibody cocktails.

9 Aug 2022

WVU professor receives $1.6 million to expand research on brain circuits

A fruit fly walks on a rolling ball. As it meanders, Kevin Daly, biology professor at West Virginia University, looks deep into its brain through a specialized microscope.

9 Aug 2022

Researchers develop a long-acting injectable formulation of the anti-TB drug rifabutin

In 2020, more than 1.5 million people around the world died of tuberculosis, marking the first time in more than a decade that annual TB deaths had increased and demonstrating the global need for better access to treatments.

8 Aug 2022

Researchers unravel the mechanism of teixobactin at the atomic level

Researchers explored the mechanisms underlying the bactericidal action of teixobactin at an atomic level.

8 Aug 2022

Researchers create a physical wiring diagram of the human immune system

In a new study, researchers systematically mapped the surface proteins on human leukocytes to examine interactions between their cell-surface proteomes and develop a physical wiring diagram encapsulating the diversity of surface protein architectures found across all major subsets of leukocytes.

8 Aug 2022

NIH researchers develop three-dimensional structure of twinkle protein

Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases.

5 Aug 2022

Researchers identify mechanistic principles for engineering antibodies to enhance cadherin adhesion

Future treatments for advanced cancer could work by sticking cancer cells in place and preventing their spread around the body. A new study by researchers at the University of California, Davis, and the University of Washington shows how an antibody strengthens bonds between cells. The work is published Aug. 3 in Proceedings of the National Academy of Sciences.

5 Aug 2022

Polymer-embedded copper-based nanoparticles prevent surface contamination by viruses

In a new study, researchers developed nanocomposite coatings to prevent surface contamination by a human coronavirus (HCoV).

4 Aug 2022

Researchers unravel mechanism of action of bacterial Tc toxin in fatal attacks

A harmful and often deadly substance made by bacteria, a bacterial toxin manipulates host cell functions and disrupts vital cell processes in a living organism.

3 Aug 2022

Study defines how cannabis cells make cannabinoids

For the first time, plant biologists have defined the high-efficiency "hacks" that cannabis cells use to make cannabinoids (THC/CBD). Although many biotechnology companies are currently trying to engineer THC/CBD outside the plant in yeast or cell cultures, it is largely unknown how the plant does it naturally.

3 Aug 2022

Novel algorithm provides rich, detailed information on protein location and function within a cell

Humans are good at looking at images and finding patterns or making comparisons. Look at a collection of dog photos, for example, and you can sort them by color, by ear size, by face shape, and so on. But could you compare them quantitatively? And perhaps more intriguingly, could a machine extract meaningful information from images that humans can't?

2 Aug 2022

Jianhua Zhao secures $2.4 million NIGMS grant to study the molecular machinery of proteolysis

Assistant Professor Jianhua Zhao, Ph.D., has been awarded a unique and competitive grant from the National Institute of General Medical Sciences, part of the National Institutes of Health.

2 Aug 2022

Plasma myosin light chain 9 levels may be better predictor of COVID-19 severity than blood biomarkers

In a new study, researchers found elevated plasma levels of myosin light chain 9 (Myl9) in COVID-19 patients with a fatal disease.

2 Aug 2022

CrestOptics’ DeepSIM super resolution confocal microscope module named by Microscopy Today as a top 10 best microscopy innovation of 2022

CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy and diagnostic applications, has been recognised as developing one of the ten best microscopy innovations in the 2022 Microscopy Today Innovation Awards, DeepSIM.

1 Aug 2022

Microscopy News and Research

Rapid and efficient strategy for the development and design of SARS-CoV-2 neutralizing humanized nanobody constructs

Scientists explore nanomolar inhibition of SARS-CoV-2 infection via unmodified peptide targeting spike protein pre-hairpin intermediate

Bispecific antibody exhibits high breadth and potency against SARS-CoV-2 Omicron sub-lineages

New method for 3D culture accurately quantifies how cancer cells generate forces to spread within tissue

Study finds genetic alterations in healthy cells that match with the tumor cells

Linkam puts cryo in the spotlight at M&M 2022

A broad sarbecovirus-neutralizing antibody cocktail

WVU professor receives $1.6 million to expand research on brain circuits

Researchers develop a long-acting injectable formulation of the anti-TB drug rifabutin

Researchers unravel the mechanism of teixobactin at the atomic level

Researchers create a physical wiring diagram of the human immune system

NIH researchers develop three-dimensional structure of twinkle protein

Researchers identify mechanistic principles for engineering antibodies to enhance cadherin adhesion

Polymer-embedded copper-based nanoparticles prevent surface contamination by viruses

Researchers unravel mechanism of action of bacterial Tc toxin in fatal attacks

Study defines how cannabis cells make cannabinoids

Novel algorithm provides rich, detailed information on protein location and function within a cell

Jianhua Zhao secures $2.4 million NIGMS grant to study the molecular machinery of proteolysis

Plasma myosin light chain 9 levels may be better predictor of COVID-19 severity than blood biomarkers

CrestOptics’ DeepSIM super resolution confocal microscope module named by Microscopy Today as a top 10 best microscopy innovation of 2022

Industry Focus eBook - Life Science Microscopy (2nd Edition) eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

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