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Individuals with early-onset diabetes, hypertension more likely to develop primary open-angle glaucoma

The earlier individuals develop Type 2 diabetes or hypertension in life, the earlier they are likely to develop primary open-angle glaucoma (POAG), the leading cause of irreversible blindness worldwide, researchers from UT Southwestern reported in a recent study.

29 Aug 2022

Anonymous $5.75 million gift will enable UVA to fight against rare blood cancers

A gift of more than $5.75 million from anonymous donors will allow UVA Cancer Center to speed the development of new treatments for rare blood cancers and provide more patients with these cancers access to cutting-edge clinical trials.

29 Aug 2022

Full-dose anticoagulation lowers the risk of blood clotting complications in COVID-19 patients

A clinical trial of patients with COVID-19 led by investigators at the TIMI Study Group at Brigham and Women's Hospital and the Critical Care Cardiology Trials Network has found that full-dose anticoagulation lowers the risk of blood clotting complications compared with standard-dose prophylactic anticoagulation.

29 Aug 2022

Study shows how the brain's tool for waste clearance malfunctions during bacterial meningitis

Bacterial meningitis is a life-threatening infectious disease of the brain that leaves many survivors with long-lasting neurological impairments.

29 Aug 2022

Oncolytic viruses boost the immune capacity to effectively target and destroy cancer cells

The immune system has evolved to safeguard the body from a wildly diverse range of potential threats. Among these are bacterial diseases, including plague, cholera, diphtheria and Lyme disease, and viral contagions such as influenza, Ebola virus and SARS CoV-2.

29 Aug 2022

Performing moderate or vigorous physical activity may lower the risk of heart failure

A six-year analysis of more than 94,000 adults in the U.K. Biobank with no history of heart failure at enrollment has found that engaging in moderate or vigorous physical activity may lower the risk of developing heart failure, according to new research published today in the American Heart Association's flagship journal Circulation.

29 Aug 2022

Combination of anemia and weak muscles increases the risk of death in older people

A study by researchers at the Federal University of São Carlos in Brazil and University College London in the United Kingdom shows that a combination of anemia and weak muscles in older people heightens the risk of death in ten years by 64% for men and by 117% for women.

29 Aug 2022

Herpesvirus-6 and Epstein–Barr virus reactivation across acute SARS-CoV-2 patients

In a new story, scientists explored human herpesvirus-6 (HHV-6) and Epstein–Barr virus (EBV) reactivation among acute coronavirus disease 2019 (COVID-19) patients.

29 Aug 2022

Study identifies two potential serological biomarkers of monkeypox infection

In a new study, researchers pursued two monkeypox virus (MPXV) immune targets, A35R and H3L, that could be deployed in a serological assay to identify recent MPXV cases.

29 Aug 2022

Potential cause of racial disparity affecting infants with congenital heart disease discovered

Race was already known to matter when it came to health outcomes for infants with congenital heart disease (CHD), the most common birth defect, affecting 1 in 100 live births.

29 Aug 2022

People with autoimmune disorder have a higher risk of developing cardiovascular disease

Around ten percent of the population in high income regions like Europe and the United States has been diagnosed with one or multiple autoimmune disorders.

29 Aug 2022

The incidence rate, distribution, characteristics, and outcomes of neonatal COVID-19

Researchers assessed the epidemiology of neonatal COVID-19 infections.

29 Aug 2022

What are the clinical characteristics and complications of patients with a monkeypox infection?

Researchers described the clinical characteristics and complications of monkeypox virus infections.

29 Aug 2022

How does the maternal immune response balance SARS-CoV-2 antiviral responses with transplacental transfer of protection to the fetus?

Researchers found that in SARS-CoV-2 maternal infection, the balance between antiviral response and transplacental transfer of humoral and cellular protection relies on maternal IL-6 and IL10.

29 Aug 2022

$SGLT2 inhibitors reduce cardiovascular events among heart failure patients with mildly reduced and preserved ejection fraction$

SGLT2 inhibitors reduce cardiovascular events among heart failure patients with mildly reduced and preserved ejection fraction

An analysis of more than 12,000 patients has found that the SGLT2 inhibitors dapagliflozin and empagliflozin reduce cardiovascular death or hospitalization for heart failure by 20% in heart failure patients with mildly reduced and preserved ejection fraction.

28 Aug 2022

Percutaneous coronary intervention provides no benefit in patients with severe left ventricular dysfunction

Percutaneous coronary intervention (PCI) does not reduce all-cause mortality or heart failure hospitalization in patients with severe left ventricular dysfunction and extensive coronary artery disease, according to late breaking research presented in a Hot Line session today at ESC Congress 2022.

28 Aug 2022

Target blood pressure of 77 mmHg provides no benefit for comatose cardiac arrest survivors

A target blood pressure of 77 mmHg provides no benefit to survival or neurological outcome in comatose cardiac arrest survivors compared with a 63 mmHg target, according to late breaking research presented in a Hot Line session today at ESC Congress 2022.

28 Aug 2022

Restrictive oxygenation target in comatose, post cardiac arrest patients does not cause harm

A restrictive oxygenation target in comatose patients resuscitated after out-of-hospital cardiac arrest does not worsen survival or neurological outcome compared with a liberal target, according to late breaking research presented in a Hot Line session today at ESC Congress 2022.

28 Aug 2022

Cardiovascular screening may lower the risk of death, heart attack and stroke in 65 to 69 year-olds

A randomized trial in more than 45,000 men has suggested that cardiovascular screening including cardiac imaging, blood pressure measurement and blood tests, plus treatment if needed, may lower the risk of death, heart attack and stroke in 65 to 69 year-olds.

28 Aug 2022

Penn State receives $1.6 million grant to study the link between COVID-19 and cognitive decline

As populations around the globe age, dementia - often caused by Alzheimer's disease and related disorders - is a growing health issue for older adults worldwide.

26 Aug 2022

Blood News and Research

Individuals with early-onset diabetes, hypertension more likely to develop primary open-angle glaucoma

Anonymous $5.75 million gift will enable UVA to fight against rare blood cancers

Full-dose anticoagulation lowers the risk of blood clotting complications in COVID-19 patients

Study shows how the brain's tool for waste clearance malfunctions during bacterial meningitis

Oncolytic viruses boost the immune capacity to effectively target and destroy cancer cells

Performing moderate or vigorous physical activity may lower the risk of heart failure

Combination of anemia and weak muscles increases the risk of death in older people

Herpesvirus-6 and Epstein–Barr virus reactivation across acute SARS-CoV-2 patients

Study identifies two potential serological biomarkers of monkeypox infection

Potential cause of racial disparity affecting infants with congenital heart disease discovered

People with autoimmune disorder have a higher risk of developing cardiovascular disease

The incidence rate, distribution, characteristics, and outcomes of neonatal COVID-19

What are the clinical characteristics and complications of patients with a monkeypox infection?

How does the maternal immune response balance SARS-CoV-2 antiviral responses with transplacental transfer of protection to the fetus?

SGLT2 inhibitors reduce cardiovascular events among heart failure patients with mildly reduced and preserved ejection fraction

Percutaneous coronary intervention provides no benefit in patients with severe left ventricular dysfunction

Target blood pressure of 77 mmHg provides no benefit for comatose cardiac arrest survivors

Restrictive oxygenation target in comatose, post cardiac arrest patients does not cause harm

Cardiovascular screening may lower the risk of death, heart attack and stroke in 65 to 69 year-olds

Penn State receives $1.6 million grant to study the link between COVID-19 and cognitive decline

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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