Genes News and Research

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Study provides promising framework to anticipate drug resistance in cancer

Being able to predict the resistance or sensitivity of a tumor cell to a drug is a key success-factor of cancer precision therapy.

14 Aug 2017

Counteracting premature aging

Aging is the continuing process of such stress exposures, and with advancing age (normal aging), we must carry lots of senescent cells within our bodies. Senescent cells also often provide some ‘bad influences’ to surrounding healthy cells; such as chronic inflammation and tumorigenesis

14 Aug 2017

Goldfish survive lack of oxygen for months by converting their carbs to alcohol

A new study has shown that goldfish and similar crucian carps can live up to five months in icy lakes with extremely low or no oxygen. Evolution of the fish has enabled them to develop a set of enzymes that can help the fish convert their carbohydrates into alcohol.

13 Aug 2017

USC scientists obtain molecular 'how to' guide for growing hair

How does the skin develop follicles and eventually sprout hair? A USC-led study, published in the Proceedings of the National Academy of Sciences (PNAS), addresses this question using insights gleaned from organoids, 3D assemblies of cells possessing rudimentary skin structure and function--including the ability to grow hair.

11 Aug 2017

Duke researchers map evolution of sex chromosomes in fungus linked to human disease

Biologically speaking, nearly every species on Earth has two opposite sexes, male and female. But with some fungi and other microbes, sex can be a lot more complicated.

11 Aug 2017

Better analysis of kidney tumor samples

Every year, just over 1000 people are diagnosed with kidney cancer in Sweden. The three most common variants are clear cell, papillary and chromophobe renal cancer.

11 Aug 2017

Experts highlight need to respect women's autonomy in prenatal testing

Noninvasive fetal genetic sequencing done early in pregnancy is poised to become a routine part of prenatal care.

11 Aug 2017

Feinstein researcher awarded NIH grant to better understand genetic causes of Alzheimer's disease

Feinstein Institute for Medical Research Assistant Professor Yun Freudenberg-Hua, MD, has been awarded a five-year, $600,000 grant from the National Institutes of Health's National Institute on Aging to identify genetic risk factors for Alzheimer's disease.

11 Aug 2017

Researchers develop new technique to locate pathogenic mutations in dark, non-coding genome

When doctors can't find a diagnosis for patient's disease, they turn to genetic detectives. Equipped with genomic sequencing technologies available for less than 10 years, these sleuths now routinely search through a patient's DNA looking for mutations responsible for mysterious diseases.

11 Aug 2017

Study shows that gene outside the brain controls ability to rebound from sleep deprivation

UCLA scientists report the first evidence that a gene outside the brain controls the ability to rebound from sleep deprivation -- a surprising discovery that could eventually lead to greatly improved treatments for insomnia and other sleep disorders that do not involve getting a drug into the brain.

11 Aug 2017

New version of gene editing technique corrects molecular mistakes in RNA-based diseases

Until recently, the CRISPR-Cas9 gene editing technique could only be used to manipulate DNA. In a 2016 study, University of California San Diego School of Medicine researchers repurposed the technique to track RNA in live cells in a method called RNA-targeting Cas9 (RCas9).

11 Aug 2017

Scientists create stem cell-based model of rare inherited neurological condition

An international team of scientists, led by University of California San Diego School of Medicine researchers, has created a human stem cell-based model of a rare, but devastating, inherited neurological autoimmune condition called Aicardi-Goutieres Syndrome (AGS).

11 Aug 2017

Xenotransplantation – organ transplants from animals may soon be a reality

Researchers have been able to create genetically modified piglets that are cleaned of the viruses that could causes diseases in humans. This could open up new avenues in organs transplants from pigs to humans. The process of transplanting organs or tissues from animals to humans is called xenotransplantation. The report was published this Tuesday in the journal Science.

11 Aug 2017

Desert lessons show how to survive severe dehydration that causes kidney injury

Millions of people die every year from dehydration as a result of exposure and illness. In humans, even the most minor dehydration can compromise the kidneys causing lifelong, irreparable issues or even death.

10 Aug 2017

Researchers identify gene that could play role in energy requirements of liver cancer cells

A little-studied gene may explain how some liver cancer cells obtain the nutrition they need to proliferate, according to new research from the University of Maryland.

10 Aug 2017

Researchers unravel genetic characteristics that increase risk of developing Tourette syndrome

An international research team including Vasiliy Ramensky, a member of the MIPT Life Sciences Center, has unraveled genetic characteristics that increase the risk of developing Tourette syndrome.

10 Aug 2017

Study demonstrates that genes could influence neural motor skills

Genes for many may be widely associated with determining certain traits and characteristics. Now a study co-led by John H. Martin of The CUNY School of Medicine at The City College of New York is demonstrating that they could also influence neural motor skills.

10 Aug 2017

Innovative handheld genetic sequencing device helps scientists track evolution of Zika virus

An international group of researchers on board a mobile laboratory equipped with an innovative handheld genetic sequencing device are tracking the movement of the Zika virus since it disembarked in Brazil and began spreading through the Americas.

From Oxford Nanopore Technologies 10 Aug 2017

Vitamin B3 supplementation during pregnancy may prevent birth defects, in-vivo study suggests

Supplementing the diet with vitamin B3 during pregnancy may treat the molecular deficiencies in women that can lead to birth defects, according to a landmark study in Australia. Over the last 12 years, developmental geneticist Sally Dunwoodie (Victor Chang Cardiac Research Institute, Sydney) and team have been studying the genes that influence fetal heart and bone development.

10 Aug 2017

Moffitt Cancer Center and Cvergenx form research partnership to revolutionize radiation therapy

Moffitt Cancer Center and Cvergenx announced a new research partnership that aims to revolutionize radiation therapy. The goal of the Future of Radiation Therapy project is to create a framework for using a patient's genetic information to provide a personalized radiation treatment plan.

9 Aug 2017

Genes News and Research

Study provides promising framework to anticipate drug resistance in cancer

Counteracting premature aging

Goldfish survive lack of oxygen for months by converting their carbs to alcohol

USC scientists obtain molecular 'how to' guide for growing hair

Duke researchers map evolution of sex chromosomes in fungus linked to human disease

Better analysis of kidney tumor samples

Experts highlight need to respect women's autonomy in prenatal testing

Feinstein researcher awarded NIH grant to better understand genetic causes of Alzheimer's disease

Researchers develop new technique to locate pathogenic mutations in dark, non-coding genome

Study shows that gene outside the brain controls ability to rebound from sleep deprivation

New version of gene editing technique corrects molecular mistakes in RNA-based diseases

Scientists create stem cell-based model of rare inherited neurological condition

Xenotransplantation – organ transplants from animals may soon be a reality

Desert lessons show how to survive severe dehydration that causes kidney injury

Researchers identify gene that could play role in energy requirements of liver cancer cells

Researchers unravel genetic characteristics that increase risk of developing Tourette syndrome

Study demonstrates that genes could influence neural motor skills

Innovative handheld genetic sequencing device helps scientists track evolution of Zika virus

Vitamin B3 supplementation during pregnancy may prevent birth defects, in-vivo study suggests

Moffitt Cancer Center and Cvergenx form research partnership to revolutionize radiation therapy

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