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Scientists discover how unusually long strands of RNA help colon cancer cells avoid death

Researchers from Case Western Reserve University School of Medicine have discovered how unusually long strands of RNA help colon cancer cells avoid death, allowing unregulated growth.

17 May 2018

New study could have important implications for cellular aging

Researchers have found a way to stimulate autophagy, a process used by cells to convert misfolded proteins and redundant organelles into components that the cell can re-use.

16 May 2018

Researchers demonstrate new strategy for stimulating autophagy

Brown University researchers studying the biology of aging have demonstrated a new strategy for stimulating autophagy, the process by which cells rebuild themselves by recycling their own worn-out parts.

16 May 2018

Researchers to explore how to prevent stress-related chronic pain conditions

More than 50 million people in the United States suffer from pain in the absence of injury. This includes patients with migraines, fibromyalgia, irritable bowel syndrome and many other disorders.

15 May 2018

Study uncovers promising new line of attack against aggressive prostate cancer

UC San Francisco researchers have discovered a promising new line of attack against lethal, treatment-resistant prostate cancer. Analysis of hundreds of human prostate tumors revealed that the most aggressive cancers depend on a built-in cellular stress response to put a brake on their own hot-wired physiology.

14 May 2018

Heart failure severity could vary based on the body's nitric oxide levels

The most common heart medications may get an assist from nitric oxide circulating in the body, according to a new study out of Case Western Reserve University School of Medicine.

14 May 2018

Researchers urge re-examination of colonial models in regulation of traditional medicine practitioners

Two commentaries in JACM, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers that is dedicated to examining paradigm, practice, and policy advancing integrative health, raise questions about whether the value to health care of traditional, complementary, and integrative practices and practitioners is unfairly de-valued by the dominant biomedical model.

14 May 2018

New case study shows CAR T therapy as viable option for AML patients

Chimeric Antigen Receptor T-cell therapy, also known as CAR T therapy, was named the biggest research breakthrough of 2017 by the American Society of Clinical Oncology. The personal gene therapy utilizes a patient's own immune cells to fight cancer.

9 May 2018

Johns Hopkins researchers identify protein clumps in diseased hearts

Similar to how protein clumps build up in the brain in people with some neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, protein clumps appear to accumulate in the diseased hearts of mice and people with heart failure, according to a team led by Johns Hopkins University researchers.

9 May 2018

Experts discuss how medicinal cannabis can impact opioid crisis

A multidisciplinary panel of experts discussed how medicinal cannabis can impact the opioid crisis, though clinical research to quantify this is difficult given strict federal laws

9 May 2018

New tool to track interactions among brain cells in action

It's a neuroscientist's dream: being able to track the millions of interactions among brain cells in animals that move about freely, behaving as they would under natural circumstances. New technology developed at The Rockefeller University represents a big step toward realizing that goal.

7 May 2018

Study shows advantages of using decellularized muscle to promote tissue regeneration

A new comparative study showed the advantages of using donor decellularized muscle to promote functional tissue regeneration at the site of bulk skeletal muscle loss due to trauma or surgery.

4 May 2018

Researchers discover how a light touch can lead to unbearable itching

For some people, particularly those who are elderly, even a light touch of the skin or contact with clothing can lead to unbearable itching.

4 May 2018

Stem cells cultured in vitro self-assemble into embryo

An embryo has been created in vitro from mouse stem cells cultured with a 3D scaffold. The resulting structure was remarkably similar to a natural mouse embryo.

3 May 2018

Researchers evaluate predictive value of stress testing and cardiac biomarkers in older women

Mayo Clinic researchers, reporting results of the SMART study, have shown that abnormal results on a stress electrocardiogram are an independent predictor of cardiovascular events such as heart attack, heart failure, hospitalization for chest pain, and death in perimenopausal or menopausal women.

2 May 2018

System designed to enable the control of animal cells using light

Scientists have developed a system of design principles for controlling cells, tissues or entire limbs using silicon-based photostimulation.

2 May 2018

Gene therapy offers potential cure for patients with lipoprotein lipase deficiency

During the first 18 months after treatment with ali-pogene tiparvovec, a gene therapy recently approved in Europe to treat lipoprotein lipase deficiency (LPLD), the first patient to receive the treatment had no abdominal pain or episodes of pancreatitis, following a history of 37 pancreatitis attacks.

2 May 2018

Researchers use CRISPR/Cas9 technique to turn off gene that regulates cholesterol levels in adult mice

Biomedical engineers at Duke University have used a CRISPR/Cas9 genetic engineering technique to turn off a gene that regulates cholesterol levels in adult mice, leading to reduced blood cholesterol levels and gene repression lasting for six months after a single treatment.

27 Apr 2018

Scientists work on erasable MRI contrast agents that can blink off on command

Magnetic resonance imaging, or MRI, is a widely used medical tool for taking pictures of the insides of our body.

26 Apr 2018

Hippo pathway plays essential role in embryonic development of the mouse heart

Using a technology that provides a 'high-resolution view' of the status of individual cells, a team of researchers has gained new insights into the embryonic development of the mouse heart.

24 Apr 2018