Progenitor Cells News and Research

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Jumping genes help detemine uniqueness of individual brains

Scientists at the Salk Institute for Biological Studies may have found one explanation for the puzzling variety in brain organization and function: mobile elements, pieces of DNA that can jump from one place in the genome to another, randomly changing the genetic information in single brain cells.

15 Jun 2005

US scientists find "mother of all brain stem cells"

Scientists at the University of Florida have been able grow brain cells in the laboratory.

14 Jun 2005

Researchers discover how microRNA are involved in the development of heart muscle

Researchers at UT Southwestern Medical Center have discovered how a small molecule of RNA called microRNA - a chemical cousin of DNA - helps fine tune the production of a key protein involved in the early development of heart muscle.

12 Jun 2005

New predictor for blood transplant success

The success of blood stem cell transplants used to treat diseases such as leukemia, Hodgkin’s lymphoma and aplastic anemia may soon become more predictable, thanks to a discovery made by researchers at the University of British Columbia.

11 May 2005

Research suggests potential new strategies for fighting age-related vascular disease

Declining function of cells that help repair the inner lining of blood vessels, known as endothelial progenitor cells, rather than a dwindling supply of the cells, may underlie the increased risk of atherosclerosis and other vascular diseases as people grow older, according to a new study (PDF) in the May 3, 2005, issue of the Journal of the American College of Cardiology.

4 May 2005

Researchers insert engineered human stem cells into the spinal cords of ALS-afflicted rats

Unveiling a delivery method that may one day help surgeons treat the deadly neurodegenerative disease amyotrophic lateral sclerosis (ALS), researchers at the University of Wisconsin-Madison have inserted engineered human stem cells into the spinal cords of ALS-afflicted rats.

19 Apr 2005

Discovery that sheds new light upon the growth and development of human natural killer (NK) cells

Scientists here have made a major discovery that sheds new light upon the growth and development of human natural killer (NK) cells, powerful but somewhat mysterious components of the body’s immune system that are the first line of defense against cancer and infectious diseases.

23 Mar 2005

ViaCell and Genzyme announce collaboration - ViaCell announces patent issuance

ViaCell and Genzyme Corporation announced today that the two companies entered into a collaboration related to diabetes.

15 Mar 2005

First evidence of cardiac progenitor cells

The first evidence of cardiac progenitor cells – rare, specialized stem cells located in the newborn heart of rats, mice and humans – has been shown by researchers at the University of California, San Diego (UCSD) School of Medicine. The cells are capable of differentiation into fully mature heart tissue.

10 Feb 2005

Scientists have coaxed human embryonic stem cells to become spinal motor neurons

After years of trial and error, scientists have coaxed human embryonic stem cells to become spinal motor neurons, critical nervous system pathways that relay messages from the brain to the rest of the body.

30 Jan 2005

Aastrom Biosciences responds to article regarding contaminated stem cell lines

Aastrom Biosciences responded today to the publication in the Sunday online edition of Nature Medicine of findings by California researchers that indicate that certain lines of human embryonic stem cells have been contaminated through the use of mice feeder cells.

25 Jan 2005

Research leads to new antiangiogenic drugs

Scientists have uncovered critical information that may lead to an urgently needed method for effective monitoring of antiangiogenic cancer therapies.

17 Jan 2005

Certain leukemia oncogenes switch on genetic programs that govern self-renewal, a unique stem cell characteristic

Researchers have discovered that specific cancer-causing genes associated with leukemias can transform mature white blood cells into leukemic cells that have all the properties of stem cells.

21 Dec 2004

Study finds new method can improve chemo survival

Seeking to find a way to lessen patients’ vulnerability to deadly infections following chemotherapy, researchers at the Stanford University School of Medicine have figured out a way to boost the immune function in animals following such treatments.

21 Dec 2004

Genetic mutations and cellular modifications may provide clues to the associations between slight genetic abnormalities and often fatal diseases

Modern research is delving deep into the human genome to find the answers to medical mysteries and, hopefully, cures for the most deadly diseases. According to four new studies presented during the 46th Annual Meeting of the American Society of Hematology

5 Dec 2004

Cellular vehicle delivers drugs directly into cancer cells

Researchers at The University of Texas M. D. Anderson Cancer Center have perfected a delivery system for anticancer treatment that zeroes in on a tumor and becomes part of its supporting tissue.

4 Nov 2004

Sperm cells grown in laboratory culture

A team of researchers working with cells from mice has overcome a technical barrier and succeeded in growing sperm progenitor cells in laboratory culture.

4 Nov 2004

Researchers suggest how to generate B cells from stem cells

Before stem cells, of whatever origin, can be used to treat patients, scientists will need to learn how to coax them to develop into the desired cell types, a major challenge.

11 Oct 2004

Stem cells from umbilical cord blood, given intravenously with mannitol drug reduce stroke size and damage

Researchers first gave the drug, mannitol, to provide temporary passage through the blood-brain barrier then transfused human umbilical cord blood cells into a stroke animal model. When used in the first hours and days following a stroke, stroke size decreased by 40 percent and resulting disability was significantly reduced.

26 Sep 2004

Scientists investigate the ability of heart muscle to repair itself

The scientists will investigate the ability of heart muscle to repair itself – after being damaged by a heart attack, for example – and to regain function.

6 Sep 2004