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Gut bacteria shown to affect statin efficacy in some people

The team led by a Duke University scientist has identified three bile acids produced by gut bacteria that were evident in people who responded well to a common cholesterol-lowering drug called simvastatin. The finding, published Oct. 13, 2011, in PLoS One, demonstrates how gut bacteria can cause inherent differences in the way people digest, metabolize and benefit from substances such as drugs.

17 Oct 2011

New series on child abuse on UBM Medica's Pediatrics Consultant Live

UBM Medica's Pediatrics Consultant Live has a new series called "Child Abuse–or Mimic?" which helps clinicians distinguish cases of child abuse from pediatric disease or mere accidents.

15 Oct 2011

UEI tool could allow doctors to deliver efficient, timely treatment for Crohn's disease

It's difficult for doctors to tell whether a patient with Crohn's disease has intestinal fibrosis, which requires surgery, or inflammation, which can be treated with medicine. A new imaging method might make that task easier, according to a U-M-led study.

15 Oct 2011

Researchers use online survey to examine drinking patterns and personality traits

Researchers used an anonymous online survey to examine drinking patterns and personality traits. Results identified three groups, two of which drank at fairly high levels. The group with higher levels of impulsivity and aggression appears most at-risk for future alcohol problems.

15 Oct 2011

New book on pediatric stroke and cerebrovascular diseases

Two decades after the first edition, a third edition of the definitive textbook on stroke in children -- Pediatric Stroke and Cerebrovascular Disorders -- has been published by Demos Medical Publishing of New York City.

15 Oct 2011

Lifestyle factors and nutritional patterns reduce early causes of childhood allergy

Today, about one in four European children suffer from allergy, which makes this disease the non-infectious epidemic of the 21st century. Evidence suggests that lifestyle factors and nutritional patterns, such as breastfeeding, help to reduce the early symptoms of allergy.

15 Oct 2011

Researchers identify gut bacteria bile acids linked to effectiveness of statin drugs in lowering cholesterol

Statins can be effective at lowering cholesterol, but they have a perplexing tendency to work for some people and not others. Gut bacteria may be the reason.

14 Oct 2011

NIH awards Scripps Research scientist for research into Type I diabetes

A scientist at The Scripps Research Institute has been awarded $4.2 million from the National Institutes of Health in a program to advance what the agency calls "bold and creative research" into Type I diabetes.

14 Oct 2011

WuXi PharmaTech announces acquisition of Abgent

WuXi PharmaTech Inc., a leading pharmaceutical, biotechnology and medical device research and development services company with operations in China and the United States, today announced the acquisition of Abgent, Inc., a provider of biological research reagent products and services based in Suzhou, China, and San Diego, California.

14 Oct 2011

InnaVirVax announces Phase I/IIa clinical trial authorization for its VAC-3S HIV vaccine

InnaVirVax, a biopharmaceutical company dedicated to the development of therapeutic and diagnostic solutions in pathologies associated with immune dysregulation, declared today that it has obtained authorization from the French drug agency (AFSSAPS) to start a Phase I/IIa clinical study of its therapeutic vaccine VAC-3S for the treatment of HIV infections. This authorization intervenes only two years and half after the launching of InnaVirVax’s activities.

14 Oct 2011

SFDA approves China Medical Technologies' colorectal cancer assay

China Medical Technologies, Inc., a leading China-based advanced in-vitro diagnostic company, today announced that China's State Food and Drug Administration has approved the Company's real-time PCR-based V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog assay as a companion diagnostic test for the use of a targeted drug for the treatment of colorectal cancer patients.

13 Oct 2011

Simmons Center to evaluate CGEN-25009 for treatment of idiopathic pulmonary fibrosis

Compugen Ltd. and the Pulmonary Fibrosis Foundation announced today that the Pulmonary Fibrosis Foundation will provide a grant to scientists at the University of Pittsburgh Dorothy P. and Richard P.

13 Oct 2011

AANEM Foundation strengthens and expands research initiatives

The AANEM Foundation for Research and Education has strengthened and expanded its research initiatives. It now will fund one $500,000 grant (up to $100,000 per year for 5 years).

13 Oct 2011

NanoString introduces nCounter Analysis System

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and developer of molecular diagnostics, today announced the launch of its second generation nCounter Analysis System.

From NanoString Technologies 13 Oct 2011

USPTO issues patent to Oragenics' In Vivo Induced Antigen Technology

Florida-based nutraceutical company, Oragenics, Inc., announced today the issuance of patent number 8,034,571 from the United States Patent and Trademark office for In Vivo Induced Antigen Technology.

13 Oct 2011

GeneDx launches new genetic test to accurately diagnose rare diseases

At the joint conference of the American Society of Human Genetics/International Congress on Human Genetics in Montreal on October 12, GeneDx, one of the foremost genetics laboratories in the world and a subsidiary of Bio-Reference Laboratories, Inc., is announcing a first-of-its-kind test that will enable physicians and patients to more accurately identify the genetic cause of rare diseases.

13 Oct 2011

A 'one-size-fits-all' approach to mental health leads to global 'diagnostic inflation'

In this Globalist opinion piece, Ian Dowbiggin, an author and professor of history at the University of Prince Edward Island in Canada, examines the issue of "diagnostic inflation" within the psychiatry field in the last half century and how, "as Ethan Watters and others have argued, lately American psychiatry has been exporting its diagnoses and treatments to other cultures, 'homogenizing how the world goes mad.'"

12 Oct 2011

Life Technologies launches Ion AmpliSeq Cancer Panel

Life Technologies Corporation today announced the launch of the Ion AmpliSeq Cancer Panel, enabling scientists to sequence dozens of genes in cancer research samples using a simple workflow.

12 Oct 2011

Two-gene DNA urine test for prostate cancer

In the current debate sparked by the recent USPSTF recommendation on PSA screening, it is clear that better biomarkers than PSA are urgently needed. One new biotechnology that may go a long way in detecting only prostate cancer and reducing unnecessary prostate cancer biopsies and possible subsequent overtreatment, is the development of a new urine test for prostate cancer.

12 Oct 2011

Chromosomal microarray can provide important information for patient treatment

Chromosomal microarray (CMA)—a powerful test for diagnosing the genetic abnormalities causing some types of developmental delay and birth defects—can be used in an evidence-based manner to provide important information for patient treatment, according to a pair of studies in the September issue of Genetics in Medicine, the official peer-reviewed journal of The American College of Medical Genetics.

12 Oct 2011