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Repurposed drug shows promise as potential new treatment for motor neuron disease

A drug typically used to treat enlarged prostates and high blood pressure has shown promise as a potential new therapy for motor neuron disease (MND), according to a new study.

11 Aug 2022

Interferon beta reduces binding of three components to RBCs, study finds

Drugs called interferon betas are common treatments for multiple sclerosis (MS), reducing relapses and slowing motor function decline. Interferon beta, a protein known to contain a zinc binding pocket, is thought to reduce proinflammatory molecules and even increase production of anti-inflammatory species in MS patients.

11 Aug 2022

Nearly three-quarters of all stem cell lines are affected by DNA damage, say researchers

DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say Cambridge researchers, who argue that whole genome sequencing is essential for confirming if cell lines are usable.

11 Aug 2022

Study quantifies the prognostic accuracy of two protein biomarkers

Blood tests taken within 24 hours of a traumatic brain injury (TBI) flag which patients are likely to die and which patients are likely to survive with severe disability, according to a study headed by UC San Francisco, the University of Pennsylvania and the University of Michigan. Their results -- available within minutes -- may confirm the need for prompt surgical interventions or may help guide conversations with families in cases of devastating injury.

11 Aug 2022

How ultraprocessed foods affect gut microbiome and health

Researchers describe the association between the consumption of ultraprocessed foods and chronic medical conditions.

10 Aug 2022

A low-energy, high FODMAP diet in prediabetes and diabetes?

Researchers summarize the available knowledge on FODMAPs and suggest that they can play a role in the prevention and treatment of diabetes.

10 Aug 2022

Older adults with atrial cardiopathy may have higher dementia risk

Older adults with atrial cardiopathy (a major, often undetected cardiac cause of stroke) may be at increased risk of developing dementia, according to new research led by Johns Hopkins Medicine.

10 Aug 2022

Blood-based biomarkers can accurately predict a patient's risk of death or disability after TBI

A study funded by the National Institutes of Health found that biomarkers present in the blood on the day of a traumatic brain injury (TBI) can accurately predict a patient's risk of death or severe disability six months later.

10 Aug 2022

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

A monoclonal antibody, mepolizumab, decreased asthma attacks by 27% in Black and Hispanic children and adolescents who have a form of severe asthma, are prone to asthma attacks and live in low-income urban neighborhoods, a National Institutes of Health clinical trial has found.

10 Aug 2022

Abnormal size or functioning in the heart's left atrium may increase dementia risk

Structural or functional abnormalities within the heart's left atrium, with or without symptoms, may increase a person's risk of developing dementia later in life by 35%, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

10 Aug 2022

How much plastic was used during the COVID-19 pandemic?

In a new study, researchers estimated the amount of plastic required in a SARS-CoV-2 diagnostic assay.

10 Aug 2022

Review of natural products with promising anti-SARS-CoV-2 potential

In a new study, researchers reviewed existing literature on naturally active products with therapeutic efficacy against SARS-CoV-2.

10 Aug 2022

Experimental drug protects mice from sudden death due to blood vessel rupture

An experimental drug therapy protects mice from sudden death due to the rupture of a major blood vessel in the abdomen, according to a study from researchers at Washington University School of Medicine in St. Louis.

10 Aug 2022

How common is chronic fatigue syndrome among patients with long COVID-19?

In a new study, researchers found that myalgic encephalitis/chronic fatigue syndrome (ME/CFS) was common in long COVID-19.

10 Aug 2022

EPA action boosts grassroots momentum to reduce toxic ‘forever chemicals’

The intake pumps that once drew 6 million gallons of water a day from the Oostanaula River now sit mostly dormant in this northwestern Georgia city.

10 Aug 2022

Study evaluates two immunization schedules for the inactivated SARS-CoV-2 vaccine Coronavac

Researchers conducted phase 3 evaluations of the immunogenicity of the two immunization timeframes of the CoronaVac COVID-19 vaccine among Chilean adults.

10 Aug 2022

Study shows how the same protein that is key for brain development can also be the cause for the spread of cancer

Researchers at Queen's University Belfast have revealed how the pathway of an identified protein could lead to early diagnosis and targeted treatment for several cancers and brain disorders.

10 Aug 2022

IRB scientists identify critical spots on the genome where gene editing could cause an unwanted response

CRISPR/Cas9 is a commonly used, very precise, gene editing technique whose development, by Jennifer A. Doudna and Emmanuelle Charpentier, was recognised with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors", CRISPR allows the introduction of the desired DNA sequence into (virtually) any spot of the genome, thus modifying or inactivating a gene. This technique is widely used in biomedical research and some CRISPR-based therapies are in clinical trials for the treatment of human blood disorders, some types of cancer and HIV, among other conditions.

10 Aug 2022

Researchers collaborate on a 15-month case study to analyze patient’s recovery from impaired adrenocorticotropic hormone

Recently, 'Long COVID' is becoming a significant issue worldwide. It refers to a variety of symptoms that persist over an extended period after the patient has recovered from a novel coronavirus infection (COVID-19). In many cases, it is unclear what causes Long COVID symptoms, and there is insufficient information regarding recovery time.

10 Aug 2022

Next-generation sequencing system yields results comparable to traditional diagnostics

In the pursuit of accurate diagnoses for illnesses, doctors have traditionally used multiple methods — including culturing patient samples on a wide variety of media, reviewing countless medical records and analyzing clinical data using complex mathematical algorithms — to try to identify the bacterium, virus, fungus or other pathogen responsible for an infection.

10 Aug 2022

Blood News and Research

Repurposed drug shows promise as potential new treatment for motor neuron disease

Interferon beta reduces binding of three components to RBCs, study finds

Nearly three-quarters of all stem cell lines are affected by DNA damage, say researchers

Study quantifies the prognostic accuracy of two protein biomarkers

How ultraprocessed foods affect gut microbiome and health

A low-energy, high FODMAP diet in prediabetes and diabetes?

Older adults with atrial cardiopathy may have higher dementia risk

Blood-based biomarkers can accurately predict a patient's risk of death or disability after TBI

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

Abnormal size or functioning in the heart's left atrium may increase dementia risk

How much plastic was used during the COVID-19 pandemic?

Review of natural products with promising anti-SARS-CoV-2 potential

Experimental drug protects mice from sudden death due to blood vessel rupture

How common is chronic fatigue syndrome among patients with long COVID-19?

EPA action boosts grassroots momentum to reduce toxic ‘forever chemicals’

Study evaluates two immunization schedules for the inactivated SARS-CoV-2 vaccine Coronavac

Study shows how the same protein that is key for brain development can also be the cause for the spread of cancer

IRB scientists identify critical spots on the genome where gene editing could cause an unwanted response

Researchers collaborate on a 15-month case study to analyze patient’s recovery from impaired adrenocorticotropic hormone

Next-generation sequencing system yields results comparable to traditional diagnostics

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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