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Metabolite discovery offers a potential way to address metabolic conditions

"Metabolism" describes the body's chemical changes that create the necessary materials for growth and overall health. Metabolites are the substances made and used during these metabolic processes - or, as a new discovery out of Scripps Research and its drug development arm, Calibr, indicates, they could also be potent molecules for treating severe diseases.

13 Oct 2022

New technology for producing oxygen within cells

Oxygen is vital for life, and clinicians can provide supplemental oxygen to patients through face masks and nasal tubes, but there are no methods available for delivering oxygen directly into cells.

13 Oct 2022

Largest academic collaboration aims to transform the treatment for pediatric cancers

The Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute and St. Jude Children's Research Hospital today announced the largest academic collaboration of its kind to transform and accelerate the identification of vulnerabilities in pediatric cancers and translate them into better treatments.

13 Oct 2022

Changes in the skin microbiome may contribute to development of GVHD after stem cell transplant

Organ damage occurs in up to 70 percent of patients in the first few months following stem cell transplant. The precise reasons for this potentially life-threatening reaction have long been the subject of scientific research.

13 Oct 2022

Study finds memory B cell clones harbor the capacity to adopt multiple and functionally different fates in COVID-19 patients

Researchers examined single clones of SARS-CoV-2-specific memory B cells to understand their adaptability and fate.

13 Oct 2022

Motif-based SARS-CoV-2 protein-human protein interactions as potential antiviral target sites

Researchers performed a ProP-PD (proteomic peptide phage display) analysis to identify peptides from intrinsically disordered human (host) proteome regions that bind with SARS-CoV-2 genome-encoded folded protein domains (PDs).

13 Oct 2022

New partnership creates an automated anatomic pathology slide-scanning solution

Sakura Finetek, a global leader in histopathology products and Evident Scientific, a wholly owned subsidiary of Olympus Corporation, and a global leader in microscopy and imaging solutions, today announced a collaboration to offer a full workflow solution for anatomic pathology slide preparation and high-resolution digital scanning in the Americas.

From Evident Corporation - Life Sciences 13 Oct 2022

What is the association between interferon genes and complement regulatory protein expressions in SARS-CoV-2 infections?

Researchers investigated the expression of complement regulatory proteins (CRPs) in coronavirus disease 2019 (COVID-19) to identify potential dysregulated CRP patterns and investigate whether they contribute to COVID-19 pathogenesis.

13 Oct 2022

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

A new study aimed to analyze the immunometalobism BALF cells from mild to severe COVID-19 patients using computational algorithms that quantified metabolic fluxes and metabolic pathways.

13 Oct 2022

Understanding the potential applications of stem cell research

To mark Stem Cell Awareness Day on October 12, 2022, COST is highlighting a network of researchers working to foster greater understanding about stem cell research and potential applications for millions of people suffering from incurable diseases and injury.

12 Oct 2022

Advanced cryo-electron microscope reveals how poliovirus takes over human cells

For the first time, researchers at Umeå University, Sweden, can now show how the dreaded poliovirus behaves when it takes over an infected cell and tricks the cell into producing new virus particles.

12 Oct 2022

Clinical trial to evaluate antiviral drug for monkeypox begins in the Democratic Republic of the Congo

A clinical trial to evaluate the antiviral drug tecovirimat, also known as TPOXX, in adults and children with monkeypox has begun in the Democratic Republic of the Congo (DRC).

12 Oct 2022

Mic60-low gene signature may be a simple tool to estimate pancreatic cancer risk

The mitochondria is a key energy-producing component of the human cell that plays an important role in cancer cell metabolism.

12 Oct 2022

Study shows a new avenue of assessing muscle strength

Muscular strength and its improvement are important to everyone for their regular day-to-day life activities.

12 Oct 2022

Study sheds new light on host-pathogen interactions and long-term consequences of brain infections

A team led by Prof Kiavash Movahedi has mapped in detail how the immune system acts against pathogens invading the brain.

12 Oct 2022

Scientists show how cellular hypoxia response increases fetal hemoglobin expression in adults

Scientists at St. Jude Children's Research Hospital have shown how a protein responsible for adapting to low oxygen conditions (hypoxia), causes increased expression of fetal hemoglobin (HbF) in adults.

12 Oct 2022

Exercise can favorably modify subcutaneous adipose tissue that can improve metabolic health

Exercise is one of the first strategies used to treat obesity-related health problems like Type 2 diabetes and other cardiovascular disease, but scientists don’t understand exactly how it works to improve metabolic health.

12 Oct 2022

Study explores cell signaling dysregulation and COVID-19 severity

Researchers assessed the impact of dysregulation in cell signaling events on coronavirus disease 2019 (COVID-19) severity.

12 Oct 2022

New method allows for a much more detailed examination of the brain processes

Scientists have developed a research method that allows for a much more detailed examination of the brain processes involved in some neurological and mental disorders.

12 Oct 2022

Research shows how a very low dose of rhenium metal complex kills ovarian cancer cells

Metal-containing complexes have taken up center stage in the search for new cancer drugs that are as free of side effects as possible.

12 Oct 2022

Cell News and Research

Metabolite discovery offers a potential way to address metabolic conditions

New technology for producing oxygen within cells

Largest academic collaboration aims to transform the treatment for pediatric cancers

Changes in the skin microbiome may contribute to development of GVHD after stem cell transplant

Study finds memory B cell clones harbor the capacity to adopt multiple and functionally different fates in COVID-19 patients

Motif-based SARS-CoV-2 protein-human protein interactions as potential antiviral target sites

New partnership creates an automated anatomic pathology slide-scanning solution

What is the association between interferon genes and complement regulatory protein expressions in SARS-CoV-2 infections?

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

Understanding the potential applications of stem cell research

Advanced cryo-electron microscope reveals how poliovirus takes over human cells

Clinical trial to evaluate antiviral drug for monkeypox begins in the Democratic Republic of the Congo

Mic60-low gene signature may be a simple tool to estimate pancreatic cancer risk

Study shows a new avenue of assessing muscle strength

Study sheds new light on host-pathogen interactions and long-term consequences of brain infections

Scientists show how cellular hypoxia response increases fetal hemoglobin expression in adults

Exercise can favorably modify subcutaneous adipose tissue that can improve metabolic health

Study explores cell signaling dysregulation and COVID-19 severity

New method allows for a much more detailed examination of the brain processes

Research shows how a very low dose of rhenium metal complex kills ovarian cancer cells

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