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Using native microbes as chassis for transgene delivery in live bacterial therapeutics

Residing within the human gut are trillions of bacteria and other microorganisms that can impact a variety of chronic human ailments, including obesity, type 2 diabetes, atherosclerosis, cancer, non-alcoholic fatty liver disease and inflammatory bowel disease.

4 Aug 2022

Monoclonal antibody protects U.S. adults from malaria, Phase 1 clinical trial shows

One injection of a candidate monoclonal antibody (mAb) known as L9LS was found to be safe and highly protective in U.S. adults exposed to the malaria parasite, according to results from a National Institutes of Health Phase 1 clinical trial published in The New England Journal of Medicine.

4 Aug 2022

New easy-to-use test could rapidly diagnose heart attacks and cancers

Imperial researchers have built a new easy-to-use test that could diagnose non-infectious diseases like heart attacks and cancers more quickly.

4 Aug 2022

Higher suPAR levels linked with increased risk of blood clot formation

Blood clots are thought to occur in as many as a third of patients hospitalized with COVID-19. In many cases these clots can be deadly, such as pulmonary embolisms - blood clots that travel to the lungs. In fact, in nearly one third of patients with COVID-19, these clots led to death.

4 Aug 2022

Mice study reveals hepatic consequences of exposure to endocrine disrupting chemical mixtures

We are increasingly being exposed to endocrine-disrupting chemicals (EDCs) that interfere with the normal functioning of our hormones. Bisphenol A (BPA) and phthalates, which are widely used in consumer products including plastics, aluminum cans, pharmaceuticals, and cosmetics, are well-known EDCs.

4 Aug 2022

Disease progression in the rhesus macaque model upon inoculation with the Delta, Omicron BA.1, and Omicron BA.2 variants

Researchers compared the severity levels of disease caused by different SARS-CoV-2 variants of concern in the rhesus macaque model.

4 Aug 2022

Fully reduced form of vitamin K found to efficiently inhibit ferroptotic cell death

A team of researchers at Tohoku University has reported on a novel function of vitamin K, which is generally known for its importance in blood clotting.

4 Aug 2022

Can high-dose coenzyme Q10 reduce the number and severity of post-COVID-19 condition-related symptoms?

Investigators assessed the potential of high-dose coenzyme Q10 treatment for long coronavirus disease.

4 Aug 2022

Study uses digital technology to evaluate antibody response following COVID-19 boosters

Researchers conducted an observational trial in the United States during the SARS-CoV-2 Omicron wave.

4 Aug 2022

New study uncovers a likely proteome signature for reductive stress cardiomyopathy

Two years ago, University of Alabama at Birmingham researchers and colleagues reported that reductive stress - an imbalance in the normal oxidation/reduction, or redox, homeostasis - caused pathological changes associated with heart failure in a mouse model.

3 Aug 2022

Study: Genes involved in coronary heart disease may be nearly the same for everyone

The genes involved in coronary heart disease, the most common form of heart disease, appear to be nearly the same for everyone, according to a VA study.

3 Aug 2022

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

Investigators from Cedars-Sinai Cancer have identified genetic signatures that could predict whether tumors in patients with bladder and other cancers will respond to immunotherapy.

3 Aug 2022

Older age and smoking linked to increased risk of developing any cancer, study shows

A new large study led by researchers at the American Cancer Society (ACS) shows older age and smoking are the two most important risk factors associated with a relative and absolute five-year risk of developing any cancer.

3 Aug 2022

UVA researchers receive $15 million from LeDucq Foundation to advance understanding of atherosclerosis

The Boston-based LeDucq Foundation has awarded $15 million to researchers at UVA Health and their collaborators to advance our understanding of atherosclerosis, or hardening of the arteries, and find better ways to treat it.

3 Aug 2022

Women with a history of hypertensive disorders of pregnancy more likely to develop dementia

Hypertensive disorders of pregnancy (HDP) — conditions of high blood pressure including chronic/gestational hypertension and preeclampsia — have been strongly linked to heart disease in later life, but, before today, little research has connected these disorders with cognition.

3 Aug 2022

Women with a history of preeclampsia have increased markers of brain cell damage, inflammation

How do the rates of SARS-CoV-2 shedding into exhaled breath aerosol differ between individuals infected by different variants?

A recent article analyzed the SARS-CoV-2 shedding evolution in exhaled breath aerosols.

3 Aug 2022

Blood News and Research

Using native microbes as chassis for transgene delivery in live bacterial therapeutics

Monoclonal antibody protects U.S. adults from malaria, Phase 1 clinical trial shows

New easy-to-use test could rapidly diagnose heart attacks and cancers

Higher suPAR levels linked with increased risk of blood clot formation

Mice study reveals hepatic consequences of exposure to endocrine disrupting chemical mixtures

Disease progression in the rhesus macaque model upon inoculation with the Delta, Omicron BA.1, and Omicron BA.2 variants

Fully reduced form of vitamin K found to efficiently inhibit ferroptotic cell death

Can high-dose coenzyme Q10 reduce the number and severity of post-COVID-19 condition-related symptoms?

Study uses digital technology to evaluate antibody response following COVID-19 boosters

New study uncovers a likely proteome signature for reductive stress cardiomyopathy

Study: Genes involved in coronary heart disease may be nearly the same for everyone

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

Older age and smoking linked to increased risk of developing any cancer, study shows

UVA researchers receive $15 million from LeDucq Foundation to advance understanding of atherosclerosis

Women with a history of hypertensive disorders of pregnancy more likely to develop dementia

Women with a history of preeclampsia have increased markers of brain cell damage, inflammation

Memory B and T cell responses to the SARS-CoV-2 spike protein before and after the third BNT162b2 booster

Researchers assess Alzheimer's disease risk and anti-diabetic drugs

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

How do the rates of SARS-CoV-2 shedding into exhaled breath aerosol differ between individuals infected by different variants?

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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