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Scientists discover how MRP-14 gene generates dangerous clots that could trigger heart attack

Right now, options are limited for preventing heart attacks. However, the day may come when treatments target the heart attack gene, myeloid related protein-14 (MRP-14, also known as S100A9) and defang its ability to produce heart attack-inducing blood clots, a process referred to as thrombosis.

2 Apr 2014

Low levels of sodium prior to liver transplantation do not increase risk of death, say researchers

Researchers report that low levels of sodium, known as hyponatremia, prior to transplantation does not increase the risk of death following liver transplant. Full findings are published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

2 Apr 2014

Excessive occupancy levels in hospitals increases risk of mortality of critically ill patients

Once a hospital reaches a certain occupancy level, the quality of care it provides deteriorates, increasing the risk of mortality of critically ill patients. What is worrying is that this safety 'tipping point' is reached at occupancy levels that are below 100%.

1 Apr 2014

Bayer’s Adempas now available in the UK to treat patients with CTEPH

Adempas (riociguat) is available in the UK today as the first drug treatment for CTEPH, to treat adult patients with WHO Functional Class (FC) II to III with inoperable or persistent disease to improve exercise capacity.

1 Apr 2014

Research uncovers link between diet and blood cell markers of heart attack associated inflammation

New research further illuminates the heart-healthy benefits of the Mediterranean diet, tying the eating plan to lower levels of platelets and white blood cells, two markers of inflammation. Inflammation has an association with greater risk of heart attack and stroke.

1 Apr 2014

Clonidine increases hypotension and non-fatal cardiac arrest after noncardiac surgery

Clonidine - a drug that reduces blood pressure and heart rate - increased rates of clinically concerning hypotension and non-fatal cardiac arrest after noncardiac surgery, according to the POISE-2 trial presented at the American College of Cardiology's 63rd Annual Scientific Session.

1 Apr 2014

rEVO Biologics commences ATryn Phase 3 clinical program for treatment of preeclampsia in pregnant women

rEVO Biologics Inc., a subsidiary of LFB SA, today announced the initiation of the Phase 3 clinical program for ATryn for the treatment of preeclampsia in pregnant women during the 24th to 28th week of pregnancy.

31 Mar 2014

New study shows anti-anxiety drugs and sleeping pills associated with increased risk of death

Anti-anxiety drugs and sleeping pills have been linked to an increased risk of death, according to new research from the University of Warwick.

31 Mar 2014

SEATTLE II study confirms safety and efficacy of thrombolytic therapy for acute PE

EKOS Corporation, a BTG International group company, notes the presentation of the results of the SEATTLE II trial this afternoon at ACC.14, the 63rd Annual Scientific Session and Exposition of the American College of Cardiology in Washington, DC in the United States.

31 Mar 2014

Cheap drug holds promise of treating heart attack patients

The initial results of this trial were published a few months ago (Circulation. 2013;128:1495-1503), and showed that patients who received this treatment during emergency transit to hospital had much smaller amounts of dead heart muscle than those randomly assigned to receive no treatment.

31 Mar 2014

MADIT-CRT study: Boston Scientific CRT defibrillator reduces risk of death in mild heart failure patients

In the longest follow-up to date of cardiac resynchronization therapy (CRT) for mild heart failure patients, Boston Scientific Corporation's exclusively sponsored and landmark Multicenter Automatic Defibrillator Implantation Trial – Cardiac Resynchronization Therapy (MADIT-CRT) study demonstrated significant and sustained survival benefit for the indicated population.

31 Mar 2014

Study compares two types of heart valve technologies

Among patients undergoing aortic valve replacement using a catheter tube, a comparison of two types of heart valve technologies, balloon-expandable or self-expandable valve systems, found a greater rate of device success with the balloon-expandable valve, according to a JAMA study released online to coincide with presentation at the 2014 American College of Cardiology Scientific Sessions.

31 Mar 2014

Women who drink too many diet drinks a day more likely to have heart problems

It appears healthy postmenopausal women who drink two or more diet drinks a day may be more likely to have a heart attack, stroke or other cardiovascular problems, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

31 Mar 2014

Methodist Healthcare to receive Texas Award for Performance Excellence from Quality Texas Foundation

Methodist Healthcare has been selected to receive the Texas Award for Performance Excellence (TAPE) from the Quality Texas Foundation, representing the highest level of quality an organization can achieve in the state of Texas. Methodist Healthcare is the first and only health care system in South Texas and the third organization in San Antonio to receive the TAPE award since the inception of the award in 1994.

29 Mar 2014

Study: Repeat sternotomy for surgical aortic valve replacement safe for octogenarian patients

Surgical aortic valve replacement generally improves patients' symptoms and prolongs survival. However, the perceived risk of surgical aortic valve replacement in patients over 80 may result in surgery being denied or a recommendation for alternative therapy. Investigators at the Mayo Clinic challenge the way these patients have been managed.

29 Mar 2014

New angiographic analysis examines impact of stent thrombosis in patients undergoing PCI

A new angiographic analysis of the CHAMPION PHOENIX trial examined the incidence and impact of stent thrombosis (ST) in patients undergoing percutaneous coronary intervention (PCI). Results of the study were released today and will be presented March 30 at the American College of Cardiology 63rd Annual Scientific Session.

29 Mar 2014

Two doses of HPV-16/18 AS04-adjuvanted vaccine Cervarix non-inferior to three-doses

A recent study in the journal Human Vaccines & Immunotherapeutics, showed that two doses of the HPV-16/18 AS04-adjuvanted vaccine Cervarix (GlaxoSmithKline) are non-inferior to three-doses in the current schedule.

29 Mar 2014

Takeda to present results from global EXAMINE CV safety outcomes trial at ACC 2014

Takeda Pharmaceuticals Company Limited will present sub-analyses from the global EXAMINE (EXamination of CArdiovascular OutcoMes: AlogliptIN vs. Standard of CarE in Patients with Type 2 Diabetes Mellitus and Acute Coronary Syndrome) cardiovascular (CV) safety outcomes trial in a poster session at the American College of Cardiology’s 63rd Annual Scientific Session in Washington, DC.

28 Mar 2014

Heart attack survival rates lag behind in the South despite overall improvements nationwide

Although heart attack death has declined across all regions of the United States, it is proportionately higher in the South, possibly related to the uneven distribution of socioeconomic and traditional cardiovascular risk factors, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

CDC identifies six new cases of people with Heartland virus

The Centers for Disease Control and Prevention in collaboration with health officials in Missouri and Tennessee have identified six new cases of people sick with Heartland virus: five in Missouri and one in Tennessee. The new cases, discovered in 2012 and 2013, are described today in CDC's Morbidity and Mortality Weekly Report.

28 Mar 2014

Mortality News and Research

Scientists discover how MRP-14 gene generates dangerous clots that could trigger heart attack

Low levels of sodium prior to liver transplantation do not increase risk of death, say researchers

Excessive occupancy levels in hospitals increases risk of mortality of critically ill patients

Bayer’s Adempas now available in the UK to treat patients with CTEPH

Research uncovers link between diet and blood cell markers of heart attack associated inflammation

Clonidine increases hypotension and non-fatal cardiac arrest after noncardiac surgery

rEVO Biologics commences ATryn Phase 3 clinical program for treatment of preeclampsia in pregnant women

New study shows anti-anxiety drugs and sleeping pills associated with increased risk of death

SEATTLE II study confirms safety and efficacy of thrombolytic therapy for acute PE

Cheap drug holds promise of treating heart attack patients

MADIT-CRT study: Boston Scientific CRT defibrillator reduces risk of death in mild heart failure patients

Study compares two types of heart valve technologies

Women who drink too many diet drinks a day more likely to have heart problems

Methodist Healthcare to receive Texas Award for Performance Excellence from Quality Texas Foundation

Study: Repeat sternotomy for surgical aortic valve replacement safe for octogenarian patients

New angiographic analysis examines impact of stent thrombosis in patients undergoing PCI

Two doses of HPV-16/18 AS04-adjuvanted vaccine Cervarix non-inferior to three-doses

Takeda to present results from global EXAMINE CV safety outcomes trial at ACC 2014

Heart attack survival rates lag behind in the South despite overall improvements nationwide

CDC identifies six new cases of people with Heartland virus

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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