Genes News and Research

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UT Southwestern researchers uncover mechanism linked to balding and hair graying

UT Southwestern Medical Center researchers have identified the cells that directly give rise to hair as well as the mechanism that causes hair to turn gray - findings that could one day help identify possible treatments for balding and hair graying.

9 May 2017

Study reveals role of good-guy protein in initiating and maintaining cancer

Under normal conditions, the CHD4 protein is one of the good guys: it stops cells from transcribing faulty DNA, thereby eliminating potential mutation. But in colon cancer and perhaps other kinds of cancer as well, it appears that this protein becomes a kind of double agent, working for the enemy.

9 May 2017

UTHealth study reveals genetic markers linked to increased risk for bipolar disorder in children

Genetic alterations that can be modulated by stress have been identified in children at high risk for bipolar disorder, according to a recently published study by researchers at McGovern Medical School at The University of Texas Health Science Center at Houston.

8 May 2017

Choice of fat causes distinct epigenetic changes in human adipose tissue, study shows

Previous research has demonstrated that saturated fat is more fattening and less muscle building than polyunsaturated fats. A new study shows that the choice of fat causes epigenetic changes which in turn could contribute to differences in fat storage.

8 May 2017

Study uncovers potential new therapeutic targets for HCV infections

An international study led by researchers at Monash University' Biomedicine Discovery Institute (BDI) has shone light on the way the Hepatitis C Virus (HCV) hijacks the communication systems in the host cells it infects, uncovering potential new therapeutic targets for the disease.

8 May 2017

Study shows how influenza A hijacks human cellular machinery to replicate

Much is known about flu viruses, but little is understood about how they reproduce inside human host cells, spreading infection. Now, a research team headed by investigators from the Icahn School of Medicine at Mount Sinai is the first to identify a mechanism by which influenza A, a family of pathogens that includes the most deadly strains of flu worldwide, hijacks cellular machinery to replicate.

5 May 2017

Novel approach cures diabetes in mice for one year without side effects

A potential cure for Type 1 diabetes looms on the horizon in San Antonio, and the novel approach would also allow Type 2 diabetics to stop insulin shots.

5 May 2017

Scientists identify RIOK1 enzyme as new target for cancer therapy

Dr. Florian Weinberg, from Prof. Dr. Tilman Brummer's research group at the Institute of Molecular Medicine and Cell Research of the University of Freiburg, joined forces with scientists from the Departments of Clinical Pathology and Medicine I of the University Medical Centre Freiburg and the Kinghorn Cancer Centre/Garvan Insitute in Australia in an international team that has identified a new target for cancer therapy.

5 May 2017

Novel signal-processing tool enables unbiased, data-driven analysis of ultrasonic vocalizations

Vocalization plays a significant role in social communication across species such as speech by humans and song by birds. Male mice produce ultrasonic vocalizations in the presence of females and both sexes sing during friendly social encounters.

5 May 2017

New conference aims to improve understanding of how advances in genomics influence society

From prenatal genetic screening to the genetic testing of women with family histories of breast cancer, genomics is rapidly becoming a fixture in our lives.

5 May 2017

Genetic study outlines path to personalize breast cancer risk assessment and treatment

Although the odds of developing breast cancer are nearly identical for black and white women, black women are 42 percent more likely to die from the disease. This mortality gap – driven by social and environmental, as well as biological factors – continues to persist.

4 May 2017

Molecular mechanism reprograms tumor cells to drive treatment resistance in advanced prostate cancer

Columbia University Medical Center researchers have discovered a molecular mechanism that reprograms tumor cells in patients with advanced prostate cancer, reducing their response to anti-androgen therapy.

4 May 2017

International consensus addresses research bottlenecks to diagnose rare genetic diseases

A worldwide consensus co-authored by more than 40 scientists sets out ways to address research bottlenecks as the international community strives to diagnose most rare genetic diseases by 2020.

4 May 2017

American Cancer Society awards new $792,000 grant to Yale researcher

The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has approved funding of a new research grant totaling $792,000 to a researcher at Yale University.

4 May 2017

Scientists uncover thousands of human genes that are expressed differently in the two sexes

Men and women differ in obvious and less obvious ways -- for example, in the prevalence of certain diseases or reactions to drugs. How are these connected to one's sex? Weizmann Institute of Science researchers recently uncovered thousands of human genes that are expressed -- copied out to make proteins -- differently in the two sexes.

4 May 2017

Disrupting the circadian clock can alter gut microbiome and the body's response to diet

Researchers at Baylor College of Medicine have discovered that changing the circadian clock in mouse liver can alter how the body responds to diet and also change the microbes living in the digestive track.

4 May 2017

New drug mimics health effects of exercise, say researchers

Scientists have managed to mimic the health effects of exercise in mice, simply by using a pill, according to a study published in Cell Metabolism. The drug activated a genetic pathway that is triggered by running, which led mice to burn off more fat and increase their stamina levels, despite them being sedentary.

4 May 2017

Study shows first removal of HIV-1 replication using CRISPR/Cas9, gene editing technology

A new study published in the journal Molecular Therapy reveals that HIV DNA in the genome of living animals can be removed to eliminate further infection. While a permanent cure for infection caused by HIV remains a challenge due to the ability of the virus to hide away in latent reservoirs. The study team comprising Wenhui Hu, Kamel Khalili, Laura H. Carnell, and Won-Bin Young carried out an experiment on three different animal models.

4 May 2017

Gene mutation may accelerate loss of memory and thinking skills in people with Alzheimer's risk

A gene mutation may accelerate the loss of memory and thinking skills in people who are at risk for Alzheimer's disease, according to a study published in the May 3, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology. The gene mutation is called the BDNF Val66Met allele, or just the Met allele.

4 May 2017

Synthetic biologists re-engineer yeast cells to manufacture antibiotic penicillin

The synthetic biologists from Imperial College London have re-engineered yeast cells to manufacture the nonribosomal peptide antibiotic penicillin. In laboratory experiments, they were able to demonstrate that this yeast had antibacterial properties against streptococcus bacteria.

4 May 2017

Genes News and Research

UT Southwestern researchers uncover mechanism linked to balding and hair graying

Study reveals role of good-guy protein in initiating and maintaining cancer

UTHealth study reveals genetic markers linked to increased risk for bipolar disorder in children

Choice of fat causes distinct epigenetic changes in human adipose tissue, study shows

Study uncovers potential new therapeutic targets for HCV infections

Study shows how influenza A hijacks human cellular machinery to replicate

Novel approach cures diabetes in mice for one year without side effects

Scientists identify RIOK1 enzyme as new target for cancer therapy

Novel signal-processing tool enables unbiased, data-driven analysis of ultrasonic vocalizations

New conference aims to improve understanding of how advances in genomics influence society

Genetic study outlines path to personalize breast cancer risk assessment and treatment

Molecular mechanism reprograms tumor cells to drive treatment resistance in advanced prostate cancer

International consensus addresses research bottlenecks to diagnose rare genetic diseases

American Cancer Society awards new $792,000 grant to Yale researcher

Scientists uncover thousands of human genes that are expressed differently in the two sexes

Disrupting the circadian clock can alter gut microbiome and the body's response to diet

New drug mimics health effects of exercise, say researchers

Study shows first removal of HIV-1 replication using CRISPR/Cas9, gene editing technology

Gene mutation may accelerate loss of memory and thinking skills in people with Alzheimer's risk

Synthetic biologists re-engineer yeast cells to manufacture antibiotic penicillin

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