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Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

In a new study, a team of researchers explored the effect of immune checkpoint blockade (ICB)-induced expansion of age-associated B cells (ABCs) on COVID-19 vaccine-derived humoral immunity in patients with cancer and inborn errors of immunity (IEI).

22 Sep 2022

New board members bring significant leadership experience in the biotech sector

Aspect Biosystems, a biotechnology company pioneering the development of bioprinted tissue therapeutics to transform how we treat disease, is pleased to announce the appointment of three new members to its Board of Directors: Dr. Nancy Krieger, Dr. Don Haut, and Dr. Devyn Smith.

From Aspect Biosystems 22 Sep 2022

Scientists uncover key details of an immune-cell process that underlies excessive inflammation

A team led by Scripps Research scientists has uncovered key details of an immune-cell process that frequently underlies excessive inflammation in the body.

22 Sep 2022

New modeling system identifies potential therapeutics for autosomal recessive polycystic kidney disease

Organoids - lab grown cells or tissues that resemble organs - serve as a new tool for disease modeling, but researchers often have difficulty replicating the biophysical conditions in which the organs operate within the body.

22 Sep 2022

Deep mutational scanning for SARS-CoV-2 Omicron BA.1 and BA.2 subvariants

Researchers performed deep mutational scanning for the SARS-CoV-2 Omicron variant of concern sub-VOC BA.1 and BA.2 receptor-binding domains.

22 Sep 2022

All SARS-CoV-2 variants blocked by a simple peptide with nanomolar neutralizing efficacy

In a recent study published in the journal PNAS, researchers from Finland and the United States reported a novel heptad repeat 2 (HR2) peptide that inhibited severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) without any chemical modifications.

21 Sep 2022

Mount Sinai researchers use unbiased AI-based method to study the causes of cognitive impairment

Mount Sinai researchers have used novel artificial intelligence methods to examine structural and cellular features of human brain tissues to help determine the causes of Alzheimer's disease and other related disorders.

21 Sep 2022

UEA researchers make important discovery about how prostate cancer may begin

Researchers at the University of East Anglia have made an important discovery about how prostate cancer may start to develop.

21 Sep 2022

Virology of the human monkeypox virus

A new review to be posted in the Virus Research journal aims to provide an overview of the recent advances reported concerning hMPXV virology.

21 Sep 2022

Medulloblastomas originate much earlier in pregnancy than previously thought and may be preventable

An aggressive type of pediatric brain tumor, medulloblastoma, exists in a pre-malignant form at birth after initially developing during the first or second trimester of pregnancy, according to a new international study.

21 Sep 2022

Scientists track origins of group 3 and group 4 medulloblastoma to the rhombic lip

Scientists at St. Jude Children's Research Hospital have discovered which cells give rise to certain high-risk groups of medulloblastoma.

21 Sep 2022

New genetic discovery improves understanding of congenital heart disease

A new study led by the Masonic Medical Research Institute published in the journal Cells shows for the first time that a particular gene, called VGLL4, is required for embryo development but is dispensable for myocardial growth.

21 Sep 2022

Synthetic mucin gels against HIV-1 and HSV-2 transmission

In a new study, researchers assessed the effectiveness of synthetic mucin gels in the inhibition of human immunodeficiency virus-1 (HIV-1) and herpes simplex virus-2 (HSV-2) Transmission.

21 Sep 2022

Researchers devise rules for a faster, more effective way to identify tuberculosis treatments

Imagine you have 20 new compounds that have shown some effectiveness in treating a disease like tuberculosis (TB), which affects 10 million people worldwide and kills 1.5 million each year.

21 Sep 2022

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer's disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, according to a new USC study.

21 Sep 2022

Public-private collaboration receives grant for research on microbiota-boosted cancer therapy

Health~Holland has awarded close to € 800,000 to a public-private partnership between UMC Utrecht, Artizan Biosciences, Inc. (USA) and MicroViable Therapeutics (Spain) to unravel how the intestinal microbiota can be exploited to boost cancer immunotherapy and limit therapy side-effects.

21 Sep 2022

Cell News and Research

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

New board members bring significant leadership experience in the biotech sector

Scientists uncover key details of an immune-cell process that underlies excessive inflammation

New modeling system identifies potential therapeutics for autosomal recessive polycystic kidney disease

Deep mutational scanning for SARS-CoV-2 Omicron BA.1 and BA.2 subvariants

All SARS-CoV-2 variants blocked by a simple peptide with nanomolar neutralizing efficacy

Mount Sinai researchers use unbiased AI-based method to study the causes of cognitive impairment

UEA researchers make important discovery about how prostate cancer may begin

Virology of the human monkeypox virus

Medulloblastomas originate much earlier in pregnancy than previously thought and may be preventable

Scientists track origins of group 3 and group 4 medulloblastoma to the rhombic lip

New genetic discovery improves understanding of congenital heart disease

Synthetic mucin gels against HIV-1 and HSV-2 transmission

Researchers devise rules for a faster, more effective way to identify tuberculosis treatments

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

Public-private collaboration receives grant for research on microbiota-boosted cancer therapy

What is the efficacy of bioelectronic masks for the detection of respiratory infectious diseases like COVID-19?

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Common genetic variants of APOE associated with COVID mortality

Researchers report development of a self-assembled trimeric RBD subunit vaccine able to prevent SARS-CoV-2 infection

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