Genes News and Research

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Researchers report discovery of new gene linked to Tau accumulation in AD

Tau pathology is one of the defining features of Alzheimer disease (AD), which is the most common form of dementia in older age.

25 Mar 2017

Multipronged study of schizophrenia-associated syndrome receives $3.1 million NIH grant

A research team at Emory University is embarking on a multipronged study of 3q29 deletion syndrome, a genetic mutation associated with a 40-fold increased risk for schizophrenia and a range of other neuropsychiatric conditions including mild to moderate intellectual disability, autism and anxiety.

24 Mar 2017

Researchers pinpoint Jumonji protein as key to Ewing's Sarcoma spread

By the time Ewing's Sarcoma is diagnosed, primarily in teens and young adults, it has often spread from its primary site to other parts of the body, making it difficult to treat.

24 Mar 2017

New gene linked to Tau pathology

Investigators at Rush University Medical Center and the Brigham and Women's Hospital in Boston reported the discovery of a new gene that is associated with susceptibility to a common form of brain pathology called Tau that accumulates in several different conditions, including Alzheimer's disease, certain forms of dementia and Parkinsonian syndromes as well as chronic traumatic encephalopathy that occurs with repeated head injuries.

24 Mar 2017

Scientists discover potential role for 'jumping genes' in ALS

By inserting an amyotrophic lateral sclerosis (ALS)-linked human gene called TDP-43 into fruit flies, researchers at Stony Brook University and Cold Spring Harbor Laboratory discovered a potential role for 'transposons' in the disease.

24 Mar 2017

Parasite's biological clock could help improve treatments for deadly sleeping sickness

The parasite that causes deadly sleeping sickness has its own biological clock that makes it more vulnerable to medications during the afternoon, according to international research that may help improve treatments for one of Africa's most lethal diseases.

24 Mar 2017

Researchers show shared genetic origin between ALS/MND and schizophrenia

Researchers have shown for the first time that Amyotrophic Lateral Sclerosis (ALS), also known as Motor Neurone Disease (MND) and schizophrenia have a shared genetic origin, indicating that the causes of these diverse conditions are biologically linked.

24 Mar 2017

Study reveals intriguing crosstalk between metabolism and epigenetics in cancer development

A study published in Briefings in Functional Genomics investigated how epigenetics can modulate human's genetic program -- it can emphasize or silence genes.

24 Mar 2017

MSK scientists discover epigenetic mechanism promoting breast cancer

Researchers from Memorial Sloan Kettering Cancer Center (MSK) have identified, for the first time, an epigenetic mechanism promoting breast cancer.

24 Mar 2017

Random DNA copying ‘mistakes’ account for most cancer mutations, study finds

Johns Hopkins Kimmel Cancer Center scientists report data from a new study providing evidence that random, unpredictable DNA copying "mistakes" account for nearly two-thirds of the mutations that cause cancer.

24 Mar 2017

Research suggests novel strategy to target genetic anomaly in prostate cancers

New research suggests a novel strategy to target a genetic anomaly that occurs in half of all prostate cancers.

24 Mar 2017

SLU researchers aim to tackle diabetes and obesity by capturing benefits of exercise in pill form

With a series of new grants, Saint Louis University researchers will tackle the twin epidemics of diabetes and obesity by tapping into the potential of two nuclear receptors that control muscle metabolism.

24 Mar 2017

OTUD6B gene mutations linked to physical and intellectual deficits

An international team of researchers from institutions around the world, including Baylor College of Medicine, has discovered that mutations of the OTUD6B gene result in a spectrum of physical and intellectual deficits.

24 Mar 2017

MSU lands $727,000 NIH grant to improve use of fish as disease models for human medicine

Michigan State University has landed a $727,000 grant from the National Institutes of Health to improve the use of fish as disease models for human medicine.

23 Mar 2017

Genome sequencing approach opens door to therapy options for rare, neglected cancers

An international team of scientists led by the Icahn School of Medicine at Mount Sinai and UConn School of Medicine have reported the results of a genome sequencing study for an extremely rare form of cancer.

23 Mar 2017

PSU research shows how viruses can undergo major mutations without losing ability to infect

Portland State University researchers have found that only about half the genes in a specific virus affecting single cell organisms is needed to infect a host. This means the virus can undergo major mutations without losing its ability to survive and infect.

23 Mar 2017

Researchers develop novel genetic score to calculate age-specific risk of Alzheimer's disease

An international team of scientists, led by researchers at University of California San Diego School of Medicine and University of California San Francisco, has developed a novel genetic score that allows individuals to calculate their age-specific risk of developing Alzheimer's disease (AD), based upon genetic information.

22 Mar 2017

New genetic biomarker for colon cancer may lead to development of personalized treatment

Researchers at Baylor Scott & White Research Institute identified a new genetic biomarker for colon cancer that may lead to development of more targeted treatment of the disease.

22 Mar 2017

Penn researcher receives $16.3 million NIAID grant to develop long-sought-after HIV vaccine

Building on earlier work in designing chimeric human-simian immunodeficiency viruses (SHIVs) that serve as a model of HIV infection of humans, George M. Shaw, MD, PhD, a professor of Hematology/Oncology and Microbiology in the Perelman School of Medicine at the University of Pennsylvania, has received $16.3 million over five years from the National Institute of Allergy and Infectious Diseases to develop a long-sought-after HIV vaccine.

22 Mar 2017

Heroin use linked to epigenetic alterations in the brain

Heroin use is associated with excessive histone acetylation, an epigenetic process that regulates gene expression, and more years of drug use correlate with higher levels of hyperacetylation, according to research conducted at The Icahn School of Medicine at Mount Sinai and published in the journal Biological Psychiatry.

22 Mar 2017

Genes News and Research

Researchers report discovery of new gene linked to Tau accumulation in AD

Multipronged study of schizophrenia-associated syndrome receives $3.1 million NIH grant

Researchers pinpoint Jumonji protein as key to Ewing's Sarcoma spread

New gene linked to Tau pathology

Scientists discover potential role for 'jumping genes' in ALS

Parasite's biological clock could help improve treatments for deadly sleeping sickness

Researchers show shared genetic origin between ALS/MND and schizophrenia

Study reveals intriguing crosstalk between metabolism and epigenetics in cancer development

MSK scientists discover epigenetic mechanism promoting breast cancer

Random DNA copying ‘mistakes’ account for most cancer mutations, study finds

Research suggests novel strategy to target genetic anomaly in prostate cancers

SLU researchers aim to tackle diabetes and obesity by capturing benefits of exercise in pill form

OTUD6B gene mutations linked to physical and intellectual deficits

MSU lands $727,000 NIH grant to improve use of fish as disease models for human medicine

Genome sequencing approach opens door to therapy options for rare, neglected cancers

PSU research shows how viruses can undergo major mutations without losing ability to infect

Researchers develop novel genetic score to calculate age-specific risk of Alzheimer's disease

New genetic biomarker for colon cancer may lead to development of personalized treatment

Penn researcher receives $16.3 million NIAID grant to develop long-sought-after HIV vaccine

Heroin use linked to epigenetic alterations in the brain

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