Laboratory News and Research

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Brigham researchers develop automated, low-cost tool to predict a woman's ovulation

Investigators from Brigham and Women's Hospital are developing an automated, low-cost tool to predict a woman's ovulation and aid in family planning.

11 Dec 2018

Specific class of biomarkers can accurately indicate the severity of cancer

A cancer diagnosis tells you that you have cancer, but how that cancer will progress is a terrifying uncertainty for most patients. Researchers at Cold Spring Harbor Laboratory have now identified a specific class of biomarkers that can tell a lot about how aggressive a patient's cancer will be.

11 Dec 2018

Researchers identify immune cell subset that may drive chronic inflammation

For the first time, researchers have identified that an immune cell subset called gamma delta T cells that may be causing and/or perpetuating the systemic inflammation found in normal aging in the general geriatric population and in HIV-infected people who are responding well to drugs (anti-retrovirals).

11 Dec 2018

People who eat red meat have high levels of chemical associated with heart disease, study finds

Researchers have identified another reason to limit red meat consumption: high levels of a gut-generated chemical called trimethylamine N-oxide, that also is linked to heart disease.

11 Dec 2018

New computer model predicts prostate cancer progression

An international team of cancer researchers from Denmark and Germany have used cancer patient data to develop a computer model that can predict the course of disease for prostate cancer.

11 Dec 2018

Research findings could help improve treatment of anxiety and post-traumatic stress disorders

Traumatic experiences can become deeply entrenched in a person's memory. How can fears following a traumatic event be reduced in the long term and prevented from becoming a permanent stress-related disorder? Researchers at the Mainz University Medical Center have recently shed new light on these questions.

11 Dec 2018

Cloned antibodies show potential to treat, diagnose life-threatening fungal infections

Despite public health efforts, many people who get fungal infections in their blood streams die, even if they can be identified and treated with antifungal drugs. These therapies are often ineffective on their own and increasingly the infections are becoming resistant to treatment with some of the front line antifungal drugs.

11 Dec 2018

New method uses water molecules to unlock neurons' secrets

Neurons are brain cells that communicate with each other by sending electrochemical signals along axons. When a neuron is about to release a signal - in the form of an electric charge - it allows ions to pass through its membrane via ion channels.

11 Dec 2018

Researchers develop new system for efficiently producing human norovirus

An Osaka University-led research team has developed a system for simply and efficiently producing human norovirus. By coaxing human induced pluripotent stem cells to develop into a type of cell that usually lines the intestine, they created a cellular environment that can be used for producing the virus, studying how it interacts with human cells, and investigating potential vaccines.

11 Dec 2018

New study reveals yin-yang personality of dopamine

For decades, psychologists have viewed the neurotransmitter dopamine as a double-edged sword: released in the brain as a reward to train us to seek out pleasurable experiences, but also a "drug" the constant pursuit of which leads to addiction.

11 Dec 2018

Researchers capture high-resolution X-ray and NMR image of key immune regulator

A new study by investigators from Brigham and Women's Hospital provides a biophysical and structural assessment of a critical immune regulating protein called human T-cell immunoglobulin and mucin domain containing protein-3 (hTIM-3).

11 Dec 2018

Imagination can help overcome fear and anxiety-related disorders, shows study

Imagine a barking dog, a furry spider or another perceived threat and your brain and body respond much like they would if you experienced the real thing.

11 Dec 2018

Lifespan extension at low temperatures depends on individual's genes, study shows

Why do we age? Despite more than a century of research (and a vast industry of youth-promising products), what causes our cells and organs to deteriorate with age is still unknown.

11 Dec 2018

Researchers aim to identify and target high blood pressure indicators

High blood pressure, or hypertension, is a leading cause of stroke and heart attacks worldwide - and one in four people have it.

10 Dec 2018

Novel personalized medicine tool for assessing inherited colorectal cancer syndrome risk developed

An international team of researchers led by Huntsman Cancer Institute at the University of Utah has developed, calibrated, and validated a novel tool for identifying the genetic changes in Lynch syndrome genes that are likely to be responsible for causing symptoms of the disease.

10 Dec 2018

Scientists find answers to how cancer spreads

How does cancer spread? While studying human brain tumor cells, a team of scientists at the Research Institute of the McGill University Health Centre found some answers to this crucial, yet so far unanswered question.

10 Dec 2018

High-intensity interval exercise could help combat cognitive dysfunction in obese people

It's fast-paced, takes less time to do, and burns a lot of calories. High-intensity interval exercise is widely recognized as the most time-efficient and effective way to exercise.

10 Dec 2018

DDT in Alaskan fish shown to increase risk of cancer

A new study has found that children in Alaska who consume a lot of fish from rivers fed by the Eastern Alaska Mountain Range may be at an increased risk of cancer.

10 Dec 2018

Researchers use new technique to probe hydrogen bonds

Researchers at Carnegie Mellon University have used nuclear resonance vibrational spectroscopy to probe the hydrogen bonds that modulate the chemical reactivity of enzymes, catalysts and biomimetic complexes.

10 Dec 2018

UC San Diego professor receives NCI Outstanding Investigator Award for cancer research

The National Cancer Institute has awarded David Cheresh, PhD, Distinguished Professor and vice chair of Pathology at University of California San Diego School of Medicine, with a $4.2 million Outstanding Investigator Award to continue his research into cancer's ability to overcome stress, gain drug resistance and metastasize.

10 Dec 2018

Laboratory News and Research

Brigham researchers develop automated, low-cost tool to predict a woman's ovulation

Specific class of biomarkers can accurately indicate the severity of cancer

Researchers identify immune cell subset that may drive chronic inflammation

People who eat red meat have high levels of chemical associated with heart disease, study finds

New computer model predicts prostate cancer progression

Research findings could help improve treatment of anxiety and post-traumatic stress disorders

Cloned antibodies show potential to treat, diagnose life-threatening fungal infections

New method uses water molecules to unlock neurons' secrets

Researchers develop new system for efficiently producing human norovirus

New study reveals yin-yang personality of dopamine

Researchers capture high-resolution X-ray and NMR image of key immune regulator

Imagination can help overcome fear and anxiety-related disorders, shows study

Lifespan extension at low temperatures depends on individual's genes, study shows

Researchers aim to identify and target high blood pressure indicators

Novel personalized medicine tool for assessing inherited colorectal cancer syndrome risk developed

Scientists find answers to how cancer spreads

High-intensity interval exercise could help combat cognitive dysfunction in obese people

DDT in Alaskan fish shown to increase risk of cancer

Researchers use new technique to probe hydrogen bonds

UC San Diego professor receives NCI Outstanding Investigator Award for cancer research

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