Genes News and Research

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Researchers uncover gene mutation that may provide answers to unexplained female infertility

Researchers at Baylor College of Medicine, Texas Children's Hospital and Rice University have uncovered a gene mutation that may provide answers to unexplained female infertility. The study appears in Scientific Reports, a member of the Nature family of journals.

22 Mar 2017

Changes in the vascular system could play role in initiating Alzheimer’s disease

As the average age of Americans increases, so too does the problem of Alzheimer's, one of the world's most common neurological diseases. In recent years, scientists have explored many new approaches to clear the plaques and tangles in the brain that characterize the condition, but the new drugs have largely turned out to be disappointing.

22 Mar 2017

Penn researcher wins Scientific Innovations Award from Chicago-based Brain Research Foundation

James Eberwine, PhD, the Elmer Holmes Bobst Professor of Systems Pharmacology and Translational Therapeutics at the Perelman School of Medicine at the University of Pennsylvania, has received the 2017 Scientific Innovations Award from the Chicago-based Brain Research Foundation, which supports research for preventing and treating neurological diseases.

22 Mar 2017

Study identifies potential Achilles heel of kinase-driven cancers

Scientists identify two signaling proteins in cancer cells that make them resistant to chemotherapy, and show that blocking the proteins along with chemotherapy eliminate human leukemia in mouse models.

22 Mar 2017

Research shows how Ohr enzyme plays central role in bacterial anti-oxidant defense

A research project conducted at the University of São Paulo in Brazil in collaboration with other Brazilian research institutions and abroad has revealed new aspects of the action mechanism of organic hydroperoxide resistance (Ohr) enzyme, which enables several species of bacteria to neutralize oxidizing substances released by the defense system of the host organism, be it a plant or an animal.

21 Mar 2017

New study correlates 80 cancer-related gene mutations with 34 AML subgroups

A large, new study of adults with acute myeloid leukemia (AML) correlates 80 cancer-related gene mutations with five subtypes of AML, which are defined by the presence of specific chromosomal abnormalities. The findings might help guide mutation testing and treatment decisions in the future.

21 Mar 2017

Efficacy of innovative gene therapy can be tested quickly and cost-effectively using new cellular model

Using a new cellular model, innovative gene therapy approaches for the hereditary immunodeficiency Chronic Granulomatous Disease can be tested faster and cost-effectively in the lab for their efficacy.

21 Mar 2017

Maternal infections during pregnancy may alter genes key to prenatal brain development

If a mother picks up an infection during pregnancy, her immune system will kick into action to clear the infection - but this self-defence mechanism may also have a small influence how her child's brain develops in the womb, in ways that are similar to how the brain develops in autism spectrum disorders.

21 Mar 2017

Genotype-guided warfarin dosing linked to reduced risk of adverse events

Using genetic testing to help personalize doses of warfarin therapy given to patients undergoing elective orthopedic surgery appears to lower the risk of combined adverse events compared with clinically guided dosing, according to research presented at the American College of Cardiology's 66th Annual Scientific Session.

21 Mar 2017

New gene-silencing drugs cut cholesterol levels by half in early research

The first in a new class of gene-silencing drugs, known as inclisiran, has been shown to halve cholesterol levels in patients at risk of cardiovascular disease.

21 Mar 2017

Duke scientists use mathematical tools to track how microbial evolution unfolded

As the human species evolved over the last six million years, our resident microbes did the same, adapting to vastly different conditions on our skin and in our mouths, noses, genitalia and guts.

21 Mar 2017

Researchers develop new method that uses gene editing to find cancer's weak spots

Genetic mutations that cause cancer also weaken cancer cells, creating an opportunity for researchers to develop drugs that will selectively kill them, while sparing normal cells.

20 Mar 2017

Methylation status of ten positions in genome correlates with all-cause mortality

Various chemical modifications in the genome determine whether genes are read or deactivated. Methyl labels in the DNA play a key role in this "epigenetic" regulation of gene activity.

20 Mar 2017

Researchers discover new genes that help prevent prostate and other cancers

New genes which help prevent prostate, skin and breast cancer development in mice have been discovered by researchers at the Wellcome Trust Sanger Institute and their collaborators.

20 Mar 2017

Circadian misalignments may favor diabetes development

Like almost all light-sensitive living beings, human beings follow biological rhythms set on a period of about 24 hours.

20 Mar 2017

World's first licence for mitochondrial donation IVF may enable women to have disease-free babies

Eminent UK reproductive and genetics experts have become the first in the world licensed to provide a revolutionary IVF procedure using donor DNA – which they spent decades developing – enabling women carrying potentially fatal mitochondrial disease to have healthy, genetically-related babies.

20 Mar 2017

Linking RNA to autoimmune diseases

An interview with Dr. Chase Spurlock, CEO, discussing IQuity's research into IncRNAs and how they are linked to autoimmue diseases.

20 Mar 2017

Research findings point to new strategies for tapping into plant energy to produce biofuels, biomaterials

Even plants have to live on an energy budget. While they're known for converting solar energy into chemical energy in the form of sugars, plants have sophisticated biochemical mechanisms for regulating how they spend that energy. Making oils costs a lot.

17 Mar 2017

Drosophila models help illuminate molecular mechanisms underlying nephrotic syndrome

The majority of genes associated with nephrotic syndrome (NS) in humans also play pivotal roles in Drosophila renal function, a conservation of function across species that validates transgenic flies as ideal pre-clinical models to improve understanding of human disease, a Children's National Health System research team reports in a recent issue of Human Molecular Genetics.

17 Mar 2017

New NuGenius gel imaging system powered by Raspberry Pi computer offers accurate method to detect disease causing genes

Syngene, a world-leading manufacturer of image analysis solutions, is pleased to introduce its powerful, NuGenius gel imaging system, the first in the world to be run by a Raspberry Pi computer.

From Syngene 17 Mar 2017

Genes News and Research

Researchers uncover gene mutation that may provide answers to unexplained female infertility

Changes in the vascular system could play role in initiating Alzheimer’s disease

Penn researcher wins Scientific Innovations Award from Chicago-based Brain Research Foundation

Study identifies potential Achilles heel of kinase-driven cancers

Research shows how Ohr enzyme plays central role in bacterial anti-oxidant defense

New study correlates 80 cancer-related gene mutations with 34 AML subgroups

Efficacy of innovative gene therapy can be tested quickly and cost-effectively using new cellular model

Maternal infections during pregnancy may alter genes key to prenatal brain development

Genotype-guided warfarin dosing linked to reduced risk of adverse events

New gene-silencing drugs cut cholesterol levels by half in early research

Duke scientists use mathematical tools to track how microbial evolution unfolded

Researchers develop new method that uses gene editing to find cancer's weak spots

Methylation status of ten positions in genome correlates with all-cause mortality

Researchers discover new genes that help prevent prostate and other cancers

Circadian misalignments may favor diabetes development

World's first licence for mitochondrial donation IVF may enable women to have disease-free babies

Linking RNA to autoimmune diseases

Research findings point to new strategies for tapping into plant energy to produce biofuels, biomaterials

Drosophila models help illuminate molecular mechanisms underlying nephrotic syndrome

New NuGenius gel imaging system powered by Raspberry Pi computer offers accurate method to detect disease causing genes

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