Genes News and Research

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Scientists identify genetic clues to chronic kidney disease

Using international genomic studies backed by proof-of-concept cell experiments, researchers have identified two genes that contribute to the chronic kidney disease glomerulonephritis.

16 Mar 2017

Young researchers explore impact of prolonged Zika viremia in pregnant women, fetuses and infants

A Maryland woman traveled to the Dominican Republic early in her pregnancy, spending three weeks with family. She felt dizzy and tired and, at first, attributed the lethargy to jet lag.

16 Mar 2017

Dietary anti-cancer compound from broccoli may work by influence on long non-coding RNAs

Researchers have discovered one of the reasons why broccoli may be good for your health.

16 Mar 2017

Innovative strategy uses genetically modified viruses to selectively attack tumor cells

Scientists at the IDIBAPS Biomedical Research Institute and at the Institute for Research in Biomedicine lead a study in which they have designed a new strategy to get genetically modified viruses to selectively attack tumor cells without affecting healthy tissues.

16 Mar 2017

Study provides insights into genetic, neuronal circuit mechanisms linked to autism's impaired sociability

Researchers at Beth Israel Deaconess Medical Center have gained new insight into the genetic and neuronal circuit mechanisms that may contribute to impaired sociability in some forms of Autism Spectrum Disorder.

16 Mar 2017

Researchers unravel protein dosage compensation mechanism in genes

Researchers at Okayama University report in PLOS Genetics which genes from the yeast genome exhibit dosage compensation — the ability to temper protein production when the corresponding encoding gene’s copy number increases.

16 Mar 2017

Study reveals novel mutations in mucosal melanoma that may pave way for new therapies

Not all melanomas are created equal. While most melanomas appear on the skin as the result of sun exposure, a small subset of melanomas arise spontaneously from mucosal tissues.

15 Mar 2017

UB research yields neural crest cells from adult skin cells without genetic modification

A discovery, several years in the making, by a University at Buffalo research team has proven that adult skin cells can be converted into neural crest cells (a type of stem cell) without any genetic modification, and that these stem cells can yield other cells that are present in the spinal cord and the brain.

15 Mar 2017

CUMC researchers discover common genetic variant that impacts brain aging

Columbia University Medical Center researchers have discovered a common genetic variant that greatly impacts normal brain aging, starting at around age 65, and may modify the risk for neurodegenerative diseases.

15 Mar 2017

LJI researchers unravel molecular underpinnings of exhausted T cells

One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells.

15 Mar 2017

Study findings could lead to novel therapies for preventing vision loss from degenerative retinal diseases

Silencing a gene called Nrl in mice prevents the loss of cells from degenerative diseases of the retina, according to a new study.

15 Mar 2017

Researchers suggest potential new way to restore healthy intestinal function in older people

Intestinal stem cells rejuvenate daily so bowels will stay healthy and function normally, but a new study in Cell Reports suggests they also age along with people and lose their regenerative capacity.

15 Mar 2017

Topical curcumin gel improves healing of burns and scalds

What is the effect of Topical Curcumin Gel for treating burns and scalds? In a recent research paper, published in the open access journal BioDiscovery, Dr. Madalene Heng, Clinical Professor of Dermatology at the David Geffen School of Medicine, stresses that use of topical curcumin gel for treating skin problems, like burns and scalds, is very different, and appears to work more effectively, when compared to taking curcumin tablets by mouth for other conditions.

14 Mar 2017

Low levels of allopregnanolone hormone may predict risk of postpartum depression

In a small-scale study of women with previously diagnosed mood disorders, Johns Hopkins researchers report that lower levels of the hormone allopregnanolone in the second trimester of pregnancy were associated with an increased chance of developing postpartum depression in women already known to be at risk for the disorder.

14 Mar 2017

Scientists create first model of anorexia nervosa using iPSCs derived from adolescent females

An international research team, led by scientists at University of California San Diego School of Medicine, has created the first cellular model of anorexia nervosa (AN), reprogramming induced pluripotent stem cells (iPSCs) derived from adolescent females with the eating disorder.

14 Mar 2017

York researchers move closer to finding new treatments for chronic bladder diseases

Using human cells, they have mapped how different proteins bind along the DNA to control which genes are active during barrier formation.

14 Mar 2017

Probiotics could be less effective when taken alongside balanced diet, research suggests

To combat the effects of a poor diet, probiotics may be just the thing. However, surprising new research from UNSW suggests probiotics are much less effective when taken alongside a balanced diet, and could even impair certain aspects of memory.

14 Mar 2017

Heroin use linked to epigenetic alterations in the brain

The past few years have seen an explosion of heroin abuse and deaths from opiate overdose. But little is known about the molecular underpinnings of heroin addiction.

14 Mar 2017

Scientists announce landmark database of lifespan-extending drugs and compounds

Scientists from the Biogerontology Research Foundation (BGRF) and University of Liverpool have announced a landmark database of lifespan-extending drugs and compounds called DrugAge.

14 Mar 2017

Defect in non-coding DNA could give rise to language impairments in children

The human genome is made up of ~3 billion letters of DNA and at each position it is possible to have different letters, called variants. Some variants are harmless but others can be detrimental, making it a mammoth task to find out which variants cause a disorder.

14 Mar 2017

Genes News and Research

Scientists identify genetic clues to chronic kidney disease

Young researchers explore impact of prolonged Zika viremia in pregnant women, fetuses and infants

Dietary anti-cancer compound from broccoli may work by influence on long non-coding RNAs

Innovative strategy uses genetically modified viruses to selectively attack tumor cells

Study provides insights into genetic, neuronal circuit mechanisms linked to autism's impaired sociability

Researchers unravel protein dosage compensation mechanism in genes

Study reveals novel mutations in mucosal melanoma that may pave way for new therapies

UB research yields neural crest cells from adult skin cells without genetic modification

CUMC researchers discover common genetic variant that impacts brain aging

LJI researchers unravel molecular underpinnings of exhausted T cells

Study findings could lead to novel therapies for preventing vision loss from degenerative retinal diseases

Researchers suggest potential new way to restore healthy intestinal function in older people

Topical curcumin gel improves healing of burns and scalds

Low levels of allopregnanolone hormone may predict risk of postpartum depression

Scientists create first model of anorexia nervosa using iPSCs derived from adolescent females

York researchers move closer to finding new treatments for chronic bladder diseases

Probiotics could be less effective when taken alongside balanced diet, research suggests

Heroin use linked to epigenetic alterations in the brain

Scientists announce landmark database of lifespan-extending drugs and compounds

Defect in non-coding DNA could give rise to language impairments in children

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