Genes News and Research

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Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Researchers at Monash University and Peter MacCallum Cancer Centre have identified for the first time how a new class of epigenetic drug engages with the immune system to kill off cancer cells, offering powerful new pathways for enhanced blood cancer therapies.

1 Mar 2017

Immune system defect makes Addison’s patients prone to respiratory infections

Research led by University of Birmingham scientists has found that people suffering from the adrenal disorder known as Addison's disease suffer from an immune system defect which makes them prone to potentially deadly respiratory infections.

1 Mar 2017

Researchers develop improved method for using graphene-based transistors to detect harmful genes

Researchers in India and Japan have developed an improved method for using graphene-based transistors to detect disease-causing genes.

1 Mar 2017

Using Spherical Nucleic Acids to Track and Treat Disease

Spherical nucleic acids are structures that are made by taking a nanoparticle template and using chemistry to arrange short strands of DNA or RNA on the surface of those particles. The spherical core of the nanoparticle creates a spherical arrangement of DNA or RNA, similar to tiny little balls of nucleic acids.

From Pittcon 1 Mar 2017

Two migration proteins increase predictive ability of biomarker for pancreatic cancer

Adding two blood-borne proteins associated with cancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Institute.

1 Mar 2017

Mayo Clinic researchers identify new genetic risk factor for late-onset Alzheimer's in African-Americans

A Mayo Clinic research team has found a new gene mutation that may be a risk factor for late-onset Alzheimer's disease in African-Americans.

28 Feb 2017

Genetic variation may be reason for overreaction of immune system to viruses

Researchers at Cardiff University have discovered that genetic variation is the reason why some immune systems overreact to viruses.

28 Feb 2017

Stem cells strictly abide by innate developmental clocks, study shows

The mystery of what controls the range of developmental clocks in mammals — from 22 months for an elephant to 12 days for an opossum — may lie in the strict time-keeping of pluripotent stem cells for each unique species.

28 Feb 2017

Australian scientists discover genetic clues for degenerative eye disease that leads to blindness

Australian scientists have discovered the first evidence of genes that cause Macular Telangiectasia type 2 (MacTel), a degenerative eye disease which leads to blindness and is currently incurable and untreatable.

28 Feb 2017

Scientists gain new insight into early brain pathology of schizophrenia using adult skin cells

The skin cells of four adults with schizophrenia have provided an unprecedented "window" into how the disease began while they were still in the womb, according to a recent paper in Schizophrenia Research.

27 Feb 2017

Researchers identify genetic variants that may contribute to schizophrenia

New research has identified sections of DNA associated with altered regulation of gene expression underlying schizophrenia.

27 Feb 2017

New research reveals complex role of ‘master gene’ that regulates physical differences between sexes

Physical differences between males and females in species are common, but there remains much to learn about the genetic mechanisms behind these differences.

27 Feb 2017

Study finding suggests new ways in which genetic mutations may cause brain disorders

Many kids say they love their mom and dad equally, but there are times when even the best prefers one parent over the other. The same can be said for how the body's cells treat our DNA instructions. It has long been thought that each copy - one inherited from mom and one from dad - is treated the same. A new study from scientists at the University of Utah School of Medicine shows that it is not uncommon for cells in the brain to preferentially activate one copy over the other.

25 Feb 2017

Scientists unravel mechanism of rare, early phenomenon that can affect human development

The genetic material of an organism encodes the instructions that guide its development. These codes are not written in stone; they can change or mutate any time during the life of the organism.

24 Feb 2017

MGH researchers discover regulators of gene expression programs in medulloblastoma

Massachusetts General Hospital researchers have identified a mechanism that controls the expression of genes regulating the growth of the most aggressive form of medulloblastoma, the most common pediatric brain tumor. In their report published online in Cancer Discovery, the team also identifies potential targets for future treatments.

24 Feb 2017

Pitt study sheds light on shared roots of schizophrenia and rheumatoid arthritis

An in-depth computational analysis of genetic variants implicated in both schizophrenia and rheumatoid arthritis by researchers at the University of Pittsburgh points to eight genes that may explain why susceptibility to one of the disorders could place individuals at lower risk for the other, according to the results of a study published today in the journal npj Schizophrenia.

24 Feb 2017

New humanized model enables better characterization of Alzheimer's pathology

Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures.

24 Feb 2017

Researchers chart pathway of multidrug resistant bacteria living in hospital sink drainpipes

Many recent reports have found multidrug resistant bacteria living in hospital sink drainpipes, putting them in close proximity to vulnerable patients.

24 Feb 2017

Feast and famine diet may restore insulin production in diabetes

A landmark study conducted by the University of Southern California and published this week in the journal Cell provides hope for restoring insulin production in patients with diabetes. The study showed that when food is restored to mice on a very low calorie diet that mimics fasting, new insulin-producing cells develop.

24 Feb 2017

Decoding the Exposome Through Breath Biomarkers

The human exposome is probably best defined as “everything that is not the genome.” This is a bit tongue in cheek, but basically, the exposome is comprised of all of the chemicals in your body from the environment, food, consumer products, their metabolites, the endogenous “housekeeping” chemicals, the cellular wastes from energy production, as well as all of the messenger compounds and life supporting chemicals.

From Pittcon 24 Feb 2017

Genes News and Research

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Immune system defect makes Addison’s patients prone to respiratory infections

Researchers develop improved method for using graphene-based transistors to detect harmful genes

Using Spherical Nucleic Acids to Track and Treat Disease

Two migration proteins increase predictive ability of biomarker for pancreatic cancer

Mayo Clinic researchers identify new genetic risk factor for late-onset Alzheimer's in African-Americans

Genetic variation may be reason for overreaction of immune system to viruses

Stem cells strictly abide by innate developmental clocks, study shows

Australian scientists discover genetic clues for degenerative eye disease that leads to blindness

Scientists gain new insight into early brain pathology of schizophrenia using adult skin cells

Researchers identify genetic variants that may contribute to schizophrenia

New research reveals complex role of ‘master gene’ that regulates physical differences between sexes

Study finding suggests new ways in which genetic mutations may cause brain disorders

Scientists unravel mechanism of rare, early phenomenon that can affect human development

MGH researchers discover regulators of gene expression programs in medulloblastoma

Pitt study sheds light on shared roots of schizophrenia and rheumatoid arthritis

New humanized model enables better characterization of Alzheimer's pathology

Researchers chart pathway of multidrug resistant bacteria living in hospital sink drainpipes

Feast and famine diet may restore insulin production in diabetes

Decoding the Exposome Through Breath Biomarkers

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