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TSRI researchers solve structure of key protein in deadly, but little known virus

What began as a summer internship project designed for an undergraduate student evolved into a one-year study of one of the deadliest, but little known viruses. Researchers at The Scripps Research Institute (TSRI) have now solved the structure of a key protein in the Nipah virus, which could pave the way for the development of a much-needed antiviral drug.

20 Nov 2013

Rapid DNA biochip tests for screening disease-causing bacteria

Patients affected by a bacterial infection can usually be treated with an antibiotic. But sometimes a resistant bacterial strain is causing the infection. In a hospital setting, doctors ideally want to know if they are dealing with such bacteria and which drugs they should choose. But if the doctor runs a test it can take days to get a result. Now, a European project is paving the way for much more rapid tests using DNA biochips. The aim is to rapidly screen disease-causing bacteria using a microarray to spot which resistant genes are present in bacteria.

20 Nov 2013

Call to recognize lung diseases as leading causes of morbidity and mortality

Experts from the world's leading lung organisations have come together for the first time to call for a worldwide effort to improve healthcare policies, systems and care delivery to make a positive difference to the lung health of the world.

20 Nov 2013

NeutroPhase irrigation therapy and NPWT help treat severe flesh eating and wound infections

NovaBay Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company developing topical non-antibiotic antimicrobial products, today announced the publication of a scientific paper by Dr. John R. Crew of Seton Medical Center, Daly City, California, describing the first use of adjunctive NeutroPhase irrigation therapy in conjunction with Negative Pressure Wound Therapy to successfully manage the severely-infected wound in the arm of a patient with life-threatening 'flesh-eating' disease.

20 Nov 2013

Experts call for worldwide effort to make positive difference to the lung health

Experts from the world’s leading lung organisations have come together for the first time to call for a worldwide effort to improve healthcare policies, systems and care delivery to make a positive difference to the lung health of the world.

20 Nov 2013

Simple blood test may predict people at highest risk for developing heart problems

For years, doctors have been divided on how effective annual testing and screenings are for apparently healthy individuals. New research, however, shows that a simple blood test may predict who is at highest risk to develop heart problems - and how long these people may have to live.

20 Nov 2013

UC San Diego study suggests racial inequality leads to higher mortality in cancer patients

Researchers at the University of California, San Diego School of Medicine say metastatic colorectal cancer patients of African-American descent are less likely to be seen by cancer specialists or receive cancer treatments. This difference in treatment explains a large part of the 15 percent higher mortality experienced by African-American patients than non-Hispanic white patients.

20 Nov 2013

Aortic valve replacement improves survival and outcomes in elderly patients

Jose Augusto Barreto-Filho, M.D., Ph.D., of the Federal University of Sergipe and the Clinica e Hospital Sao Lucas, Sergipe, Brazil, and colleagues assessed procedure rates and outcomes of surgical aortic valve replacement (AVR) among 82,755,924 Medicare fee-for-service beneficiaries between 1999 and 2011.

19 Nov 2013

Study reveals substantial economic impact of HAIs following cardiac surgery

After cardiac surgery, healthcare-associated infections (HAIs) are common complications associated with increased morbidity, mortality, and use of resources.

19 Nov 2013

Study finds patients treated with varespladib drug more likely to experience cardiovascular events

Patients with acute coronary syndrome who were treated with the experimental drug varespladib were more likely to experience additional cardiovascular events - including sudden death, heart attack and stroke - than those treated with placebo, according to research from the Cleveland Clinic Coordinating Center for Clinical Research (C5Research).

19 Nov 2013

Long-term use of PDE3 inhibitors can lead to increased risk for sudden cardiac death

Drugs known as PDE3 inhibitors save many lives by helping failing hearts do a better job of pumping blood. But those same medications come with a sometimes deadly cost when taken for long periods: an increased risk for sudden cardiac death.

19 Nov 2013

Annual rates of CPR training vary widely across the U.S.

Annual rates of CPR training in the United States are low and vary widely across the country, but the communities most in need of training are the least likely to be trained, according to a new study from the Duke Clinical Research Institute.

19 Nov 2013

MOH scaling up innovative EONC model to save lives of mothers and newborns

The Ecuadorian Ministry of Health is scaling up an innovative essential obstetric and newborn care model piloted by the USAID-funded EONC Networks Project in Cotopaxi province. The project, which is managed by the Center for Human Services, designed and implemented the model in close alliance with the MOH, USAID, and national and provincial NGOs, providers, and users.

19 Nov 2013

Study examines two surgical approaches for treatment of severe ischemic mitral regurgitation

The Cardiothoracic Surgical Trials Network, whose Data and Clinical Coordinating Center is at Icahn School of Medicine at Mount Sinai, is reporting for the first time evidence on whether or not there is any significant difference between the two current surgical approaches to treat patients with severe ischemic mitral regurgitation -- mitral valve repair and mitral valve replacement.

19 Nov 2013

Research advances in search for biomarkers that may predict lung cancer

The professor of the Faculty of Medicine and Dentistry of the University of Valencia Carlos Camps has participated in a research that advances in the search for biomarkers that may predict lung cancer.

19 Nov 2013

Medical–surgical integration ‘boosts neoadjuvant chemotherapy use for bladder cancer’

Research from the USA indicates that a multidisciplinary approach and coordination between medical and surgical oncology services can help optimize the use of neoadjuvant chemotherapy for bladder cancer.

18 Nov 2013

Researchers solve structure of key protein in Nipah virus

What began as a summer internship project designed for an undergraduate student evolved into a one-year study of one of the deadliest, but little known viruses.

18 Nov 2013

Kiadis reports successful Phase II enrollment for CR-AIR-007 ATIR blood cancer treatment study

Kiadis Pharma B.V., a clinical stage biopharmaceutical company developing treatments for blood cancers, today announces the successful Phase II enrollment of approximately ten patients of whom the majority have already been transplanted and received ATIR™. Kiadis Pharma's lead program, ATIR™, is a cell-based product designed to enable stem cell transplantations from partially mismatched (haploidentical) family donors for blood cancer patients who do not have a standard of care stem cell donor available. Topline data from the trial (CR-AIR-007) is expected in the first half of 2014.

18 Nov 2013

Experts develop new working formulation for reporting of cardiac antibody-mediated rejection

Antibody-mediated rejection of the transplanted heart is a recognized clinical complication and a major limitation to survival of patients who have undergone heart transplantation. Experts have now developed a new working formulation for the pathologic diagnosis, grading, and reporting of cardiac antibody-mediated rejection.

18 Nov 2013

$23.8M NIH grant supports multi-center, multidisciplinary study on deadly bleeding syndrome

A new five-year, $23.8 million National Institutes of Health (NIH) grant will support a multi-center, multidisciplinary study on a deadly bleeding syndrome - called coagulopathy - that occurs without warning in some trauma patients.

16 Nov 2013

Mortality News and Research

TSRI researchers solve structure of key protein in deadly, but little known virus

Rapid DNA biochip tests for screening disease-causing bacteria

Call to recognize lung diseases as leading causes of morbidity and mortality

NeutroPhase irrigation therapy and NPWT help treat severe flesh eating and wound infections

Experts call for worldwide effort to make positive difference to the lung health

Simple blood test may predict people at highest risk for developing heart problems

UC San Diego study suggests racial inequality leads to higher mortality in cancer patients

Aortic valve replacement improves survival and outcomes in elderly patients

Study reveals substantial economic impact of HAIs following cardiac surgery

Study finds patients treated with varespladib drug more likely to experience cardiovascular events

Long-term use of PDE3 inhibitors can lead to increased risk for sudden cardiac death

Annual rates of CPR training vary widely across the U.S.

MOH scaling up innovative EONC model to save lives of mothers and newborns

Study examines two surgical approaches for treatment of severe ischemic mitral regurgitation

Research advances in search for biomarkers that may predict lung cancer

Medical–surgical integration ‘boosts neoadjuvant chemotherapy use for bladder cancer’

Researchers solve structure of key protein in Nipah virus

Kiadis reports successful Phase II enrollment for CR-AIR-007 ATIR blood cancer treatment study

Experts develop new working formulation for reporting of cardiac antibody-mediated rejection

$23.8M NIH grant supports multi-center, multidisciplinary study on deadly bleeding syndrome

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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