Genes News and Research

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World's largest GWAS on proteomics uncovers molecular mechanisms of complex diseases

The Helmholtz Zentrum München has published results of the largest genome-wide association study on proteomics to date.

16 Feb 2017

Doctors use targeted molecular drugs to treat fatal cancerous blood syndromes

Genomic testing of biopsies from patients with deadly, treatment-resistant cancerous blood syndromes called histiocytoses allowed doctors to identify genes fueling the ailments and use targeted molecular drugs to successfully treat them.

16 Feb 2017

HMS scientists listen to crosstalk between gut microbes and immune system

The human gut is home to some 100 trillion bacteria, comprising between 250 and 500 species. This astounding array of organisms, collectively known as the gut microbiome, is a powerful regulator of disease and health and has been implicated in conditions ranging from inflammatory bowel disease to multiple sclerosis.

16 Feb 2017

IBS scientists modify fat content in soybean oil using new CRISPR-Cpf1 technology

A team from the Center for Genome Engineering, within the Institute for Basic Research (IBS), succeeded in editing two genes that contribute to the fat contents of soybean oil using the new CRISPR-Cpf1 technology: an alternative of the more widely used gene editing tool CRISPR-Cas9. The results of this new plant gene editing method, applied to soybeans and wild tobacco genes, are published in Nature Communications.

16 Feb 2017

UNIGE researchers develop new technique to improve diagnosis of genetic diseases

When a child is conceived, he or she receives DNA from both parents. The child's own genome thus consists of a maternal and a paternal genome. However, some genes — about 100 out of the 20,000 encoded genes— are exclusively expressed either from the maternal or from the paternal genome, with the other copy of the gene remaining silent.

16 Feb 2017

Gene therapy treats myotubular myopathy in dogs

The rare disorder, called myotubular myopathy, or MTM, affects only males. It causes fatal muscle wasting. Both dogs and boys with the disease typically succumb in early life due to breathing difficulties.

16 Feb 2017

Yale researchers find potential new way to combat brain cancer

A recent Yale study may have found a new way to fight brain cancer.

15 Feb 2017

Signals from fat cells may aid in diagnostics for metabolic conditions

Fat cells are not simply big blobs of lipid quietly standingby in the body--instead, they send out hormones and other signaling proteins that affect many types of tissues.

15 Feb 2017

HCI researchers uncover how epithelial cells naturally turn over to maintain constant numbers

Research published today in Nature from scientists at Huntsman Cancer Institute (HCI) at the University of Utah shows how epithelial cells naturally turn over, maintaining constant numbers between cell division and cell death.

15 Feb 2017

Scientists develop new bioinformatics tool to make biological experiments more transparent

Biological experiments are generating increasingly large and complex sets of data. This has made it difficult to reproduce experiments at other research laboratories in order to confirm - or refute - the results.

15 Feb 2017

Researchers discover sulfide-responsive protein that regulates photosynthesis in purple bacteria

Recent evidence demonstrates that the origins of photosynthesis can be found in deep sea hydrothermal vents, where microbes evolved to obtain energy from ejected hydrogen sulfide and methane gases.

15 Feb 2017

Analyzing copies of genes may offer new therapeutic approaches for ovarian cancer

A team of 18 University of California San Diego School of Medicine and Moores Cancer Center researchers has developed a new tool to analyze an often overlooked aspect of cancer genetics -- an alteration that results in the loss or gain in a copy of a gene.

15 Feb 2017

SBP scientists identify autophagy linked to beneficial effects of enduring temporary stress

Biologists have known for decades that enduring a short period of mild stress makes simple organisms and human cells better able to survive additional stress later in life.

15 Feb 2017

Scientists identify genetic signature of risk for type 2 diabetes

Why do some people get Type 2 diabetes, while others who live the same lifestyle never do? For decades, scientists have tried to solve this mystery - and have found more than 80 tiny DNA differences that seem to raise the risk of the disease in some people, or protect others from the damagingly high levels of blood sugar that are its hallmark.

14 Feb 2017

Study provides new insight into causes of rare metabolic disorder

Just before Rare Disease Day 2017, a study from the Monell Center and collaborating institutions provides new insight into the causes of trimethylaminura, a genetically-transmitted metabolic disorder that leads to accumulation of a chemical that smells like rotting fish.

14 Feb 2017

Emory researchers reveal 'matchmaker' role for protein linked to SMA

A puzzling question has lurked behind SMA, the leading genetic cause of death in infants. The disorder leads to reduced levels of the SMN protein, which is thought to be involved in processing RNA, something that occurs in every cell in the body.

14 Feb 2017

Salk professor receives inaugural Sjöberg Prize for groundbreaking cancer research

Salk Professor Tony Hunter, who holds an American Cancer Society Professorship, has been awarded $500,000 as part of the $1 million Royal Swedish Academy of Sciences' inaugural Sjöberg Prize for Cancer Research for "groundbreaking studies of cellular processes that have led to the development of new and effective cancer drugs."

14 Feb 2017

Genetic proneness to illnesses may contribute to self-reported tiredness and low energy

Already feeling drained so early in the year? Genes might contribute in a small but significant way to whether people report being tired and low in energy.

14 Feb 2017

Children born of fathers exposed to nicotine inherit enhanced chemical tolerance, study shows

A father's nicotine use may have a significant impact on children's risk of some diseases. In a study published in the online biomedical sciences journal eLife, Oliver J. Rando, MD, PhD, and colleagues at UMass Medical School, demonstrate that mice born of fathers who are habitually exposed to nicotine inherit enhanced chemical tolerance and drug clearance abilities.

14 Feb 2017

Researchers decode how ingenious tick immune system fights myriad of microbes

Everyone agrees that ticks are exceedingly nasty creatures. For hundreds of millions of years, they have survived on Earth by sucking blood from their victims for days, often leaving behind terrible diseases as a thank-you note.

14 Feb 2017

Genes News and Research

World's largest GWAS on proteomics uncovers molecular mechanisms of complex diseases

Doctors use targeted molecular drugs to treat fatal cancerous blood syndromes

HMS scientists listen to crosstalk between gut microbes and immune system

IBS scientists modify fat content in soybean oil using new CRISPR-Cpf1 technology

UNIGE researchers develop new technique to improve diagnosis of genetic diseases

Gene therapy treats myotubular myopathy in dogs

Yale researchers find potential new way to combat brain cancer

Signals from fat cells may aid in diagnostics for metabolic conditions

HCI researchers uncover how epithelial cells naturally turn over to maintain constant numbers

Scientists develop new bioinformatics tool to make biological experiments more transparent

Researchers discover sulfide-responsive protein that regulates photosynthesis in purple bacteria

Analyzing copies of genes may offer new therapeutic approaches for ovarian cancer

SBP scientists identify autophagy linked to beneficial effects of enduring temporary stress

Scientists identify genetic signature of risk for type 2 diabetes

Study provides new insight into causes of rare metabolic disorder

Emory researchers reveal 'matchmaker' role for protein linked to SMA

Salk professor receives inaugural Sjöberg Prize for groundbreaking cancer research

Genetic proneness to illnesses may contribute to self-reported tiredness and low energy

Children born of fathers exposed to nicotine inherit enhanced chemical tolerance, study shows

Researchers decode how ingenious tick immune system fights myriad of microbes

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