Brain Cell News and Research

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Discovery of mechanism that may explain Parkinson's and other neurological disorders

Studying just eight families worldwide, the international team of researchers have discovered a genetic defect that results in profound depression and parkinsonism in a disorder known as Perry syndrome.

12 Jan 2009

Six more obesity genes identified

The international GIANT (Genetic Investigation of Anthropometric Parameters) consortium works on the discovery of obesity genes.

8 Jan 2009

Growth of new brain cells requires 'epigenetic' switch

New cells are born every day in the brain's hippocampus, but what controls this birth has remained a mystery.

8 Jan 2009

New hope for leptin as a solution to obesity

The discovery more than a decade ago of leptin, an appetite-suppressing hormone secreted by fat tissue, generated headlines and great hopes for an effective treatment for obesity.

6 Jan 2009

Collagen VI protects brain cells against amyloid-beta proteins

Scientists from the Gladstone Institute of Neurological Disease (GIND), UCSF, and Stanford have discovered that a certain type of collagen, collagen VI, protects brain cells against amyloid-beta proteins, which are widely thought to cause Alzheimer's disease (AD).

5 Jan 2009

A novel glioblastoma mouse model developed

Researchers at the Salk Institute for Biological Studies have developed a versatile mouse model of glioblastoma-the most common and deadly brain cancer in humans-that closely resembles the development and progression of human brain tumors that arise naturally.

5 Jan 2009

Discovery of potential important pathway for controlling cell loss and survival in Parkinson's disease

Neurologists have observed for decades that Lewy bodies, clumps of aggregated proteins inside cells, appear in the brains of patients with Parkinson's disease and other neurodegenerative diseases.

1 Jan 2009

Moderate drinking lowers risk of Alzheimer's and cognitive decline

Moderate drinkers often have lower risks of Alzheimer's disease and other cognitive loss, according to researchers who reviewed 44 studies.

30 Dec 2008

Matrix fragments trigger fatal excitement

Shredded extracellular matrix (ECM) is toxic to neurons. Chen et al. reveal a new mechanism for how ECM demolition causes brain damage. The study will appear in the December 29, 2008 issue of The Journal of Cell Biology (www.jcb.org).

30 Dec 2008

Scientists reverse brain birth defects using stem cell therapy

Scientists at the Hebrew University of Jerusalem have succeeded in reversing brain birth defects in animal models, using stem cells to replace defective brain cells.

29 Dec 2008

Cardiovascular system proteins play a role in Alzheimer's

Researchers have found that two proteins which work in tandem in the brain's blood vessels present a double whammy in Alzheimer's disease.

22 Dec 2008

Alcohol consumption during pregnancy damages offspring's white matter - brain's connective network

One part of the prenatal brain that may be particularly sensitive to alcohol's effects is white matter, nerve fibers through which information is exchanged between different areas of the central nervous system.

22 Dec 2008

New method offers direct access to the brain through the nose to treat stroke

UT Health Science Center San Antonio researchers, working in a mouse model of stroke, are delivering neuroprotective drugs to the brain by spraying them onto the lining of a nerve in the nose.

18 Dec 2008

Carbon monoxide used to protect mouse nerve cells from damage

Researchers at Johns Hopkins have shown that brain damage was reduced by as much as 62.2 percent in mice who inhale low amounts of carbon monoxide after an induced stroke.

15 Dec 2008

Cellular 'brakes' may slow memory process in aging brains

University of Florida researchers may have discovered why some brain cells necessary for healthy memory can survive old age or disease, while similar cells hardly a hairsbreadth away die.

10 Dec 2008

Hemichannels - new target to treat epileptic seizures following brain trauma or stroke

New therapies for some forms of epilepsy may soon be possible, thanks to a discovery made by a team of University of British Columbia and Vancouver Coastal Health Research Institute neuroscience researchers.

8 Dec 2008

Brain's circuitry survives longer than previously thought in Alzheimer's

Researchers at the Babraham Institute near Cambridge, supported by the Alzheimer's Research Trust and the Biotechnology and Biological Sciences Research Council (BBSRC), have discovered that the brain's circuitry survives longer than previously thought in diseases of ageing such as Alzheimer's disease.

8 Dec 2008