Chimeric Antigen Receptor News and Research

RSS

Texas researcher receives U.S. patent for new class of compounds that protect against TBI

A researcher in the School of Medicine at The University of Texas Health Science Center at San Antonio received a U.S. patent Dec. 31 for his discovery that a class of compounds is protective against traumatic brain injury.

13 Jan 2014

Lifestyle changes and screening tools prove to reduce cancer risk, says doctor

President Nixon funded research to wage a war on cancer, a long battle that we're still fighting today. While the last 40 years haven't brought us a cure, we have made some meaningful progress in developing tools and knowledge to take a bite out of our cancer risk.

10 Jan 2014

Neurovance announces interim results from phase 2a pilot study of EB-1020 SR in patients with all subtypes of ADHD

Neurovance Inc. today announced interim results from its phase 2a pilot study of EB-1020 SR in adult patients with all subtypes of ADHD. With the four week trial fully enrolled and dosing completed in the majority of patients, the results indicate a statistically significant improvement in ADHD symptoms.

10 Jan 2014

Quick tips to avoid carbon monoxide poisoning

Temperatures in the next few days are predicted to be the coldest of the winter so far, and people using space heaters to get some extra warmth into their living and working spaces need to be aware of a potential "silent killer" inside their homes and offices — carbon monoxide (CO).

8 Jan 2014

Research opens door to new direction of PAH treatment

The development of new, more effective vasodilators to treat pulmonary arterial hypertension has been hampered because of their systemic toxicity and adverse side effects. An international team of investigators seeking to surmount these problems and increase drug efficacy have determined that a vascular homing peptide can selectively target hypertensive pulmonary arteries to boost the pulmonary but not systemic effects of vasodilators. Importantly for potential clinical use, this peptide retains its activity when given sublingually. The results using a rat model of PAH are published in the American Journal of Pathology.

8 Jan 2014

State roundup: 'Hope' for Texas' mental health system; rural farmers staying out of health exchanges; Oregon's medical error law

A selection of health policy news from Oregon, Texas, Maryland, California, Georgia and Wisconsin.

3 Jan 2014

First Edition: Jan. 2, 2014

The early morning highlights from the major news organizations, including reports about what to expect of the health law in 2014.

2 Jan 2014

Cell phones, other distractions pose greater threat to teen drivers

Teens may begin their driving habits with great caution, but as months behind the wheel pass, they begin to multi-task at higher frequency rates - dialing cell phones, eating, and talking to passengers, etc. - and therefore greatly raise their risk of crashes and/or near-crash incidents.

2 Jan 2014

Engineered immune cells show antitumor activity in two patients with advanced cancers

Engineered immune cells, called CARTmeso cells, designed to direct antitumor immune responses toward tumors that carry a protein called mesothelin, showed antitumor activity in two patients with advanced cancers that had not responded to prior treatments, according to a study published in Cancer Immunology Research, a journal of the American Association for Cancer Research.

22 Dec 2013

Taking simple steps to stay healthy while traveling can make holidays more enjoyable, says expert

Traveling long distances during the holidays -- whether by car, plane or train -- is a common custom for many Americans, but taking health precautions for the journey isn't often at the top of to-do lists. Taking some simple steps to stay healthy while traveling can make the holidays more enjoyable and safe, according to a Mayo Clinic expert.

17 Dec 2013

Researchers discover that unresponsive patients' brains may recognize photographs of their family, friends

Patients in a vegetative state are awake, breathe on their own, and seem to go in and out of sleep. But they do not respond to what is happening around them and exhibit no signs of conscious awareness. With communication impossible, friends and family are left wondering if the patients even know they are there.

17 Dec 2013

Prescription drug misuse and driving after using drugs on the rise among Ontario students

Alcohol consumption and smoking among Ontario students in grades 7-12 is at an all-time low; however recreational use of over-the-counter drugs is on the rise. Prescription drug misuse and driving after using drugs also remain elevated according to the 2013 Ontario Student Drug Use and Health Survey released by the Centre for Addiction and Mental Health.

16 Dec 2013

Arden Photonics BQM-50 Beam Propagation Analyser Compact offers easier way of characterizing laser beams

The Arden Photonics BQM-50 Beam Propagation Analyser Compact, based on a prototype developed by the National Physical Laboratory, offers customers a quicker and easier way of characterising laser beams to optimise their performance.

13 Dec 2013

Researchers develop first test to identify acute mountain sickness

The first test to identify acute mountain sickness has been developed by a team of researchers in Italy and France and is presented today at EuroEcho-Imaging 2013. The test could revolutionise trekking and climbing by predicting who will develop the potentially deadly condition so they can avoid high altitudes, ascend more gradually or take preventative medication.

12 Dec 2013

New reports demonstrate the effectiveness of modified T cells in treating blood-borne cancers

At the 2013 American Society of Hematology meeting in Dec. 2013, James Kochenderfer, M.D., investigator in the Experimental Transplantation and Immunology Branch, NCI, presented findings from two clinical trials evaluating the use of genetically modified immune system T cells as cancer therapy.

12 Dec 2013

Research shows that person's skull is insufficient to make positive ID of human remains

Forensic experts have long used the shape of a person's skull to make positive identifications of human remains.

12 Dec 2013

CAR therapy shows potential for advancing treatment of patients with ALL and CLL

Novartis is highlighting new research from members of the faculty at the University of Pennsylvania’s Perelman School of Medicine on the investigational chimeric antigen receptor therapy, CTL019. Several studies being presented at the American Society of Hematology annual meeting add to the scientific understanding of CTL019 in the treatment of acute lymphoblastic leukemia and chronic lymphocytic leukemia and build on earlier research findings.

9 Dec 2013

Children and adults with high-risk ALL benefit from novel, personalized cell therapy

Nearly 90 percent of children and adults with a highly aggressive form of acute lymphoblastic leukemia showed no evidence of cancer after receiving a novel, personalized cell therapy that reprograms a patient's immune system. In pilot studies of bioengineered T cells that attack leukemia, 24 of 27 patients (89%) experienced complete responses within 28 days after treatment. In all, 27 patients received the treatment--22 children treated at The Children's Hospital of Philadelphia and five adults treated at the Hospital of the University of Pennsylvania.

9 Dec 2013

Genetically engineered cell therapies demonstrate early efficacy, safety in patients with blood disorders

A series of advancements in genetically engineered cell therapies demonstrate early efficacy and safety in patients with blood disorders for whom standard treatments have been unsuccessful, according to data showcased today during the 55th American Society of Hematology (ASH) Annual Meeting and Exposition in New Orleans.

9 Dec 2013

Novartis to present updates on broad cancer portfolio at ASH and SABCS symposiums

Novartis will present updates on its broad cancer portfolio with more than 240 abstracts at the upcoming American Society of Hematology (ASH) annual meeting and CTRC-AACR San Antonio Breast Cancer Symposium (SABCS).

4 Dec 2013

Chimeric Antigen Receptor News and Research

Texas researcher receives U.S. patent for new class of compounds that protect against TBI

Lifestyle changes and screening tools prove to reduce cancer risk, says doctor

Neurovance announces interim results from phase 2a pilot study of EB-1020 SR in patients with all subtypes of ADHD

Quick tips to avoid carbon monoxide poisoning

Research opens door to new direction of PAH treatment

State roundup: 'Hope' for Texas' mental health system; rural farmers staying out of health exchanges; Oregon's medical error law

First Edition: Jan. 2, 2014

Cell phones, other distractions pose greater threat to teen drivers

Engineered immune cells show antitumor activity in two patients with advanced cancers

Taking simple steps to stay healthy while traveling can make holidays more enjoyable, says expert

Researchers discover that unresponsive patients' brains may recognize photographs of their family, friends

Prescription drug misuse and driving after using drugs on the rise among Ontario students

Arden Photonics BQM-50 Beam Propagation Analyser Compact offers easier way of characterizing laser beams

Researchers develop first test to identify acute mountain sickness

New reports demonstrate the effectiveness of modified T cells in treating blood-borne cancers

Research shows that person's skull is insufficient to make positive ID of human remains

CAR therapy shows potential for advancing treatment of patients with ALL and CLL

Children and adults with high-risk ALL benefit from novel, personalized cell therapy

Genetically engineered cell therapies demonstrate early efficacy, safety in patients with blood disorders

Novartis to present updates on broad cancer portfolio at ASH and SABCS symposiums

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®