Embryo News and Research

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New insights into process of eye-size control in zebrafish

A Purdue University student's research project related to zebrafish eye development could lead to a better understanding of vision problems that affect billions of people worldwide.

3 Aug 2012

Researchers identify how telomerase is recruited to chromosome ends

Stem cells are special. Nestled in muscle and skin, organ and bone, they bide their time over years or decades until called to replace damaged or lost tissue. One secret to their longevity is an enzyme called telomerase, which stills the relentless ticking of the molecular clock that limits the life span of other cells.

3 Aug 2012

Researchers discover surprising and unexpected plasticity in the embryonic endothelium

UCLA stem cell researchers have found for the first time a surprising and unexpected plasticity in the embryonic endothelium, the place where blood stem cells are made in early development.

3 Aug 2012

New research indicates molecular signaling from end to end in peripheral nerve cells

When the longest cells in the body are injured at their farthest reaches, coordinating the cells' repair is no easy task. This is in part because these peripheral nerve cells can be extremely long - up to one meter in adult humans - which is a lot of distance for a molecular distress signal to cover in order to reach the "command center" of the cell's nucleus.

30 Jul 2012

Study validates importin beta1 protein's crucial role in nerve repair

Several years ago, Prof. Michael Fainzilber and his group in the Biological Chemistry Department made a surprising discovery: Proteins thought to exist only near the cell nucleus could also be found in the far-off regions of the body's longest cells - peripheral nerve cells that extend processes called axons, reaching up to a meter in length in adult humans.

27 Jul 2012

Researchers decipher function of β-catenin in generating blood tissue stem cells

Researchers from IMIM (Hospital del Mar Medical Research Institute) have deciphered the function executed by a protein called β-catenin in generating blood tissue stem cells.

26 Jul 2012

Test for motile sperm improves ICSI outcomes

Researchers have developed a new sperm test that could improve pregnancy rates among women treated with intracytoplasmic sperm injection.

23 Jul 2012

Many patients may benefit from day 5 embryo biopsy

Over the last several years Carolina Conceptions has been offering embryo biopsy to rule out chromosomal abnormalities and genetic diseases in future pregnancies. One of the downsides of the technique was that biopsies were performed after 3 days of embryo culture, which was later discovered to limit the ability of the embryo to undergo normal development. This actually reduced the chance of pregnancy, often erasing any advantage that was provided by the biopsy procedure.

21 Jul 2012

FDA grants accelerated approval for Kyprolis to treat multiple myeloma

Ligand Pharmaceuticals Incorporated today announced that its licensee, Onyx Pharmaceuticals, received accelerated approval from the U.S. Food and Drug Administration (FDA) for Kyprolis (carfilzomib) for Injection, a proteasome inhibitor indicated for the treatment of patients with multiple myeloma who have received at least two prior therapies, including bortezomib and an immunomodulatory agent, and have demonstrated disease progression on or within 60 days of completion of the last therapy.

21 Jul 2012

FDA grants accelerated approval to Onyx's Kyprolis for treatment of multiple myeloma

Onyx Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted accelerated approval of Kyprolis (carfilzomib) for Injection, a proteasome inhibitor, indicated for the treatment of patients with multiple myeloma who have received at least two prior therapies, including bortezomib and an immunomodulatory agent, and have demonstrated disease progression on or within 60 days of completion of the last therapy.

21 Jul 2012

Ajuba protein plays a central role in regulating function of heart stem cells

It is not unusual for babies to be born with congenital heart defects. This is because the development of the heart in the embryo is a process which is not only extremely complex, but also error-prone. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now identified a key molecule that plays a central role in regulating the function of stem cells in the heart.

14 Jul 2012

Federal judge to decide Wednesday on Miss. abortion law that could close last clinic

The Republican-appointed judge is expected to rule this week whether to block a law that could effectively shutter the state's only abortion clinic. Abortion politics could also affect the availability of services in Indiana and D.C.

10 Jul 2012

Lipid ceramide helps cells keep cilium or antenna from retracting

A lipid that helps lotion soften the skin also helps cells find and stay in the right location in the body by ensuring they keep their "antennae" up, scientists report.

10 Jul 2012

Single dose breast cancer treatment helps forego 6-7 week radiation regimen

NewYork-Presbyterian Hospital/Weill Cornell Medical Center is the first and only hospital in the five boroughs of New York City to offer women with early stage breast cancer INTRABEAM radiotherapy, an innovative radiation treatment delivered in a single dose at the time of surgery.

5 Jul 2012

Vitrolife's EmbryoGlue medium increases implantation and pregnancy rates

In a study presented at the on-going ESHRE conference in Istanbul, Vitrolife's patent protected medium EmbryoGlue has once again been proven to increase both implantation and pregnancy rates, regardless of hormone stimulation of the endometrium or not.

4 Jul 2012

Italy's first successful pregnancy and delivery following transplantation of ovarian tissue

Although the first successful preservation of fertility from the freezing, thawing and grafting of ovarian tissue was reported eight years ago, the technique has remained experimental and confined to a few specialist centres. Now, with the announcement of a first pregnancy (and subsequent live birth) in Italy following the transplantation of ovarian tissue, there are indications that fertility preservation is moving into the mainstream of reproductive medicine and into a greater number of centres.

4 Jul 2012

SET policy reduces risk of perinatal mortality in IVF and ICSI infants

A policy of single embryo transfer (SET) reduces the risk of perinatal mortality in infants born as a result of IVF and ICSI. The conclusion emerged from an analysis of more than 50,000 births recorded in the Australian and New Zealand Assisted Reproduction Technology Database between 2004 and 2008, where the introduction of an SET policy has been associated with a reduction in overall perinatal mortality for IVF and ICSI babies.

4 Jul 2012

Perinatal mortality risk in IVF reduced by single embryo transfer

4 Jul 2012

Scientists reprogram amniotic fluid cells without introduction of extra genes

Stem cells found in amniotic fluid can be transformed into a more versatile state similar to embryonic stem cells, according to a study published today in the journal Molecular Therapy. Scientists from Imperial College London and the UCL Institute of Child Health succeeded in reprogramming amniotic fluid cells without having to introduce extra genes.

4 Jul 2012

Cigarette smoke reduces production of Fallopian tube gene - BAD

Cigarette smoke reduces the production of a Fallopian tube gene known as "BAD", which helps explain the link between smoking and ectopic pregnancy. The finding, from scientists led by Drs Andrew Horne and Colin Duncan at the Medical Research Council (MRC) Centre for Reproductive Health in Edinburgh, UK, was described today at the annual meting of ESHRE (European Society of Human Reproduction and Embryology) in Istanbul.

4 Jul 2012