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Researchers shed light on basis of Parkinson’s disease and other ‘synucleinopathies’

Parkinson's disease (PD) and other "synucleinopathies" are known to be linked to the misfolding of alpha-synuclein protein in neurons.

27 Jan 2017

New gene therapy for Pompe disease may replace currently available treatments

After decades investigating a rare, life-threatening condition that cripples the muscles, Duke Health researchers have developed a gene therapy they hope could enhance or even replace the only FDA-approved treatment currently available to patients.

27 Jan 2017

Novel gene therapy restores partial hearing and balance in mice born with genetic deafness

Using a novel form of gene therapy, scientists from Harvard Medical School and the Massachusetts General Hospital have managed to restore partial hearing and balance in mice born with a genetic condition that affects both.

27 Jan 2017

Old tuberculosis drug improves impaired social behavior in autism mouse model

Reducing the function of the autism-associated gene Pcdh10 leads to impairments in social behavior, according to a study published in Biological Psychiatry.

26 Jan 2017

Researchers identify novel risk genes linked to bipolar disorder

Bipolar disorder (BD), characterized by mood swings between positive manic/hypomanic and negative/depressive states, is a common psychiatric disorder with a lifetime prevalence of ~1%.

26 Jan 2017

Johns Hopkins researchers create mature cardiomyocytes in the laboratory from stem cells

Generating mature and viable heart muscle cells from human or other animal stem cells has proven difficult for biologists.

26 Jan 2017

Adelaide researchers uncover new pathway that regulates spread of prostate cancer

University of Adelaide researchers have uncovered a new pathway which regulates the spread of prostate cancer around the body.

26 Jan 2017

Cancer cells proliferate by stealing energy from neighbouring cells, study finds

Researchers at the University of Oslo and Oslo University Hospital have discovered that cancer cells grow by stealing energy from neighbouring cells.

26 Jan 2017

Missing gene may cause kidney and urinary tract defects in people with DiGeorge syndrome

Loss of function of the CRKL gene causes kidney and urinary tract defects in people with DiGeorge syndrome, a multinational team of scientists led by Columbia University Medical Center has found.

25 Jan 2017

Synthetic molecule appears to reverse Alzheimer's-related neurological damage

Under ordinary circumstances, the protein tau contributes to the normal, healthy functioning of brain neurons. In some people, though, it collects into toxic tangles that damage brain cells.

25 Jan 2017

Researchers map genetic changes resulting from short bowel syndrome

Investigators at Children's Hospital Los Angeles, led by Tracy C. Grikscheit, MD, have mapped the genetic changes resulting from short bowel syndrome using a novel zebrafish model and by performing intensive gene sequencing.

25 Jan 2017

IU study shows how fruit fly growth shares biochemical similarities with cancer cells

Scientists who study a molecule known to play a role in certain types of cancers and neurodegenerative disorders have a powerful new tool to study this compound due to research conducted at Indiana University.

25 Jan 2017

HCI scientists uncover new way that bones get destroyed through breast cancer

Once breast cancer spreads through the body, it can degrade a patient's healthy bones, causing numerous problems. Scientists at Huntsman Cancer Institute at the University of Utah have identified a new way that bones get destroyed through cancer.

25 Jan 2017

Shorter chromosome 'caps' linked to higher burden of disease later in life

New research indicates that people who had more infections as babies harbor a key marker of cellular aging as young adults: the protective stretches of DNA which "cap" the ends of their chromosomes are shorter than in adults who were healthier as infants.

25 Jan 2017

Portable DNA sequencing device brought into North Hospitals to fight against anti-microbial resistance

A cutting edge, portable DNA sequencing device is being brought into North Hospitals for the first time by scientists fighting against anti-microbial resistance.

From Oxford Nanopore Technologies 25 Jan 2017

TSRI researchers develop first stable semisynthetic single-celled organism

Life’s genetic code has only ever contained four natural bases. These bases pair up to form two “base pairs”—the rungs of the DNA ladder—and they have simply been rearranged to create bacteria and butterflies, penguins and people. Four bases make up all life as we know it.

25 Jan 2017

Prenatal infection-induced epigenetic modifications may alter brain development in offspring

Maternal infection during pregnancy increases the risk for psychiatric disorders in the child, but the path between the two is something of a mystery.

25 Jan 2017

BRCA1 gene required for survival of blood forming stem cells, UT Southwestern study finds

Researchers at from the Harold C. Simmons Comprehensive Cancer Center have found that the BRCA1 gene is required for the survival of blood forming stem cells, which could explain why patients with BRCA1 mutations do not have an elevated risk for leukemia.

25 Jan 2017

Scientists discover new way to inhibit growth of glioblastoma

Scientists have found a way to inhibit the growth of glioblastoma, a type of brain cancer with low survival rates, by targeting a protein that drives growth of brain tumors, according to research from the Peter O'Donnell Jr. Brain Institute and Harold C. Simmons Comprehensive Cancer Center.

25 Jan 2017

UI biologists discover protein that appears to regulate chromosome movement

Before an egg becomes fertilized, sets of chromosomes must pair up to pass along genetic information. This happens within each reproductive cell, where separate chromosomes of male and female origin move toward each other and eventually join.

25 Jan 2017

Genes News and Research

Researchers shed light on basis of Parkinson’s disease and other ‘synucleinopathies’

New gene therapy for Pompe disease may replace currently available treatments

Novel gene therapy restores partial hearing and balance in mice born with genetic deafness

Old tuberculosis drug improves impaired social behavior in autism mouse model

Researchers identify novel risk genes linked to bipolar disorder

Johns Hopkins researchers create mature cardiomyocytes in the laboratory from stem cells

Adelaide researchers uncover new pathway that regulates spread of prostate cancer

Cancer cells proliferate by stealing energy from neighbouring cells, study finds

Missing gene may cause kidney and urinary tract defects in people with DiGeorge syndrome

Synthetic molecule appears to reverse Alzheimer's-related neurological damage

Researchers map genetic changes resulting from short bowel syndrome

IU study shows how fruit fly growth shares biochemical similarities with cancer cells

HCI scientists uncover new way that bones get destroyed through breast cancer

Shorter chromosome 'caps' linked to higher burden of disease later in life

Portable DNA sequencing device brought into North Hospitals to fight against anti-microbial resistance

TSRI researchers develop first stable semisynthetic single-celled organism

Prenatal infection-induced epigenetic modifications may alter brain development in offspring

BRCA1 gene required for survival of blood forming stem cells, UT Southwestern study finds

Scientists discover new way to inhibit growth of glioblastoma

UI biologists discover protein that appears to regulate chromosome movement

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