Genes News and Research

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Scientists develop new method to accurately determine gene expression in single cells

At Baylor College of Medicine, scientists have developed a method that allows them to accurately determine the genes expressed in single cells.

25 Jan 2017

Scientists sequence poisonous mushrooms to produce potential compounds for medicinal uses

A team of Michigan State University scientists has genetically sequenced two species of poisonous mushrooms, discovering that they can theoretically produce billions of compounds through one molecular assembly line.

24 Jan 2017

Timing of chemotherapy can have big effect on inflammation, study shows

The time of day that breast cancer chemotherapy drugs are given affects the amount of damaging inflammation in the body, a new study in mice suggests.

24 Jan 2017

New drugs that target neighbour proteins may help halt cancer progression

Cancer is caused by an accumulation of genetic changes in a cell, that overcome the normal checks and balances leading to uncontrolled growth. A complex, interacting network of proteins controls all of a cell's processes, from metabolism to growth and division.

24 Jan 2017

Researchers reveal central role of new key players in meiosis

Where would we be without meiosis and recombination? For a start, none of us sexually reproducing organisms would be here, because that's how sperm and eggs are made. And when meiosis doesn't work properly, it can lead to infertility, miscarriage, birth defects and developmental disorders.

24 Jan 2017

Study provides insights into molecular mechanisms of ZIKV infection

Zika virus (ZIKV) interferes with the cellular machinery controlling cell division and alters the expression of hundreds of genes guiding the formation and development of neurons and astrocytes, according to findings released on January 23rd 2017 at Scientific Reports.

24 Jan 2017

Tulane researchers discover cancer-causing role of protein thought to be tumor suppressor

Tulane University researchers have discovered that the protein PHLDB3, thought to be a potential tumor suppressor, actually allows cancer cells to thrive in pancreatic, prostate, colon, breast, lung, and other common cancers.

24 Jan 2017

Researchers find brain abnormalities in Zika virus infected fetuses

In a study to be presented Friday, Jan. 27, in the oral concurrent session at 1:15 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, researchers with the Baylor College of Medicine Department of Obstetrics and Gynecology, Houston, Texas partnered with the Maternal-Fetal Unit, CEDIFETAL, Centro de Diagnostico de Ultrasonido e Imagenes, CEDIUL, Barranquilla, Columbia and the Unidad De Fertildad Y Genetica De Cartagena, Cartagena de Indias, Columbia, to create the study, Characterization of brain malformations and volume assessment in fetuses with Zika Virus infection using MRI.

24 Jan 2017

Study identifies conserved role for Ovo protein in controlling germline development in mice and fruit flies

Germline cells are the only cells that develop into eggs or sperm, while somatic cells develop into the body. Progenitors of the germline, known as primordial germ cells (PGCs), differentiate into eggs or sperm after embryonic development.

24 Jan 2017

Researchers discover mutation hotspots that act like backseat drivers for breast cancer development

Researchers at the Wellcome Trust Sanger Institute have discovered 'hotspots' of mutations in breast cancer genomes, where mutations thought to be inactive 'passengers' in the genome have now been shown to possibly drive further cancerous changes.

23 Jan 2017

New stem cell method could lead to powerful treatments for skeletal system injuries

A recent study, affiliated with UNIST has developed a new method of repairing injured bone using stem cells from human bone marrow and a carbon material with photocatalytic properties, which could lead to powerful treatments for skeletal system injuries, such as fractures or periodontal disease.

23 Jan 2017

Fetal genomic sequencing could enhance detection rate of genetic findings, study shows

In a study to be presented Thursday, Jan. 26, in the oral plenary session at 8 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, researchers with the Columbia University Medical Center in New York found that, in preliminary data, fetal genomic (whole exome) sequencing (WES) as a diagnostic test for women with pregnancies complicated by major fetal congenital anomalies increased the detection rate of genetic findings by between 10 to 30 percent.

23 Jan 2017

Study looks at use of evolutionary triangulation to refine results from genetic studies of preterm birth

In a study to be presented Thursday, Jan. 26, in the oral concurrent session at 1:15 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, researchers verified genetic results from one large study of women with spontaneous preterm birth, and highlighted 13 key genes in both mothers and babies which may be involved in preterm birth while also identifying 123 genes as top candidates for further study.

23 Jan 2017

Bruker is to be key International Phenome Centre Network corporate partner for NMR Technologies and SOPs

The International Phenome Centre Network (IPCN), founded by Imperial College London and more than a dozen international partners in Australia, Canada, China, Japan, Singapore, Taiwan, the US, and the UK (www.phenomenetwork.org), was launched officially this week at the 2016 World Innovation Summit for Health (WISH) conference in Doha, Qatar. This global network is a critical link between leading research centers across the world and will support research into some of today’s most pressing global health challenges.

From Bruker 23 Jan 2017

Sapientia genome analysis software by Congenica could cut costs and save lives

Whole genome analysis (WGA) enables rapid diagnosis of rare disease, ensuring that an appropriate course of management and treatment can be administered, possibly within days for acute neonatal cases, cutting the cost of intensive care and potentially saving lives. Rapid diagnosis is one of the many benefits of using the Sapientia™ genome analysis and interpretation platform that Dr Nick Lench, Chief Operating Officer of Congenica, will be discussing at Precision Medicine World Conference (PMWC) 2017 on January 23rd at 3.15pm.

23 Jan 2017

Researchers uncover mechanism of resistance used by triple negative breast cancer

Breast cancer cells are evasive, finding ways to bypass drugs designed to stop their unchecked growth.

20 Jan 2017

Researchers identify new principle for how epigenetic changes can occur

In a new study, researchers at Uppsala University have found evidence of a new principle for how epigenetic changes can occur. The principle is based on an enzyme, tryptase, that has epigenetic effects that cause cells to proliferate in an uncontrolled manner.

20 Jan 2017

Salk Institute researchers reveal how to curb immune enthusiasm

Normally when we think of viruses, from the common cold to HIV, we want to boost people's immunity to fight them.

20 Jan 2017

Precision medicine advances diagnosis and treatment of children with brain tumors

Precision medicine - in which diagnosis and treatments are keyed to the genetic susceptibilities of individual cancers - has advanced to the point where it can now impact the care of a majority of children with brain tumors, a new study by investigators at Dana-Farber/Boston Children's Cancer and Blood Disorders Center suggests.

20 Jan 2017

NYU Langone scientists discover mechanism behind many disease-related genetic deletions

Scientists at NYU Langone Medical Center have discovered the mechanisms behind a genetic change known to cause a set of related diseases.

20 Jan 2017

Genes News and Research

Scientists develop new method to accurately determine gene expression in single cells

Scientists sequence poisonous mushrooms to produce potential compounds for medicinal uses

Timing of chemotherapy can have big effect on inflammation, study shows

New drugs that target neighbour proteins may help halt cancer progression

Researchers reveal central role of new key players in meiosis

Study provides insights into molecular mechanisms of ZIKV infection

Tulane researchers discover cancer-causing role of protein thought to be tumor suppressor

Researchers find brain abnormalities in Zika virus infected fetuses

Study identifies conserved role for Ovo protein in controlling germline development in mice and fruit flies

Researchers discover mutation hotspots that act like backseat drivers for breast cancer development

New stem cell method could lead to powerful treatments for skeletal system injuries

Fetal genomic sequencing could enhance detection rate of genetic findings, study shows

Study looks at use of evolutionary triangulation to refine results from genetic studies of preterm birth

Bruker is to be key International Phenome Centre Network corporate partner for NMR Technologies and SOPs

Sapientia genome analysis software by Congenica could cut costs and save lives

Researchers uncover mechanism of resistance used by triple negative breast cancer

Researchers identify new principle for how epigenetic changes can occur

Salk Institute researchers reveal how to curb immune enthusiasm

Precision medicine advances diagnosis and treatment of children with brain tumors

NYU Langone scientists discover mechanism behind many disease-related genetic deletions

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