Genes News and Research

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COGENT scientists uncover genes responsible for cognitive ability

An international team of scientists, led by Todd Lencz, PhD, professor at The Feinstein Institute for Medical Research at Northwell Health and Hofstra Northwell School of Medicine, have unlocked some of the genes responsible for cognitive ability.

17 Jan 2017

Epigenetic changes drive successful metastases of pancreatic cancer cells

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

17 Jan 2017

Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

Each day, more than 1,600 people die from cancer in the US, and 450 in the UK, mostly because the disease has spread beyond a stage when surgery is an effective cure and has become resistant to therapy. Despite decades of research, understanding why cancer cells become invasive has remained shrouded in mystery.

17 Jan 2017

Drug-resistant deadly bacteria more widespread than previously thought, study finds

A family of highly drug-resistant and potentially deadly bacteria may be spreading more widely--and more stealthily -- than previously thought, according to a new study from Harvard T.H. Chan School of Public Health and the Broad Institute of MIT and Harvard.

17 Jan 2017

Knowledge bank approach could help find best treatment option for AML patients

An international collaboration led by clinical researchers at the Wellcome Trust Sanger Institute has shown proof-of-concept that truly personalised therapy will be possible in the future for people with cancer.

17 Jan 2017

Endogenous retroviruses may have played significant role in development of the brain

Over millions of years retroviruses have been incorporated into our human DNA, where they today make up almost 10 per cent of the total genome.

12 Jan 2017

Inhibition of EZH2 protein could be new strategy to treat multiple myeloma

In a study published in the scientific journal Oncotarget, researchers from Uppsala University show how the protein EZH2 affects the development of multiple myeloma, and that inhibition of EZH2 could be used as a new strategy to treat the disease.

12 Jan 2017

Researchers finding way to manipulate signals in bacteria to reduce infections

The University of Illinois at Chicago College of Pharmacy has received a five-year, $1.25 million federal grant to continue its research into how bacteria that cause streptococcal infections can be manipulated.

12 Jan 2017

Epigenetic modification may be cause of adult throat cancers linked to alcohol, tobacco use

A team of researchers at the Research Institute of the McGill University Health Centre has found an epigenetic modification that might be the cause of 15% of adult cancers of the throat linked to alcohol and tobacco use.

12 Jan 2017

Genes implicated in rare pediatric epilepsy contribute to common forms of disorder, study finds

An international study led by Columbia University Medical Center and NewYork-Presbyterian researchers has found that several genes previously implicated only in rare, severe forms of pediatric epilepsy also contribute to common forms of the disorder.

12 Jan 2017

CSHL scientists create first model of genetically induced obesity in fruit flies

Why do people become obese? Poor dietary choices and overeating seem like clear causes, but what is at the root of these behaviors? Significantly overweight people may be genetically predisposed to be affected disproportionately when faced with the ready availability of calorie-laden treats.

11 Jan 2017

Study shows how phage-resistant cells become susceptible upon co-incubation with sensitive bacteria

Bacteriophages (phages) are probably the most abundant entities in nature, often exceeding bacterial densities by an order of magnitude.

11 Jan 2017

Illumina and IBM join forces to grow accessibility to genome data interpretation

IBM Watson Health and Illumina, Inc. today announced a groundbreaking partnership to expand access to genome data interpretation by integrating Watson for Genomics into Illumina’s BaseSpace Sequence Hub and tumor sequencing process. The collaboration is designed to help standardize and simplify genomic data interpretation.

From Illumina, Inc. 11 Jan 2017

Roswell Park study provides new insights into gene mutations that can lead to cancer

Predisposition to cancer and cancer progression can result from gene mutations that cause elevated rates of genetic damage.

11 Jan 2017

Roswell Park researchers identify gene signatures that may help predict fatal prostate cancers

Standard therapy for prostate cancer, the third-leading cause of cancer-related deaths in American men, is based on blocking androgens, the male sex hormones.

11 Jan 2017

Real-time study of medaka fish aboard ISS sheds light on bone metabolism under microgravity

Tokyo Institute of Technology research: Gravitational biology: Real time imaging and transcriptome analysis of medaka aboard space station

11 Jan 2017

Study strengthens therapeutic potential for niacin-based diet in treatment of Parkinson's disease

People with certain forms of early-onset Parkinson's disease may benefit from boosting the amount of niacin in their diet, according to new research from the University of Leicester.

11 Jan 2017

Researchers identify new subgroup of cervical cancers with different genetic features

A team of University of South Carolina scientists led by Carolyn Banister and Phillip Buckhaults has identified a new subtype of cervical cancer that, like most cervical cancers, is triggered by human papillomavirus (HPV) but whose growth is not directed by the virus, suggesting that therapy targeting these tumors' distinct genomic pathways may improve patient outcomes over standard treatment.

11 Jan 2017

Surveillance machinery in cells recognizes and destroys defective genetic material, research shows

New research out of Case Western Reserve University School of Medicine describes a mechanism by which an essential quality control system in cells identifies and destroys faulty genetic material. The findings were published online December 23 in Nature Communications.

11 Jan 2017

MGH researchers identify gene mutations linked to rare congenital condition involving lack of nose

Researchers from Massachusetts General Hospital led a large, international research team that has identified gene mutations associated with a rare congenital condition involving the absence of a nose and often accompanied by defects involving the eye and reproductive systems.

11 Jan 2017

Genes News and Research

COGENT scientists uncover genes responsible for cognitive ability

Epigenetic changes drive successful metastases of pancreatic cancer cells

Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

Drug-resistant deadly bacteria more widespread than previously thought, study finds

Knowledge bank approach could help find best treatment option for AML patients

Endogenous retroviruses may have played significant role in development of the brain

Inhibition of EZH2 protein could be new strategy to treat multiple myeloma

Researchers finding way to manipulate signals in bacteria to reduce infections

Epigenetic modification may be cause of adult throat cancers linked to alcohol, tobacco use

Genes implicated in rare pediatric epilepsy contribute to common forms of disorder, study finds

CSHL scientists create first model of genetically induced obesity in fruit flies

Study shows how phage-resistant cells become susceptible upon co-incubation with sensitive bacteria

Illumina and IBM join forces to grow accessibility to genome data interpretation

Roswell Park study provides new insights into gene mutations that can lead to cancer

Roswell Park researchers identify gene signatures that may help predict fatal prostate cancers

Real-time study of medaka fish aboard ISS sheds light on bone metabolism under microgravity

Study strengthens therapeutic potential for niacin-based diet in treatment of Parkinson's disease

Researchers identify new subgroup of cervical cancers with different genetic features

Surveillance machinery in cells recognizes and destroys defective genetic material, research shows

MGH researchers identify gene mutations linked to rare congenital condition involving lack of nose

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