Genes News and Research

RSS

Parental obesity may increase children's risk for developmental delays, NIH study suggests

Children of obese parents may be at risk for developmental delays, according to a study by researchers at the National Institutes of Health.

2 Jan 2017

AAV-based gene therapy to treat liver disorders advances into human testing

Liver-directed gene therapy delivered using adeno-associated viral (AAV) vectors to treat diseases such as hemophilia have advanced into human testing.

30 Dec 2016

Study examines how ApoE gene may function differently in infectious environment

You've likely heard about being in the right place at the wrong time, but what about having the right genes in the wrong environment? In other words, could a genetic mutation (or allele) that puts populations at risk for illnesses in one environmental setting manifest itself in positive ways in a different setting?

30 Dec 2016

New active pharmaceutical ingredient may help against severe forms of testicular cancer

A new active pharmaceutical ingredient may help against severe forms of testicular cancer, which only respond inadequately to other therapies.

30 Dec 2016

Mutations linked to endometrial cancer can be found in uterine lavage fluid before cancer diagnosis

Mutations that have been linked to endometrial cancer can be found in the uterine lavage fluid of pre- and post-menopausal women both with and without detectable cancer, according to a study published in PLOS Medicine by John Martignetti, MD, PhD of the Icahn School of Medicine at Mount Sinai and colleagues.

30 Dec 2016

Genetic and environmental factors affect language-related brain activities

Osaka University-led researchers examine brain activity in monozygotic and dizygotic Japanese twins and show that environmental and genetic influences affect language-related brain activities in left frontal area of the brain.

30 Dec 2016

IQWiG investigates benefit of biomarker tests to support decision on adjuvant chemotherapy

The German Institute for Quality and Efficiency in Health Care (IQWiG) investigated the benefit of biomarker tests to support the decision for or against adjuvant systemic chemotherapy in certain breast cancer patients, that is, women with primary hormone receptor-positive, HER2-negative breast cancer and up to 3 affected lymph nodes.

30 Dec 2016

Studies in non-human primates provide more predictive results in genetic causes of blindness

Many gene therapy-based approaches are in development to combat genetic and other causes of blindness and vision loss, and much can be learned about the safety and effectiveness of these promising new therapies by studying them first in non-human primates before initiating clinical trials, as shown by the results of a study published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

29 Dec 2016

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity.

28 Dec 2016

Myc genes play key role in self-renewal of spermatogonial stem cells

Sperm are constantly replenished in the adult male body. Understanding the workings of stem cells responsible for this replenishment is expected to shed light on why male fertility diminishes with age, and possibly lead to new treatments for infertility.

28 Dec 2016

Research reveals how microbial context during infectious disease can compromise antibiotic therapy

Bacteria that are susceptible to antibiotics can survive when enough resistant cells around them are expressing an antibiotic-deactivating factor.

28 Dec 2016

Scientists report new molecular mechanism that could be cause of autoimmune diseases

Scientists at the Immunology Frontier Research Center (IFReC), Osaka University, Japan, report a new molecular mechanism that could explain the cause of some autoimmune diseases.

27 Dec 2016

Researchers explore how neuronal activity influences CREB dynamics

Neuronal activity mediates the formation of neuronal circuits in the cerebral cortex. These processes are regulated by the transcription factor CREB, which regulates gene expression in neuronal activity-dependent processes.

27 Dec 2016

Potential drug could become first effective treatment option for Prader-Willi syndrome

Duke Health researchers have identified a drug-like small molecule that, in animal experiments, appears to be an effective treatment for a genetic disorder called Prader-Willi syndrome.

27 Dec 2016

New research points to lncRNA's key role in helping control cellular processes

Scientific research over the past decade has concentrated almost exclusively on the 2 percent of the genome's protein coding regions, virtually ignoring the other 98 percent, a vast universe of non-coding genetic material previously dismissed as nothing more than 'junk.'

27 Dec 2016

Experimental drug improves survival, growth outcomes in mouse model of Prader-Willi syndrome

Drugs capable of activating silenced genes improve survival and growth outcomes in a mouse model of Prader-Willi syndrome, a rare and incurable childhood disease, according to a study funded by the National Institutes of Health.

27 Dec 2016

CSHL researcher-inventor hails FDA approval of new SMA drug

Within a week of Christmas day, a drug called nusinersen will be in the hands of doctors across the nation, who will use it, most urgently, to treat young children with a severe and potentially fatal illness called spinal muscular atrophy (SMA).

26 Dec 2016

Johns Hopkins scientists find link between sleep/wake cycles and core body temperature

A clump of just a few thousand brain cells, no bigger than a mustard seed, controls the daily ebb and flow of most bodily processes in mammals -- sleep/wake cycles, most notably.

23 Dec 2016

Genomic sequencing reveals new insights into major shigellosis outbreaks in California

In a study that could have significant impact on how disease outbreaks are managed, researchers at UC Davis and the California Department of Public Health have sequenced and analyzed genomes from Shigella sonnei (S. sonnei) bacteria associated with major shigellosis outbreaks in California in 2014 and 2015.

23 Dec 2016

Caltech scientists develop simple way to visualize gene expression with MRI

Genes tell cells what to do -- for example, when to repair DNA mistakes or when to die--and can be turned on or off like a light switch.

23 Dec 2016

Genes News and Research

Parental obesity may increase children's risk for developmental delays, NIH study suggests

AAV-based gene therapy to treat liver disorders advances into human testing

Study examines how ApoE gene may function differently in infectious environment

New active pharmaceutical ingredient may help against severe forms of testicular cancer

Mutations linked to endometrial cancer can be found in uterine lavage fluid before cancer diagnosis

Genetic and environmental factors affect language-related brain activities

IQWiG investigates benefit of biomarker tests to support decision on adjuvant chemotherapy

Studies in non-human primates provide more predictive results in genetic causes of blindness

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Myc genes play key role in self-renewal of spermatogonial stem cells

Research reveals how microbial context during infectious disease can compromise antibiotic therapy

Scientists report new molecular mechanism that could be cause of autoimmune diseases

Researchers explore how neuronal activity influences CREB dynamics

Potential drug could become first effective treatment option for Prader-Willi syndrome

New research points to lncRNA's key role in helping control cellular processes

Experimental drug improves survival, growth outcomes in mouse model of Prader-Willi syndrome

CSHL researcher-inventor hails FDA approval of new SMA drug

Johns Hopkins scientists find link between sleep/wake cycles and core body temperature

Genomic sequencing reveals new insights into major shigellosis outbreaks in California

Caltech scientists develop simple way to visualize gene expression with MRI

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics