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How does temperature affect host responses to SARS-CoV-2 and IAV infection in human nasal epithelial cells?

A new preprint examines the response to these pathogens in the nose, which is the primary portal of entry for both.

13 Mar 2023

ACE2: its diverse functions, relationship with SARS-CoV-2, and the implications for COVID-19 disease sequelae

Researchers assessed the role of ACE2 in the COVID-19 pandemic.

9 Mar 2023

How SARS-CoV-2 infection affects acute ischemic stroke outcomes

A recent PLOS ONE journal study evaluated the impact of COVID-19 on neurological outcomes in acute ischemic stroke patients.

6 Mar 2023

Frequent zoonotic spillover of diverse sarbecoviruses in communities interacting with wildlife

A new study published in the International Journal of Infectious Diseases surveyed communities in rural Myanmar to study their exposure to sarbecoviruses and interaction with wildlife.

6 Mar 2023

Researchers use spatial single-cell transcriptome technique to examine immune signatures of SARS-CoV-2-infected lungs

The study findings demonstrate the power of spatial single-cell transcriptomics in studying COVID-19 lung pathology and other health and disease conditions.

1 Mar 2023

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

Omicron BTIs induce durable neutralizing immune responses by recalling cross-reactive and vaccine-induced memory B lymphocytes.

1 Mar 2023

Researchers develop protein-based nanoparticles to neutralize SARS-CoV2 virus

Nanomaterials inspired by amyloid proteins are gaining interest in nanotechnology, due to their modularity, controlled self-assembly and stability.

28 Feb 2023

Study analyzes the potential of a natural amino acid as new way to cure COVID-19

After more than two years since its discovery, six million deaths, and half a billion reported cases, there is still no effective cure for COVID-19. Even though vaccines have lowered the impact of outbreaks, patients that contract the disease can only receive supportive care while they wait for their own body to clear the infection.

24 Feb 2023

Study shows antibody-dependent SARS-CoV-2 transmission and pathogenesis

Researchers reported that some monoclonal nAbs directed against distinct RBD epitopes nested inside the SARS-CoV-2 S could substitute ACE2 as a receptor and support fusion between viral and host cell membranes facilitating viral infectivity.

23 Feb 2023

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Researchers assessed the impact of SARS-CoV-2 spike NTD incorporation into the RBD protein vaccine.

22 Feb 2023

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Researchers used a non-human primate model to show that Sotrovimab, a commercial mAb also known as Xevudy, was fully effective against SARS-CoV-2 Omicron BA.5 sub-lineage and its derivatives, such as BQ.1.1.

17 Feb 2023

Smoking and vaping may put healthy young people at risk of severe COVID

The levels of some ADAM17 targets were elevated in the plasma of tobacco cigarette smokers as compared to non-smokers.

15 Feb 2023

New insights into the driving factors of COVID-19 dynamics in England

In a recent study posted to the medRxiv* preprint server, researchers provided quantitative estimates of population-level drivers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and infection severity by fitting coronavirus disease 2019 (COVID-19) epidemiological surveillance data from England into dynamic transmission models.

15 Feb 2023

Comparative study on retinoic acid-inducible gene-I of humans and bats

In a recent study posted to the bioRxiv* preprint server, researchers cloned and functionally characterized the virus ribonucleic acid (RNA) sensor, retinoic acid-inducible gene-I (RIG-I), from the microbat Myotis daubentonii (Yangochiroptera suborder) and the megabat Rousettus aegyptiacus (Yinpterochiroptera suborder), and compared them to the human ortholog.

15 Feb 2023

ACE2 News and Research

How does temperature affect host responses to SARS-CoV-2 and IAV infection in human nasal epithelial cells?

ACE2: its diverse functions, relationship with SARS-CoV-2, and the implications for COVID-19 disease sequelae

How SARS-CoV-2 infection affects acute ischemic stroke outcomes

Frequent zoonotic spillover of diverse sarbecoviruses in communities interacting with wildlife

Researchers use spatial single-cell transcriptome technique to examine immune signatures of SARS-CoV-2-infected lungs

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

Researchers develop protein-based nanoparticles to neutralize SARS-CoV2 virus

Study analyzes the potential of a natural amino acid as new way to cure COVID-19

Study shows antibody-dependent SARS-CoV-2 transmission and pathogenesis

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Smoking and vaping may put healthy young people at risk of severe COVID

New insights into the driving factors of COVID-19 dynamics in England

Comparative study on retinoic acid-inducible gene-I of humans and bats

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

Omicron BQ and XBB subvariants most resistant viruses to monoclonal antibodies

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Smoking tobacco and vaping e-cigarettes may increase healthy young people's risk for severe COVID

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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