Amyloid Plaque News and Research

RSS

Multi-gene test found to be better at identifying older adults at risk for Alzheimer's

A new test that combines the effects of more than two dozen genetic variants, most associated by themselves with only a small risk of Alzheimer's disease, does a better job of predicting which cognitively normal older adults will go on to develop Alzheimer's dementia than testing only for the well-known genetic variant APOE E4, a scientific team led by researchers at UC San Francisco and UC San Diego has found.

22 Sep 2017

High-definition eye scan could reveal crucial warning signs of Alzheimer's disease

Cedars-Sinai neuroscience investigators have found that Alzheimer's disease affects the retina – the back of the eye – similarly to the way it affects the brain.

17 Aug 2017

Study reveals early indication of Alzheimer’s in adults with normal cognition

A new study led by the Keck School of Medicine of University of Southern California (USC) reveals that older adults with elevated levels of brain-clogging plaques, yet normal cognition, experience faster mental decline, suggestive of Alzheimer's disease. The study published in The Journal of the American Medical Association on June 13 presented the earliest precursor—the toxic and sticky protein as part of the disease, before symptoms arise.

15 Jun 2017

USC scientists illuminate impact of early brain-clogging plaques on Alzheimer's disease

Older adults with elevated levels of brain-clogging plaques -- but otherwise normal cognition -- experience faster mental decline suggestive of Alzheimer's disease, according to a new study led by the Keck School of Medicine of USC that looked at 10 years of data.

13 Jun 2017

Researchers measure spread of tau protein in the brains of Alzheimer’s patients

In a new study presented in Molecular Psychiatry, researchers at Karolinska Institutet have measured how deposits of the pathological protein tau spread through the brain over the course of Alzheimer's disease.

16 May 2017

New humanized model enables better characterization of Alzheimer's pathology

Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures.

24 Feb 2017

Study opens door to new opportunities for preventing and treating Alzheimer's disease

New research from Lund University in Sweden has shown that intestinal bacteria can accelerate the development of Alzheimer's disease.

11 Feb 2017

Gut bacteria can accelerate development of Alzheimer’s disease, research shows

New research from Lund University in Sweden has shown that intestinal bacteria can accelerate the development of Alzheimer's disease. According to the researchers behind the study, the results open up the door to new opportunities for preventing and treating the disease.

10 Feb 2017

Air pollution may greatly increase chance of dementia in older women

Tiny air pollution particles -- the type that mainly comes from power plants and automobiles -- may greatly increase the chance of dementia, including Alzheimer's disease, according to USC-led research.

31 Jan 2017

Aerobic exercise could help wounded warriors recover from mild traumatic brain injury

Improvised explosive devices and associated blast injuries have left over 350,000 U.S. service members in Iraq and Afghanistan with an invisible wound: traumatic brain injury.

25 Jan 2017

TSRI scientists identify potential therapeutic target for age- or Alzheimer's disease-related memory deficits

Scientists from the Florida campus of The Scripps Research Institute have made an important discovery toward the development of drugs to treat age-related memory loss in diseases like Alzheimer's.

7 Dec 2016

PET imaging can accurately identify difficult-to-diagnose cardiac amyloidosis

Reston, Virginia - Researchers at Princess Alexandra Hospital, Brisbane, Australia, have demonstrated that cardiac amyloidosis (abnormal deposits of proteins in the heart), which is notoriously difficult to diagnose, can be visualized noninvasively with positron emission tomography (PET) using the radiotracer fluorine-18 (F-18)-florbetaben.

1 Nov 2016

Icelandic people more likely to carry novel rare genetic variant linked to risk of Alzheimer's disease

People with Icelandic heritage are more likely to carry a novel rare mutation in the TM2D3 gene, which leads to greater risk for Alzheimer's disease, based on a new study published October 14th, 2016 in PLOS Genetics by Johanna Jakobsdottir of the Icelandic Heart Association, Sven van der Lee of Erasmus University in Rotterdam, and colleagues.

17 Oct 2016

Monoclonal antibody removes brain amyloid plaques in patients with Alzheimer's disease

Scientists at Neurimmune today described results from the Phase 1b PRIME clinical trial of the monoclonal antibody aducanumab.

1 Sep 2016

New mouse model reveals how Alzheimer's causes dementia

Using a novel, newly developed mouse model that mimics the development of Alzheimer's disease in humans, Johns Hopkins researchers say they have been able to determine that a one-two punch of major biological "insults" must occur in the brain to cause the dementia that is the hallmark of the disease.

4 Jul 2016

Research highlights association of western diet with Alzheimer's disease

Recent research has established associations between certain environmental factors, including eating a western diet and being sedentary, with an increased susceptibility to Alzheimer's disease. In fact, it is estimated that a combination of diet and inactivity contributes to as many as 25% of Alzheimer's cases. Nonetheless, little is known about the exact disease mechanisms and how or why this increasingly common middle-age lifestyle can play such a big role in subsequent cognitive function.

7 Mar 2016

Immune cells may play greater role in Alzheimer's disease than originally thought

Immune cells that normally help us fight off bacterial and viral infections may play a far greater role in Alzheimer's disease than originally thought, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

24 Feb 2016

Experimental drug candidate aimed at combating Alzheimer's disease has anti-aging effects

Salk Institute researchers have found that an experimental drug candidate aimed at combating Alzheimer's disease has a host of unexpected anti-aging effects in animals.

13 Nov 2015

IU-led scientists discover new gene that increases Alzheimer's disease risk

In a newly published study, a multi-institutional team led by scientists at the Indiana University School of Medicine have discovered an immune system gene associated with higher rates of amyloid plaque buildup in the brains of Alzheimer's patients and older adults at risk for the disease.

6 Oct 2015

New drug shows promise in slowing Alzheimer’s disease

New research findings have fuelled hopes of a drug that can slow down the progression of Alzheimer’s disease.

23 Jul 2015