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Rare variants in high-risk autism gene can alter architecture and organization of neurons, study finds

Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that rare variants in the ANK2 gene, consistently found in individuals with autism spectrum disorder (ASD), can alter architecture and organization of neurons, potentially contributing to autism and neurodevelopmental comorbidities.

29 Nov 2021

UVA researchers develop a noninvasive surgical approach to remove faulty brain circuits

University of Virginia School of Medicine researchers have developed a noninvasive way to remove faulty brain circuits that could allow doctors to treat debilitating neurological diseases without the need for conventional brain surgery.

25 Nov 2021

Scientists unravel near-atomic-scale structure of depression-linked brain receptor

Scientists at Scripps Research, Florida have determined the near-atomic-scale structure of an unusual brain-cell receptor called GPR158, which has been linked to depression and anxiety.

20 Nov 2021

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type C1 (NPC1), a rare genetic disorder affecting children and adolescents, suggests a study in mice by scientists at the National Institutes of Health.

20 Nov 2021

Researchers receive $8.9 million grant to study the gut-brain connection in Parkinson’s disease

Dr. Michael Kaplitt, a professor of neurological surgery at Weill Cornell Medicine and a longtime leader in developing cutting-edge surgical therapies for movement disorders, leads a team that has been awarded a three-year, $8.9 million grant from the Aligning Science Across Parkinson's (ASAP) initiative.

26 Oct 2021

UVA researchers identify an unknown trigger for epilepsy seizures

Researchers at the University of Virginia School of Medicine have uncovered how problems in cortical microcircuits in the brain can trigger epilepsy seizures.

20 Oct 2021

Long stays in space appear to cause brain damage

Spending a long time in space appears to cause brain damage. This is shown by a study of five Russian cosmonauts who had stayed on the International Space Station.

12 Oct 2021

New technology shows great promise for early diagnosis of Alzheimer’s disease

A technology developed by scientists at Lawrence Berkeley National Laboratory (Berkeley Lab) shows great promise for diagnosing Alzheimer's disease before symptoms arise, potentially changing the course of research and treatment for this condition, which affects millions of people worldwide and is estimated to be the sixth leading cause of death in the United States.

7 Oct 2021

Mouse brain atlas may help understand the complex circuits of the human brain

The circuits of the human brain contain more than 100 billion neurons, each linked to many other neurons via thousands of synaptic connections, resulting in a three-pound organ that is profoundly more complex than the sum of its innumerable parts.

7 Oct 2021

Scientists make inroads into creating an atlas of the mouse brain

It takes billions of cells to make a human brain, and scientists have long struggled to map this complex network of neurons.

6 Oct 2021

Toxic fatty acids trigger cell death in damaged neurons

Cells that normally nourish healthy brain cells called neurons release toxic fatty acids after neurons are damaged, a new study in rodents shows.

6 Oct 2021

Detailed atlas of the mammalian primary motor cortex will provide a springboard for future research

The NIH Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative Cell Census Network (BICCN) has unveiled an atlas of cell types and an anatomical neuronal wiring diagram for the mammalian primary motor cortex, derived from detailed studies of mice, monkeys, and humans.

6 Oct 2021

Stringent lineage tracing is vital for nerve cell regeneration studies

UT Southwestern stem cell scientists find that stringent lineage tracing is crucial for studies of nerve cell regeneration. Their results, which are published in Cell, show that this tracing is far from routine in the field and suggest that earlier studies reporting "striking" regeneration results must be reexamined.

29 Sep 2021

Study identifies probable cause of Alzheimer’s disease

Ground-breaking new Curtin University-led research has discovered a likely cause of Alzheimer's disease, in a significant finding that offers potential new prevention and treatment opportunities for Australia's second-leading cause of death.

16 Sep 2021

An existing drug may function as targeted therapy for ALL in children

A new study from Linköping University has shown that the tumour-inhibiting gene TET2 is silenced in a large fraction of cases of acute lymphoblastic leukemia (ALL) in children.

25 Aug 2021

Brain memory signals may influence blood sugar levels, rat study finds

A set of brain signals known to help memories form may also influence blood sugar levels, finds a new study in rats.

11 Aug 2021

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

Researchers in Singapore have discovered that brain cells cannot maintain the cholesterol-rich myelin sheath that protects and insulates neurons in the absence of a protein called TDP-43.

4 Aug 2021

Graduate student receives NIH grant to study specific molecule’s role in healthy neurodevelopment

Raymundo Hernandez was always drawn to psychology - that is, until he took his first neurobiology class as an undergraduate.

20 Jul 2021

Study: Gene editing therapy for early-stage Huntington’s disease may have long-lasting benefits

In a new study on mice, Johns Hopkins Medicine researchers report that using MRI scans to measure blood volume in the brain can serve as a noninvasive way to potentially track the progress of gene editing therapies for early-stage Huntington's disease, a neurodegenerative disorder that attacks brain cells.

7 Jul 2021

Research reveals new class of neurons that links face perception to long-term memory

Scientists have long searched in vain for a class of brain cells that could explain the visceral flash of recognition that we feel when we see a very familiar face, like that of our grandmothers.

2 Jul 2021

Brain Cell News and Research

Rare variants in high-risk autism gene can alter architecture and organization of neurons, study finds

UVA researchers develop a noninvasive surgical approach to remove faulty brain circuits

Scientists unravel near-atomic-scale structure of depression-linked brain receptor

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Researchers receive $8.9 million grant to study the gut-brain connection in Parkinson’s disease

UVA researchers identify an unknown trigger for epilepsy seizures

Long stays in space appear to cause brain damage

New technology shows great promise for early diagnosis of Alzheimer’s disease

Mouse brain atlas may help understand the complex circuits of the human brain

Scientists make inroads into creating an atlas of the mouse brain

Toxic fatty acids trigger cell death in damaged neurons

Detailed atlas of the mammalian primary motor cortex will provide a springboard for future research

Stringent lineage tracing is vital for nerve cell regeneration studies

Study identifies probable cause of Alzheimer’s disease

An existing drug may function as targeted therapy for ALL in children

Brain memory signals may influence blood sugar levels, rat study finds

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

Graduate student receives NIH grant to study specific molecule’s role in healthy neurodevelopment

Study: Gene editing therapy for early-stage Huntington’s disease may have long-lasting benefits

Research reveals new class of neurons that links face perception to long-term memory

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