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Tailored gene therapy dramatically reduces childhood epilepsy seizures in trial

SCN2A‑related developmental epileptic encephalopathy (DEE) is a rare, severe form of childhood epilepsy and one of the most common causes of monogenic autism.

21 Jul 2026

Researchers uncover brain target to counter fentanyl-induced slow breathing

Fentanyl causes symptoms that can lead to death from overdose. One of these symptoms is slow breathing, which deprives drug users of oxygen.

20 Jul 2026

SORLA protein may protect the brain from toxic tau tangles

Alzheimer's disease and many other forms of neurodegeneration share a common culprit. In these diseases, tau proteins that normally stabilize neuronal microtubule filaments within our nervous system networks instead form noxious knots and gradually disrupt the circuits they would otherwise preserve.

17 Jul 2026

ECT-like brain stimulation triggers unexpected nuclear reprogramming in mature neurons

Nearly 90 years after Ugo Cerletti and Lucio Bini introduced electroconvulsive therapy (ECT), brain stimulation therapies such as ECT and Repetitive Transcranial Magnetic Stimulation (rTMS) are common in psychiatry because they are highly effective for treating depression and schizophrenia, yet their cellular mechanisms remain poorly understood

17 Jul 2026

Scientists discover master regulator gene network behind complex psychiatric disorders

A study by the University of Barcelona has identified nearly 20 genes that could contribute to some people being more susceptible to depression, anxiety and traits such as irritability and neuroticism.

17 Jul 2026

Researchers identify new genetic pathway driving epilepsy and seizures

Researchers have uncovered a novel biological pathway that can lead to seizures when disrupted. The findings also provide a new approach to improve the diagnosis of epilepsy, for which a genetic cause cannot be found in about 50 % of individuals with the condition

16 Jul 2026

Brain’s immune cells play key role in maintaining stability of neuronal networks in Alzheimer's disease

Researchers at Trinity College Dublin have discovered that microglia – the main immune cells of the brain – play a critical role in maintaining the stability of neuronal networks in Alzheimer's disease.

15 Jul 2026

New photoswitchable drugs restore light perception in blind animals

Blinding diseases caused by the degeneration of photoreceptors, such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP), affect 200 million people worldwide and represent the leading causes of visual impairment and blindness.

15 Jul 2026

New review highlights astrocytes' role in chronic traumatic encephalopathy

Researchers from Kansas City University School of Medicine have published a scoping review examining the role of astrocytes in chronic traumatic encephalopathy (CTE).

14 Jul 2026

Imaging technique uncovers how copper imbalance may contribute to neurodegenerative diseases

Using a groundbreaking imaging technique, a University of Houston chemist is uncovering how copper imbalances in the body may contribute to neurodegenerative diseases such as Alzheimer's, Parkinson's and ALS.

13 Jul 2026

New stem cell therapy offers hope for chronic spinal injury

New research presented today at the International Society for Stem Cell Research (ISSCR) 2026 Annual Meeting highlights a significant step toward developing a stem cell-based treatment for chronic spinal cord injury (SCI), a condition for which no effective restorative therapy currently exists.

11 Jul 2026

Stem cell-derived dopaminergic cell transplantation shows encouraging results for Parkinson's disease

The International Society for Stem Cell Research (ISSCR) today announced the presentation of new clinical data from the STEM-PD Phase I/II clinical trial at the ISSCR 2026 Annual Meeting.

9 Jul 2026

Damaged myelin alters sleep brain rhythms in neurological diseases

Scientists have discovered how damage to the myelin sheath – the insulating layer around nerve fibres – affects brain activity during sleep.

9 Jul 2026

New study links overactive C1 neurons to prolonged anxiety responses

Anxiety disorders affect more than 300 million people globally. Several brain regions have been linked to anxiety, but how these regions connect has been poorly understood.

9 Jul 2026

Scientists discover molecular mechanism behind anesthesia-induced unconsciousness

Researchers at Weill Cornell Medicine and Birkbeck, University of London, have identified a site where a commonly used anesthetic binds to sodium ion channels, revealing a molecular mechanism that may explain how these drugs dampen communication between neurons.

9 Jul 2026