Prostate Specific Antigen News and Research

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Henry Ford surgeons use unique approach to perform first precision prostatectomy

Surgeons at Henry Ford Health System's Vattikuti Urology Institute performed what is believed to be the first precision prostatectomy through the bladder using a single port robotic surgical system.

13 Dec 2021

TP53 mutations in men may predispose to aggressive prostate cancer

Men who have mutations in a gene called TP53 have a high risk of developing aggressive prostate cancer, a multicenter research team in the United States has found.

11 Dec 2021

Men with inherited gene mutation have high risk of aggressive prostate cancer

Men who inherit mutations in a gene called TP53 have a high risk of developing aggressive prostate cancer, a multicenter research team in the United States has found.

2 Dec 2021

Regular blood tests can identify prostate cancer patients who are resistant to treatment

Regular blood tests before and during chemotherapy for prostate cancer can detect whether or not a patient is resistant or developing resistance to treatment with docetaxel, according to research presented at the NCRI Festival.

11 Nov 2021

Study highlights the increase in PSA screening for prostate cancer following revisions to USPSTF guidelines

In a large study led by Yale Cancer Center, more men received a prostate-specific antigen or PSA test to detect prostate cancer following revisions to the recommendation by the U.S. Preventative Services Task Force (USPSTF) on screening.

11 Nov 2021

Immune checkpoint protein may be a promising new target for prostate cancer immunotherapy

The immune checkpoint protein B7-H3 may be a promising new target for immunotherapy in treatment-resistant prostate cancers, according to two new studies led by researchers at the Johns Hopkins Kimmel Cancer Center.

2 Nov 2021

Fewer, higher doses of post-prostatectomy radiation therapy does not increase long-term side effects

Using fewer - but higher - doses of radiation to treat men with prostate cancer who had their prostates removed does not increase long-term side effects or lower their quality of life compared to conventional radiation treatment, a new, multi-institutional clinical trial shows.

25 Oct 2021

Studies address how plant-based diets impact men's health issues

Three new studies by University of Miami Miller School of Medicine urologists address how consuming healthy plant-based diets impact a range of men's health issues - from diabetes to sexual health.

24 Sep 2021

Tumor-related risk factors affect conversion of active surveillance to treatment for prostate cancer

For men with "low-risk" prostate cancer initially managed with active surveillance, cancer-related factors such as tumor grade and size are key risk factors for conversion to active treatment, reports a study in The Journal of Urology®, an Official Journal of the American Urological Association.

10 Sep 2021

Study provides new data on discontinuation of active surveillance by low-risk prostate cancer patients

Nearly half of men initially managed with active surveillance for "low-risk" prostate cancer transition to definitive treatment – such as surgery or radiation therapy – within a few years after diagnosis.

23 Aug 2021

Novel blood test as adjunct to MRI improves prostate cancer screening

Researchers at Karolinska Institutet in Sweden recently reported that magnetic resonance imaging (MRI) could reduce overdiagnoses and thereby improve prostate cancer screening.

12 Aug 2021

Genomic test may help identify prostate cancer patients at high risk of disease progression

After a biopsy comes back positive for prostate cancer, patients and their doctors are often left with a choice between taking a watch-and-wait approach, known as active surveillance, or proceeding with surgery or radiation.

27 Jul 2021

MRI screening and targeted biopsies could reduce overdiagnoses of prostate cancer

Most countries have not introduced nationwide prostate-cancer screening, as current methods result in overdiagnoses and excessive and unnecessary biopsies. A new study by researchers at Karolinska Institutet in Sweden, which is published in The New England Journal of Medicine, indicates that screening by magnetic resonance imaging (MRI) and targeted biopsies could potentially cut overdiagnoses by half.

9 Jul 2021

Gene variant in African Americans contributes to unnecessary bone marrow biopsies

A gene variant that lowers white blood cell levels and is common in individuals with African ancestry contributes to unnecessary bone marrow biopsies, according to a study published June 28 in JAMA Internal Medicine.

28 Jun 2021

Study explores the potential role of gene polymorphisms in pathogenesis of prostate cancer

Oncotarget published "The presence of polymorphisms in genes controlling neurotransmitter metabolism and disease prognosis in patients with prostate cancer: a possible link with schizophrenia" reported that polymorphisms of neurotransmitter metabolism genes were studied in patients with prostate cancer (PC) characterized by either reduced or extended serum prostate-specific antigen doubling time corresponding to unfavorable and favorable disease prognosis respectively.

28 Jun 2021

SWOG researchers to present practice-changing research at virtual ASCO 2021

"SWOG always brings an impressive portfolio of work to the ASCO annual meeting," said SWOG Chair Charles D. Blanke, MD, "and this year I'm particularly excited about the research our investigators are presenting because it includes results that are likely to be practice-changing."

1 Jun 2021

Medicare could save nearly $500 million per year by reducing use of low-value preventive care services

A UCLA-led study shows that physicians frequently order preventive medical services for adult Medicare beneficiaries that are considered unnecessary and of "low value" by the U.S. Preventive Services Task Force - at a cost of $478 million per year.

29 Apr 2021

City of Hope initiates Phase 2 clinical trial to investigate if mushroom tablets could slow prostate cancer

City of Hope, a world-renowned independent research and treatment center for cancer, diabetes and other life-threatening diseases, is now recruiting patients for a Phase 2 clinical trial to investigate whether pills containing white button mushroom extract could regulate the immune system, affecting prostate-specific antigen (PSA) levels to either remain stable or decline.

29 Apr 2021

New microfluidic system effectively isolates cancer spreading cells

The survival rate of cancer patients can drop to ten percent or less during metastasis, the spread of cancerous cells to create secondary tumors.

19 Apr 2021

Study may help develop effective biosensors for non-invasive diagnosis of prostate cancer

The efficacy of biosensors used in clinical tests depends critically on the surface of the device on which the biorecognition molecules are immobilized.

23 Mar 2021