Urethra News and Research

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In anatomy, the urethra is a tube which connects the urinary bladder to the outside of the body. The urethra has an excretory function in both genders to pass urine to the outside, and also a reproductive function in the male, as a passage for sperm.

Macrophages allow entry of HIV in the urethra

Having suggested in 2011 that the urethra is a novel entry site for HIV, a team from the Institut Cochin, has now confirmed this hypothesis and identified the cells and mechanisms brought into play: the immune system cells macrophages, present in the epithelium of the urethra, allow the entry of HIV. This work, published online on the website of the journal Mucosal Immunology, could make it possible to test novel HIV/AIDS prevention strategies.

1 Mar 2013

Surgery could boost chemotherapy outcomes in canine TCC

Dogs that undergo curative surgery for transitional cell carcinoma before initiating a combination of doxorubicin and piroxicam therapy have significantly longer median overall survival than their counterparts not pretreated surgically, report researchers.

6 Feb 2013

Study reports on development and testing of Hematuria Risk Index to predict cancer risk

Microscopic amounts of blood in urine have been considered a risk factor for urinary tract malignant tumors. However, only a small proportion of patients referred for investigation are subsequently found to have cancer. A new Kaiser Permanente Southern California study published in the February Mayo Clinic Proceedings reports on the development and testing of a Hematuria Risk Index to predict cancer risk.

10 Jan 2013

Novel device improves post-prostatectomy incontinence

Researchers have developed a novel device that improves stress urinary incontinence in men who have undergone prostatectomy, report researchers.

3 Dec 2012

Leading urologic oncologist explains bladder cancer basics

An unhappy bladder won't be ignored. Frequent urination, pain while urinating, burning while urinating, blood in the urine, and even back pain or pelvic pain can all be symptoms of bladder cancer or other urinary tract problems. The trick, however, is that the absence of urinary symptoms doesn't guarantee a healthy bladder.

27 Nov 2012

Janssen receives positive opinion from EMA CHMP for ZYTIGA to treat mCRPC

Janssen-Cilag International NV (Janssen) announced today that the Committee for Medical Products for Human Use (CHMP) of the European Medicines Agency (EMA) has granted a positive opinion recommending approval of the oral, once-daily medication ZYTIGA for use in combination with prednisone or prednisolone in the treatment of metastatic castration-resistant prostate cancer (mCRPC), in adult men who are asymptomatic or mildly symptomatic after failure of androgen deprivation therapy and in whom chemotherapy is not yet clinically indicated.

19 Nov 2012

High vitamin D levels associated with protection against bladder cancer

High levels of vitamin D are associated with protection against bladder cancer, according to a multidisciplinary study coordinated by molecular biologists and epidemiologists from the Spanish National Cancer Research Centre (CNIO), the conclusions of which are being published today in the Journal of National Cancer Institute (JNCI) .

31 Oct 2012

Study identifies multipotent and unipotent stem cells that contribute to prostate postnatal development

Publication in Nature Cell Biology advanced on line publication: researchers at the Université Libre de Bruxelles, ULB identify multipotent and unipotent Stem Cells (SCs) that contribute to prostate postnatal development.

16 Oct 2012

Lilly announces new data from two Phase II ramucirumab trials on NSCLC

Eli Lilly and Company today announced new data from two Phase II ramucirumab (IMC-1121B) trials in patients with non-small cell lung cancer (NSCLC).

1 Oct 2012

Many women undertreat pelvic floor disorders and suffer in silence

New research issued by the PFD Alliance finds that 90 percent of Americans underestimate or are unsure about the prevalence of pelvic floor disorders (PFDs) which will impact one in three women at some point during their lives. This means many women undertreat PFDs and suffer in silence.

19 Sep 2012

Surgery avoidable for some with persistent incontinence after prostatectomy

Researchers have identified factors that could help determine whether patients who have not recovered urinary continence more than 1 year after undergoing radical prostatectomy should undergo further surgery.

1 Aug 2012

Robot assists in complex uro surgery for pediatric patient

Pediatric specialists of Apollo Hospitals successfully completed a complex surgery on the bladder base of a 7 year old child from Africa with the assistance of a Robot. The child's urethra, the tube from the urinary bladder, was crushed in a road accident.

7 Jul 2012

Midurethral slings can prevent pre-operative urinary incontinence in women with vaginal prolapse

A multicenter study involving a UT Southwestern Medical Center urogynecologist will eliminate some of the guesswork physicians face about whether to use a sling during vaginal prolapse repair to prevent urinary incontinence.

21 Jun 2012

WHO calls for greater vigilance on correct use of antibiotics against gonorrhoea

Millions of people with gonorrhoea may be at risk of running out of treatment options unless urgent action is taken, according to WHO. Already several countries, including Australia, France, Japan, Norway, Sweden and the United Kingdom are reporting cases of resistance to cephalosporin antibiotics - the last treatment option against gonorrhoea. Every year an estimated 106 million people are infected with gonorrhea, which is transmitted sexually.

7 Jun 2012

Advaxis to update preliminary data on ADXS-HPV Phase 2 trial for cervical cancer

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, will update preliminary data on the safety and clinical benefit of ADXS-HPV from an ongoing randomized Phase 2 trial of ADXS-HPV with or without cisplatin in Indian women with recurrent/refractory cervical cancer who have failed cytotoxic therapy in a poster titled "ADXS11-001 immunotherapy targeting HPV-E7: Preliminary survival data from a phase II study in Indian women with recurrent/refractory cervical cancer" at the 2012 American Society of Clinical Oncology (ASCO) Annual Meeting held in Chicago, IL, on Sunday, June 3, 2012.

4 Jun 2012

Microbiome of young men depends upon circumcision status, patterns of sexual activity

The first study using cultivation independent sequencing of the microorganisms in the adolescent male urinary tract has revealed that the composition of microbial communities colonizing the penis in young men depends upon their circumcision status and patterns of sexual activity.

15 May 2012

Elusive G-spot does exist anatomically: New study

For centuries, women have been reporting engorgement of the upper, anterior part of the vagina during the stage of sexual excitement, despite the fact the structure of this phenomenon had not been anatomically determined.

25 Apr 2012

Study explains why some people develop kidney stones and others do not

Kidney stones strike an estimated 1 million Americans each year, and those who have experienced the excruciating pain say it is among the worst known to man (or woman).

19 Apr 2012

New embolization procedure may bring hope to men with enlarged prostate

A new interventional radiology treatment, prostatic artery embolization, may bring hope to men with debilitating symptoms caused by an enlarged prostate, say the group of researchers who pioneered its use.

26 Mar 2012

Clear link between androgenetic alopecia and benign prostate hyperplasia

Spanish scientists have confirmed that there is a clear relationship between androgenetic alopecia (common premature baldness) and benign prostate hyperplasia (BPH), a benign enlargement of the prostate that appears in aging men and is associated with certain hormones as dihydrotestosterone. This condition appears in 50% of men over 60 year old and causes voiding syndrome i.e. urinary frequency.

16 Mar 2012