Microscopy News and Research

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Cryogenic electron microscopy used to determine the structure of fungal ribosome

Most people carry the fungus Candida albicans on their bodies, without this causing many problems. However, a systemic infection with this fungus is dangerous and difficult to treat.

25 May 2022

New imaging approach helps scientists build a complete picture of brain networks

Researchers at the Francis Crick Institute have developed an imaging technique to capture information about the structure and function of brain tissue at subcellular level – a few billionth of a metre, while also capturing information about the surrounding environment.

25 May 2022

Researchers reveal novel tumor–macrophage interactions that promote peritoneal metastasis of ovarian cancer

A research team at the School of Biological Sciences, the University of Hong Kong, has revealed novel cellular and molecular interactions between cancer cells and tumor-associated macrophages that promote peritoneal metastasis of ovarian cancer.

25 May 2022

Study explores the substrate selectivity of the SARS-CoV-2 replicase

Researchers explored factors affecting substrate selection by the SARS-CoV-2 replicase.

24 May 2022

UAB researchers track the behavior of microplastics inside a living organism

A UAB research team has managed to track the behavior of microplastics during their "journey" through the intestinal tract of a living organism and illustrate what happens along the way.

23 May 2022

Novel AI algorithm developed for assessing digital pathology data

Digital pathology is an emerging field which deals with mainly microscopy images that are derived from patient biopsies.

23 May 2022

Study reports SARS-CoV-2 accessory proteins downregulate MHC-I expression using distinct mechanisms

Researchers observed SARS-CoV-2 downregulates the expression of MHC class I molecules.

23 May 2022

Deep visual proteomics is redefining cancer diagnostics

In a recent study published in the journal Nature Biotechnology, researchers introduced deep visual proteomics (DVP), an amalgamation of artificial intelligence (AI) for image analysis and mass spectrometry (MS) for proteomic profiling of biological samples.

22 May 2022

Researchers discover how one type of T cell creates functionally distinct, but genetically identical daughter cells

Scientists at St. Jude Children's Research Hospital have solved an immunology puzzle. A CD8+ T cell can have two functionally distinct daughter cells after it divides, despite the cells being genetically identical.

20 May 2022

Exploring the possibility of whether surface ACE2 carried by extracellular vesicles can facilitate SARS-CoV-2 infection

Researchers explored whether surface ACE2 carried by EVs can facilitate the entry of SARS-CoV-2 into host cells.

20 May 2022

Plastins may promote disease when they act like workaholics and disrupt cellular environment

A family of proteins that have a role in ensuring many types of cells move and maintain their shape may promote disease when they act like workaholics and disrupt the cellular environment, new research suggests.

19 May 2022

RNA binding-induced structural dynamics of SARS-CoV-2 nucleocapsid protein

Researchers predict structure models of the full-length SARS-CoV-2 N protein in both the presence and absence of RNA.

19 May 2022

Researchers combine two emerging imaging technologies to better view biomolecules

A research team from Carnegie Mellon University and Columbia have combined two emerging imaging technologies to better view a wide range of biomolecules, including proteins, lipids and DNA, at the nanoscale.

19 May 2022

Combined COVID-19 vaccination regimen found to induce more potent anti-SARS-CoV-2 antibodies

Researchers assessed the vaccine-induced humoral responses against SARS-CoV-2 post four different vaccination regimens comprising homologous and heterologous vaccine doses.

18 May 2022

Insight into sustained-release drug delivery systems

In this interview, News-Medical speaks to Thanh T. Nguyen, a project manager at Innocore Pharmaceuticals, about the mechanisms behind long-acting injectables.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 18 May 2022

Discovery of a potent SARS-CoV-2 RBD specific human monoclonal antibody

A recent article posted to the bioRxiv* preprint server demonstrated structural underpinnings of the neutralization of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variants by 002-S21F2, an extensive SARS-CoV-2 neutralizing antibody.

18 May 2022

Researchers develop treatment that suppresses mutational escape of SARS-CoV-2

Researchers from Xiamen University have created a new treatment that is less likely to be affected by mutations in the receptor-binding domain of SARS-CoV-2.

17 May 2022

Broad-spectrum polymeric antivirals against SARS-CoV-2

In a recent study published in the journal Advanced Science, researchers evaluated the potential and applicability of macromolecular viral inhibitors against respiratory viral pathogens.

17 May 2022

Why do diabetic patients have more severe SARS-CoV-2 infections?

A recent study published in the journal Cell Metabolism illustrated the function of angiotensin-converting enzyme 2 (ACE2) in renal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among diabetic patients.

16 May 2022

Targeting specific neurons modulates memory retrieval and alters anxiety-like behaviors in mice

We humans lose mental acuity, an unfortunate side effect of aging. And for individuals with neurodegenerative conditions such as Alzheimer's and Parkinson's, the loss of cognitive function often accompanied by mood disorders such as anxiety is a harrowing experience.

16 May 2022

Microscopy News and Research

Cryogenic electron microscopy used to determine the structure of fungal ribosome

New imaging approach helps scientists build a complete picture of brain networks

Researchers reveal novel tumor–macrophage interactions that promote peritoneal metastasis of ovarian cancer

Study explores the substrate selectivity of the SARS-CoV-2 replicase

UAB researchers track the behavior of microplastics inside a living organism

Novel AI algorithm developed for assessing digital pathology data

Study reports SARS-CoV-2 accessory proteins downregulate MHC-I expression using distinct mechanisms

Deep visual proteomics is redefining cancer diagnostics

Researchers discover how one type of T cell creates functionally distinct, but genetically identical daughter cells

Exploring the possibility of whether surface ACE2 carried by extracellular vesicles can facilitate SARS-CoV-2 infection

Plastins may promote disease when they act like workaholics and disrupt cellular environment

RNA binding-induced structural dynamics of SARS-CoV-2 nucleocapsid protein

Researchers combine two emerging imaging technologies to better view biomolecules

Combined COVID-19 vaccination regimen found to induce more potent anti-SARS-CoV-2 antibodies

Insight into sustained-release drug delivery systems

Discovery of a potent SARS-CoV-2 RBD specific human monoclonal antibody

Researchers develop treatment that suppresses mutational escape of SARS-CoV-2

Broad-spectrum polymeric antivirals against SARS-CoV-2

Why do diabetic patients have more severe SARS-CoV-2 infections?

Targeting specific neurons modulates memory retrieval and alters anxiety-like behaviors in mice

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