Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Researchers develop proof-of-concept nanosystem to enhance visualization of tumors

Researchers at Sanford Burnham Prebys Medical Discovery Institute have developed a proof-of-concept nanosystem that dramatically improves the visualization of tumors.

24 Aug 2017

Quanterix announces launch of new SR-Plex benchtop instrument for high sensitivity biomarker analysis

Quanterix Corporation, a company dedicated to digitizing biomarker analysis with the goal of advancing the science of precision health, today announced it will be expanding its single molecule array, or Simoa, technology platform portfolio to include the new Quanterix SR-Plex benchtop instrument.

23 Aug 2017

Id genes found to play crucial role in heart development

Researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), the Cardiovascular Institute at Stanford University and other institutions were surprised to discover that the four genes in the Id family play a crucial role in heart development, telling undifferentiated stem cells to form heart tubes and eventually muscle.

22 Aug 2017

Scientists reveal differences between human and murine microglia used in degenerative disease research

The results of a new research showed that many of the genes that are expressed by microglia are different between humans and mice, which are frequently used as animal models in research on Alzheimer's disease and other neurodegenerative disorders.

18 Aug 2017

Study shows feasibility of noninvasive retinal imaging for screening people at risk of AD

Alzheimer's disease (AD) represents the leading cause of dementia worldwide. Currently, challenges in making an early and definitive diagnosis of AD limit opportunities to intervene with disease-modifying therapies before substantial neurodegeneration occurs.

17 Aug 2017

Emory scientists use new tools to detect granulins for the first time inside cells

Emory University School of Medicine researchers have developed tools that enable them to detect small proteins called granulins for the first time inside cells.

14 Aug 2017

Brain scans reveal lower serotonin transporters in people with mild cognitive impairment

In a study looking at brain scans of people with mild loss of thought and memory ability, Johns Hopkins researchers report evidence of lower levels of the serotonin transporter -- a natural brain chemical that regulates mood, sleep and appetite.

14 Aug 2017

Counteracting premature aging

Aging is the continuing process of such stress exposures, and with advancing age (normal aging), we must carry lots of senescent cells within our bodies. Senescent cells also often provide some ‘bad influences’ to surrounding healthy cells; such as chronic inflammation and tumorigenesis

14 Aug 2017

Researchers develop set of tools to trace path of proteins linked to Parkinson's disease

As neurodegenerative disorders such as Parkinson's and Alzheimer's disease progress, misfolded proteins clump together in neurons, recruiting normal proteins in the cell to also misfold and aggregate.

4 Aug 2017

JAX receives new federal research grant to study mouse models of ALS

A new five-year federal research grant totaling $3,322,009 to The Jackson Laboratory (JAX) will fund studies of a new mouse model for amyotrophic lateral sclerosis (ALS).

4 Aug 2017

Study sheds new light on how anti-cancer agent inhibits tumor growth

Researchers at Sanford Burnham Prebys Medical Discovery Institute have published a study in Nature Communications shedding new light on how K-80003 (TX803), an anti-cancer agent discovered at the Institute, prevents activation of the PI3K pathway, resulting in inhibition of cancer cell growth.

4 Aug 2017

Study reveals biological basis of severe neurological disorder in children

In a new study published today in The American Journal of Human Genetics, a multinational team of researchers describes, for the first time, the biological basis of a severe neurological disorder in children.

3 Aug 2017

Scientists propose therapeutic strategy to suppress formation of hereditary bony tumors

Patients with multiple hereditary exostoses (MHE)--a rare disease that causes the growth of multiple benign bone tumors -- have limited treatment options.

3 Aug 2017

New analysis compares emerging algorithms that look for cancer mutations

Sanford Burnham Prebys Medical Discovery Institute has undertaken the first-ever comparative analysis of a newly emerging category of algorithms that mine genetic information in cancer databases by focusing on internal gene structure (subgene resolution algorithms), in contrast to classical approaches that focus on genes treated as single units.

17 Jul 2017

Inhibition of cell receptors clears toxic proteins, cuts inflammation and improves cognition in animal models

Researchers have found cell receptors abnormally overexpressed in post-mortem brains of those with Parkinson's and Alzheimer's diseases, and that they can be inhibited in animal models to clear toxic protein buildup, reduce brain inflammation, and improve cognitive performance.

17 Jul 2017

ASU-TGen researchers find source of altered ANK1 gene expression linked to Alzheimer's disease

Researchers led by Arizona State University and the Translational Genomics Research Institute have identified altered expression of a gene called ANK1, which only recently has been associated with memory robbing Alzheimer's disease, in specific cells in the brain.

14 Jul 2017

Neurodegeneration News and Research

Further Reading

Researchers develop proof-of-concept nanosystem to enhance visualization of tumors

Quanterix announces launch of new SR-Plex benchtop instrument for high sensitivity biomarker analysis

Id genes found to play crucial role in heart development

Scientists reveal differences between human and murine microglia used in degenerative disease research

Study shows feasibility of noninvasive retinal imaging for screening people at risk of AD

Emory scientists use new tools to detect granulins for the first time inside cells

Brain scans reveal lower serotonin transporters in people with mild cognitive impairment

Counteracting premature aging

Researchers develop set of tools to trace path of proteins linked to Parkinson's disease

JAX receives new federal research grant to study mouse models of ALS

Study sheds new light on how anti-cancer agent inhibits tumor growth

Study reveals biological basis of severe neurological disorder in children

Scientists propose therapeutic strategy to suppress formation of hereditary bony tumors

New analysis compares emerging algorithms that look for cancer mutations

Inhibition of cell receptors clears toxic proteins, cuts inflammation and improves cognition in animal models

ASU-TGen researchers find source of altered ANK1 gene expression linked to Alzheimer's disease

Researchers discover new role of enzyme in promoting self-destruction of axons

Scientists shed new light on how tau protein transitions from liquid state to solid tangles

Scientists provide detailed view of tau protein structures found in Alzheimer's disease

Dysfunctional microglia cells contribute to loss of synapses in Alzheimer's disease

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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