Laboratory News and Research

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Infants face high thrombosis risk

Russian scientists have carried out tests to compare the process of blood coagulation in adults and newborns and discovered that the latter face an increased risk of thrombosis.

1 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

A specific protein called TEAD1 is an important regulator of tumor migration in glioblastoma, the most common brain tumor in adults, and deactivating this protein may stop tumor cells from migrating away from the main tumor mass, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 1 in the journal Nature Communications.

1 Oct 2018

New analysis confirms value of minimal residual disease as prognostic indicator in multiple myeloma

Adaptive Biotechnologies today announced that Blood, the Journal of the American Society of Hematology, published online an analysis of patient samples from the Intergroupe Francophone du Myéloma 2009 trial.

1 Oct 2018

FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Today the U.S. Food and Drug Administration permitted marketing of ClonoSEQ assay, a next generation sequencing-based test for minimal residual disease in patients with acute lymphoblastic leukemiaor multiple myeloma. MRD is a measure of the amount of cancer cells remaining in a person's bone marrow.

30 Sep 2018

Promising vaccine may provide new treatment option for patients with HER2-positive cancers

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not previously been treated with a HER2-targeted therapeutic, according to data from a phase I clinical trial presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3.

30 Sep 2018

Asynt expands its range of DrySyn heating block systems for laboratories

Reflecting customer demand, Asynt have continued to expand their range of DrySyn heating block systems for reactions in tubes, vials and flasks.

From Asynt 29 Sep 2018

Adolescent marijuana users have used the drug in more than one form, research shows

Most teens who've tried marijuana have used the drug in more than one form, including cannabis products that are smoked, eaten or vaped, new USC research shows.

28 Sep 2018

Australian scientists resolve a key question in ovarian cancer care

Australian scientists have revealed a better way to identify which patients should respond to powerful ovarian cancer drugs called PARP inhibitors (PARPi), resolving an important question in ovarian cancer care about why some patients respond to these drugs, while others do not.

28 Sep 2018

Research reveals how critical oocyte quality control process works

Females are born with a finite number of eggs that are steadily depleted throughout their lifetime. This reserve of eggs is selected from a much larger pool of millions of precursor cells, or oocytes, that form during fetal life.

28 Sep 2018

Synthetic DNA vaccine targets proteins overexpressed in several types of cancer

Scientists at The Wistar Institute have implemented a novel structurally designed synthetic DNA vaccine to simultaneously target multiple members of a family of proteins that are specifically overexpressed in several types of cancer.

28 Sep 2018

Rochester and Minnesota team receives grant to create center for child maltreatment studies

The University of Rochester's Mt. Hope Family Center, in conjunction with the University of Minnesota's Institute for Translational Research in Children's Mental Health, has received a multi-million-dollar grant to create a national center for child maltreatment studies, becoming one of only three academic institutional partnerships in the United States to receive this prestigious award from the National Institutes of Health.

28 Sep 2018

CNL, TRIUMF team up to enable revolutionary cancer treatment

TRIUMF, Canada's particle accelerator center, and Canadian Nuclear Laboratories, Canada's premier nuclear science and technology organization, are pleased to announce that they have agreed to pursue a strategic partnership around the commercial production of Actinium-225, a rare medical isotope that has the potential to serve as the basis of new ground-breaking cancer treatments.

28 Sep 2018

Researchers develop new mathematical technique to study brain waves

A U.S. Army Research Laboratory scientist has collaborated with a team of researchers from the University of North Texas to develop a new data processing technique that uses electroencephalogram, or EEG, time series variability as a measure of the state of the brain.

27 Sep 2018

Henry Ford Hospital cardiologists are first in the U.S. to implant device for hard-to-treat angina

Cardiologists at Henry Ford Hospital performed the first implantation in the United States of a device approved for use in Europe for hard-to-treat angina.

27 Sep 2018

Fina Biosolutions receives patent for expression and purification of the conjugate vaccine protein

Fina Biosolutions announces that the United States Patent and Trademark Office has issued a patent for expression and purification of the conjugate vaccine protein CRM197 in E. coli.

27 Sep 2018

Crown Bioscience announces successful validation of well-characterized prostate cancer PDX models

Crown Bioscience, a global drug discovery and development services company providing translational platforms to advance oncology, inflammation, cardiovascular and metabolic disease research, has announced the addition of unique, well characterized, fully annotated patient-derived xenograft models of prostate cancer.

27 Sep 2018

CIRM approves $1.6M grant to help bring human islet-like organoids to diabetic patients

Approximately 1.25 million Americans are living with type 1 diabetes, with an additional 40,000 people newly diagnosed every year.

27 Sep 2018

Minicells play key function in self-preservation of bacteria, finds study

Scientists have known for decades that certain bacteria produce small spherical versions of themselves. Although they lack basic materials to reproduce or function like normal cells, recent interest in such "minicells" has spiked due to their proficiency as nano-sized delivery tools for drugs and vaccines to targeted cells and tissues.

27 Sep 2018

UC Riverside researchers receive NIH grant to study alcohol use disorders among Pacific Islanders

Pacific Islanders, who trace their roots to the native peoples of Hawaii, Guam, Samoa, and other Pacific Islands, make up the third-fastest-growing racial group in the United States.

27 Sep 2018

Laboratory News and Research

Infants face high thrombosis risk

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

New analysis confirms value of minimal residual disease as prognostic indicator in multiple myeloma

FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Promising vaccine may provide new treatment option for patients with HER2-positive cancers

Asynt expands its range of DrySyn heating block systems for laboratories

Adolescent marijuana users have used the drug in more than one form, research shows

Australian scientists resolve a key question in ovarian cancer care

Research reveals how critical oocyte quality control process works

Synthetic DNA vaccine targets proteins overexpressed in several types of cancer

Rochester and Minnesota team receives grant to create center for child maltreatment studies

CNL, TRIUMF team up to enable revolutionary cancer treatment

Researchers develop new mathematical technique to study brain waves

Henry Ford Hospital cardiologists are first in the U.S. to implant device for hard-to-treat angina

Fina Biosolutions receives patent for expression and purification of the conjugate vaccine protein

Crown Bioscience announces successful validation of well-characterized prostate cancer PDX models

CIRM approves $1.6M grant to help bring human islet-like organoids to diabetic patients

Minicells play key function in self-preservation of bacteria, finds study

UC Riverside researchers receive NIH grant to study alcohol use disorders among Pacific Islanders

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