Biochemistry News and Research

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New COVID-19 testing technology is a cheaper, faster alternative to tube-based RT-PCR tests

Throughout the COVID-19 pandemic, supply chain shortages of reagents and test kits have limited the rapid expansion of clinical testing needed to contain the virus.

18 May 2021

Researchers identify new compound that may prevent cardiac arrhythmia risk from common drugs

Dozens of commonly used drugs, including antibiotics, antinausea and anticancer medications, have a potential side effect of lengthening the electrical event that triggers contraction, creating an irregular heartbeat, or cardiac arrhythmia called acquired Long QT syndrome.

14 May 2021

New study may help develop senolytic drugs that target senescent immune cells

In a study recently published in Nature University of Minnesota Medical School researchers found that senescent immune cells are the most dangerous type of senescent cell.

13 May 2021

Study could help understand how Tuberous Sclerosis Complex arises

Tuberous Sclerosis Complex (TSC) affects between one and two of every 10,000 new-born babies. This genetic disease leads to the formation of benign tumors which can massively impair the proper functioning of vital organs such as the kidneys, the liver and the brain.

12 May 2021

New drug-like compound could effectively block a critical step in malaria parasite life cycle

Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop this compound into a potential first of its kind malaria treatment.

12 May 2021

GeroSense AI tracks biological age and resilience via smartphone sensor data

Gero has developed and validated GeroSense AI to track biological age and resilience via smartphone sensor data. The performance of the new health and aging markers have been recently reported in a paper in Aging US.

11 May 2021

Key protein helps bacteria that causes Legionnaires' disease to set up house in host cells

Scientists at UT Southwestern have discovered a key protein that helps the bacteria that causes Legionnaires' disease to set up house in the cells of humans and other hosts.

10 May 2021

Study: Bacterial colonization of infants' guts does not occur before birth

It is well known that each person's gut bacteria is vital for digestion and overall health, but when does that gut microbiome start?

10 May 2021

New "molecular tweezers" can help combat antibiotic-resistant bacteria

Researchers from Ben-Gurion University (BGU), together with American and German colleagues, have developed new "molecular tweezers" to combat antibiotic-resistant bacteria. Their recently announced findings were published in Cell Chemical Biology.

10 May 2021

UTMB researchers receive $11.3 million grant to study immunopathogenesis of Ebola

Researchers at the University of Texas Medical Branch at Galveston have been awarded an $11.3 Million, multi-year grant from the National Institute of Allergy and Infectious Diseases to study immunopathogenesis of Ebola, and in particular to determine why cells infected with Ebola develop "immune system paralysis," which inhibits immune response, leads to hyperinflammation, and allows the deadly infection to spread.

7 May 2021

Scientists investigate signal necrotic cells that cue phagocytic cells to engulf the dying cell

Just as people keep their houses clean and clutter under control, a crew of cells in the body is in charge of clearing the waste the body generates, including dying cells. The housekeeping cells remove unwanted material by a process called phagocytosis, which literally means 'eating cells.' The housekeepers engulf and ingest the dying cells and break them down to effectively eliminate them.

7 May 2021

Study investigates how Brd4 influences diet-induced obesity

A new study, published in JCI Insight, looks at how Brd4, a regulator of the innate immune response, influences diet-induced obesity.

4 May 2021

City of Hope initiates Phase 2 clinical trial to investigate if mushroom tablets could slow prostate cancer

City of Hope, a world-renowned independent research and treatment center for cancer, diabetes and other life-threatening diseases, is now recruiting patients for a Phase 2 clinical trial to investigate whether pills containing white button mushroom extract could regulate the immune system, affecting prostate-specific antigen (PSA) levels to either remain stable or decline.

29 Apr 2021

New genetically encoded sensor helps detect drugs of abuse

A genetically encoded sensor to detect hallucinogenic compounds has been developed by researchers at the University of California, Davis. Named psychLight, the sensor could be used in discovering new treatments for mental illness, in neuroscience research and to detect drugs of abuse. The work is published April 28 in the journal Cell.

29 Apr 2021

Texas A&M AgriLife receives grant to support research on bacteriophage therapy

The National Institute of Allergy and Infectious Diseases, NIAID, part of the National Institutes of Health, NIH, has awarded $2.5 million in grants to support research on bacteriophage therapy, and Texas A&M AgriLife Research is among the grant recipients.

29 Apr 2021

Nanobodies may be the key to blocking tick-borne bacterial infection

Tiny molecules called nanobodies, which can be designed to mimic antibody structures and functions, may be the key to blocking a tick-borne bacterial infection that remains out of reach of almost all antibiotics, new research suggests.

28 Apr 2021

Researchers identify potential therapeutic target to prevent neurodegeneration after a stroke

Researchers with the Peter O'Donnell Jr. Brain Institute at UT Southwestern have identified a new protein implicated in cell death that provides a potential therapeutic target that could prevent or delay the progress of neurodegenerative diseases following a stroke.

27 Apr 2021

Study offers insight into how damage to airways of the lung develops into pre-cancer lesions

Lung carcinomas are the leading cause of cancer-related deaths in the United States and worldwide. Lung squamous cell carcinomas (non-small cell lung cancers that arise in the bronchi of the lungs and make up approximately 30 percent of all lung cancers) are poorly understood, particularly with respect to the cell type and signals that contribute to disease onset.

26 Apr 2021

Football Fitness improves balance, muscle strength and bone density in women treated for breast cancer

The University of Southern Denmark, Rigshospitalet and the University of Copenhagen have come together to study the effects of Football Fitness on various health parameters and self-rated health following treatment for breast cancer.

26 Apr 2021

The potential of CRISPR-based diagnostic assays and treatment approaches against COVID-19

In their review paper recently published in the Indian Journal of Clinical Biochemistry, a group of authors discusses currently available and forthcoming CRISPR-based diagnostic assays, as well as the possibility of using the CRISPR/Cas system as a salient treatment or prevention strategy in the fight against coronavirus disease 2019 (COVID-19).

25 Apr 2021

Biochemistry News and Research

New COVID-19 testing technology is a cheaper, faster alternative to tube-based RT-PCR tests

Researchers identify new compound that may prevent cardiac arrhythmia risk from common drugs

New study may help develop senolytic drugs that target senescent immune cells

Study could help understand how Tuberous Sclerosis Complex arises

New drug-like compound could effectively block a critical step in malaria parasite life cycle

GeroSense AI tracks biological age and resilience via smartphone sensor data

Key protein helps bacteria that causes Legionnaires' disease to set up house in host cells

Study: Bacterial colonization of infants' guts does not occur before birth

New "molecular tweezers" can help combat antibiotic-resistant bacteria

UTMB researchers receive $11.3 million grant to study immunopathogenesis of Ebola

Scientists investigate signal necrotic cells that cue phagocytic cells to engulf the dying cell

Study investigates how Brd4 influences diet-induced obesity

City of Hope initiates Phase 2 clinical trial to investigate if mushroom tablets could slow prostate cancer

New genetically encoded sensor helps detect drugs of abuse

Texas A&M AgriLife receives grant to support research on bacteriophage therapy

Nanobodies may be the key to blocking tick-borne bacterial infection

Researchers identify potential therapeutic target to prevent neurodegeneration after a stroke

Study offers insight into how damage to airways of the lung develops into pre-cancer lesions

Football Fitness improves balance, muscle strength and bone density in women treated for breast cancer

The potential of CRISPR-based diagnostic assays and treatment approaches against COVID-19

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