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Different statin drugs exert different effects on COVID-19 patients

We've all recently gotten a crash-course in drug repurposing, thanks to near-daily news reports about efforts to identify existing medicines that could help treat COVID-19 in the early phase of the pandemic.

9 May 2023

Anticoronavirals: the development of COVID-19 therapies and the challenges that remain

Researchers highlighted the pace of development of COVID-19 therapies during the pandemic and the challenges that hinder the widespread availability of anticoronavirals.

8 May 2023

First CRISPR-armed phage therapeutic can specifically target and remove E. coli in the human gut

SNIPR Biome ApS ("SNIPR"), the company pioneering CRISPR-based microbial gene therapy, announces today that Nature Biotechnology has published research findings from its preclinical work on SNIPR001, the first CRISPR-armed phage therapeutic developed to specifically target and remove E. coli, including antibiotic-resistant strains, in the human gastrointestinal tract.

8 May 2023

Evaluating the effectiveness of both BA.1-containing and BA.4/BA.5-containing bivalent COVID-19 mRNA vaccines

Researchers evaluated the effectiveness, in absolute and relative terms, of vaccines.

5 May 2023

Unlocking the puzzle: How ACE2 shapes macrophage responses in COVID-19

A new study investigates whether SARS-CoV-2 can enter and replicate in macrophages and whether ACE2 is involved in these mechanisms.

4 May 2023

The effects of vitamin C, vitamin E, and β-carotene on the gut microbiota

Researchers reviewed the impact of vitamins C and E and β-carotene on the gut microbiome to understand how known vitamins modify the gut microbiota.

4 May 2023

Revving up COVID mRNA vaccines: Algorithm generates 128-fold increase in antibodies

Research paper proposes a new method for predicting highly expressed genes based on codon usage bias and minimum free energy of mRNA secondary structures. The method involves constructing a stochastic grammar that generates sequences with high CAI and low MFE, and testing it on two mRNA vaccines.

3 May 2023

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

In a recent study published in the journal Cell Stem Cell, researchers hypothesized that pacemaker-like activity of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) resulted in engraftment arrhythmias (EAs), which hampers the clinical use of cell-based therapy using hPSC-CMs for treatment of myocardial infarction (MI).

2 May 2023

Montana considers requiring insurance to cover fertility preservation for cancer patients

Katie Beall was diagnosed with breast cancer on March 1, 2022. Two days later, doctors told her the chemotherapy she needed would make her infertile.

28 Apr 2023

A study surveilling Vermont wildlife detects no SARS-CoV-2

The surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in wildlife in Vermont, United States (US).

28 Apr 2023

Does carrot-derived rhamnogalacturonan I positively impact gut microbiota composition and function?

Researchers assessed how carrot-derived rhamnogalacturonan I (cRG-I) impacted the human gut microbiota.

28 Apr 2023

Developing Next-Generation Nanomaterials for Medical Applications

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to Dr. Chad Merkin, Director of the International Institute for Nanotechnology, about his work developing next-generation nanomaterials for medical applications.

From Pittcon 27 Apr 2023

Neurological phenotypes induced by SARS-CoV-2 spike protein in neurons

Researchers explored the association between SARS-CoV-2 spike protein and burst activities in neurons.

27 Apr 2023

Study reveals the mechanism behind oligomeric assembly of a BAR-domain-containing protein

Cell membranes play a critical role by serving as containment units and separating the inner cellular space from the extracellular environment.

26 Apr 2023

Print your own vaccine: automatic printing of microneedle patch COVID-19 mRNA vaccines

Researchers reported on the automatic printing of microneedle patch SARS-CoV-2 mRNA vaccines.

26 Apr 2023

Shedding light on diabetes: Vitamin D's crucial role in insulin regulation and disease prevention

Research discusses the role of vitamin D in both type 1 and type 2 diabetes pathogenesis. It summarizes the molecular mechanisms of vitamin D in insulin secretion, insulin sensitivity, and immunity, as well as the observational and interventional human studies investigating the use of vitamin D as a treatment for diabetes.

25 Apr 2023

Study establishes a new method for examining relationships between neuron type and function

Investigators at Cedars-Sinai have created computer-generated models to bridge the gap between "test tube" data about neurons and the function of those cells in the living brain.

25 Apr 2023

Is there an association between the consumption of ultra-processed food and adverse microbiota-gut-brain axis implications?

Researchers reviewed the impact of ultra-processed foods (UPFs) on the microbiota-gut-brain axis.

25 Apr 2023

Does oral exposure to cannabidiol (CBD) have toxic implications?

Researchers reviewed the implications of oral exposure to cannabidiol (CBD).

25 Apr 2023

Understanding how consumption of beef vs. plant-based burgers alters the lipemic response and gut microbiota

Researchers reviewed the differences in the digestive process between beef and plant-based burgers from ingestion to excretion.

25 Apr 2023

in vitro News and Research

Different statin drugs exert different effects on COVID-19 patients

Anticoronavirals: the development of COVID-19 therapies and the challenges that remain

First CRISPR-armed phage therapeutic can specifically target and remove E. coli in the human gut

Evaluating the effectiveness of both BA.1-containing and BA.4/BA.5-containing bivalent COVID-19 mRNA vaccines

Unlocking the puzzle: How ACE2 shapes macrophage responses in COVID-19

The effects of vitamin C, vitamin E, and β-carotene on the gut microbiota

Revving up COVID mRNA vaccines: Algorithm generates 128-fold increase in antibodies

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

Montana considers requiring insurance to cover fertility preservation for cancer patients

A study surveilling Vermont wildlife detects no SARS-CoV-2

Does carrot-derived rhamnogalacturonan I positively impact gut microbiota composition and function?

Developing Next-Generation Nanomaterials for Medical Applications

Neurological phenotypes induced by SARS-CoV-2 spike protein in neurons

Study reveals the mechanism behind oligomeric assembly of a BAR-domain-containing protein

Print your own vaccine: automatic printing of microneedle patch COVID-19 mRNA vaccines

Shedding light on diabetes: Vitamin D's crucial role in insulin regulation and disease prevention

Study establishes a new method for examining relationships between neuron type and function

Is there an association between the consumption of ultra-processed food and adverse microbiota-gut-brain axis implications?

Does oral exposure to cannabidiol (CBD) have toxic implications?

Understanding how consumption of beef vs. plant-based burgers alters the lipemic response and gut microbiota

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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