Genes News and Research

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Molecular signaling pathway could be basis of potential new treatment for osteoporosis

A molecular signaling pathway identified by an international research team could be the basis of improved treatment for osteoporosis.

19 Oct 2016

IBM, Quest Diagnostics launch new genomic tumor sequencing service to help advance precision medicine

IBM Watson Health and Quest Diagnostics today announced the launch of IBM Watson Genomics from Quest Diagnostics, a new service that helps advance precision medicine by combining cognitive computing with genomic tumor sequencing.

From Quest Diagnostics 19 Oct 2016

Biomedical engineers harvest bacterial genes that can improve electrical signaling in human cells

Duke University biomedical engineers have harvested genes for ion channels from bacteria that, with a few tweaks, can create and enhance electrical signaling in human cells, making the cells more electrically excitable.

19 Oct 2016

Mouths of migraine sufferers harbor more nitrate-reducing bacteria, study finds

Researchers at University of California San Diego School of Medicine have found that the mouths of migraine sufferers harbor significantly more microbes with the ability to modify nitrates than people who do not get migraine headaches.

19 Oct 2016

Folinic acid treatment could help improve language and communication skills of children with ASD

Prescription doses of folinic acid, which is a reduced form of a B vitamin known as folate, could help improve the language and communication skills of children with autism spectrum disorder (ASD).

18 Oct 2016

BUSM researcher receives nearly $20 million grant to support dementia and AD research

Sudha Seshadri, MD, professor of neurology at Boston University School of Medicine, has been awarded three grants this year totaling nearly $20 million from the National Institute on Aging and the National Institute of Neurological Disorders and Stroke.

18 Oct 2016

Chemotherapy leads to drug-resistance in bladder cancer patients

Chemotherapy is indicated as the first line of treatment for advanced bladder cancer. New research by Weill Cornell Medicine and University of Trento scientists shows that while chemotherapy kills the most common type of bladder cancer, urothelial cancer, chemotherapy also shapes the genetic evolution of remaining urothelial cancer cell clones to become drug-resistant.

18 Oct 2016

Anti-inflammatory drugs may improve severity of depressive symptoms, study finds

Anti-inflammatory drugs similar to those used to treat conditions such as rheumatoid arthritis and psoriasis could in future be used to treat some cases of depression, concludes a review led by the University of Cambridge, which further implicates our immune system in mental health disorders.

18 Oct 2016

Sleep abnormality may play vital role in schizophrenia, say BIDMC experts

A sleep abnormality likely plays an important role in schizophrenia, according to sleep experts at Beth Israel Deaconess Medical Center.

18 Oct 2016

Cold medication could suppress spread of bladder cancers

Hokkaido University researchers have discovered that a nonsteroid anti-inflammatory drug used for treating colds suppresses the spread of bladder cancers and reduces their chemoresistance in mice, raising hopes of a future cure for advanced bladder cancers.

17 Oct 2016

Penn researchers identify new immune system mechanism to fight against infections

The innate immune system serves as a first-line defense, responding to infections almost immediately after a pathogen makes its way into the body.

17 Oct 2016

Icelandic people more likely to carry novel rare genetic variant linked to risk of Alzheimer's disease

People with Icelandic heritage are more likely to carry a novel rare mutation in the TM2D3 gene, which leads to greater risk for Alzheimer's disease, based on a new study published October 14th, 2016 in PLOS Genetics by Johanna Jakobsdottir of the Icelandic Heart Association, Sven van der Lee of Erasmus University in Rotterdam, and colleagues.

17 Oct 2016

Scientists develop software package to predict chemical properties of molecules

Scientists from MIPT's Research Center for Molecular Mechanisms of Aging and Age-Related Diseases together with Inria research center, Grenoble, France have developed a software package called Knodle to determine an atom's hybridization, bond orders and functional groups' annotation in molecules.

17 Oct 2016

Immune system plays important role in Duchenne muscular dystrophy, research reveals

A new paper, co-written by faculty at Binghamton University, State University of New York, increases the understanding of Duchenne muscular dystrophy (DMD)—one of the most common lethal genetic disorders—and points to potential therapeutic approaches.

14 Oct 2016

Cleveland Clinic cancer researchers receive $2.4 million grant from NIH NHLBI

The National Institutes of Health National Heart, Lung and Blood Institute has awarded a $2.4 million grant over four years to Cleveland Clinic cancer researchers Jaroslaw Maciejewski, M.D., and Richard Padgett, Ph.D., to test the hypothesis that alterations in the pattern of splicing of target genes play a major role in the establishment or progression of myelodysplastic syndromes (MDS).

14 Oct 2016

Swedish researchers develop new, low-cost method to examine individual leukemia cells

Leukemia is a disease in which each cell can exhibit different genetic traits, and now Swedish researchers have found a cheap way to examine the individual cells. Reported in Nature Communications, the breakthrough could transform leukemia treatment.

14 Oct 2016

Crohn's disease appears to have two distinct genetic subtypes, study finds

Crohn's disease, a common inflammatory disorder of the intestinal tract, can have devastating consequences for a patient's quality of life and is notoriously hard to treat successfully, in part because its course and severity vary so much from one case to the next.

14 Oct 2016

Substance NAD+ can extend life and postpone onset of aging processes

The coenzyme NAD+ plays a main role in aging processes. In mice and roundworm adding the substance can both extend life and postpone the onset of aging processes.

14 Oct 2016

Researchers develop mouse model to investigate behavioral effects of eating disorder gene

Giving mice a gene mutation linked to eating disorders in people causes feeding and behavior abnormalities similar to symptoms often seen in patients with eating disorders. Only female mice are affected by the gene mutation, and some of the abnormalities in the female mice depend on whether they are housed alone or together with other mice.

13 Oct 2016

Depriving deadly brain cancer cells of cholesterol causes tumor regression in mouse models

Researchers at University of California San Diego School of Medicine, Ludwig Institute for Cancer Research and The Scripps Research Institute, with colleagues in Los Angeles and Japan, report that depriving deadly brain cancer cells of cholesterol, which they import from neighboring healthy cells, specifically kills tumor cells and caused tumor regression and prolonged survival in mouse models.

13 Oct 2016

Genes News and Research

Molecular signaling pathway could be basis of potential new treatment for osteoporosis

IBM, Quest Diagnostics launch new genomic tumor sequencing service to help advance precision medicine

Biomedical engineers harvest bacterial genes that can improve electrical signaling in human cells

Mouths of migraine sufferers harbor more nitrate-reducing bacteria, study finds

Folinic acid treatment could help improve language and communication skills of children with ASD

BUSM researcher receives nearly $20 million grant to support dementia and AD research

Chemotherapy leads to drug-resistance in bladder cancer patients

Anti-inflammatory drugs may improve severity of depressive symptoms, study finds

Sleep abnormality may play vital role in schizophrenia, say BIDMC experts

Cold medication could suppress spread of bladder cancers

Penn researchers identify new immune system mechanism to fight against infections

Icelandic people more likely to carry novel rare genetic variant linked to risk of Alzheimer's disease

Scientists develop software package to predict chemical properties of molecules

Immune system plays important role in Duchenne muscular dystrophy, research reveals

Cleveland Clinic cancer researchers receive $2.4 million grant from NIH NHLBI

Swedish researchers develop new, low-cost method to examine individual leukemia cells

Crohn's disease appears to have two distinct genetic subtypes, study finds

Substance NAD+ can extend life and postpone onset of aging processes

Researchers develop mouse model to investigate behavioral effects of eating disorder gene

Depriving deadly brain cancer cells of cholesterol causes tumor regression in mouse models

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