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Free SARS-CoV-2 spike protein fragments may trigger platelet activation and clot formation in COVID-19

In a recent study under review in the Nature Portfolio journal and currently available on the Research Square* preprint server, researchers investigated the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (SP) in the thrombi (or blood clots).

5 May 2022

New study helps explain the immune system’s response to skin infections and skin cancers

It is well established that older adults are more susceptible to infection and their immune systems less capable of generating a strong immune response.

4 May 2022

Hypertonic saline solution enhances glymphatic spinal cord delivery of pharmaceutical agents

The glymphatic system enables the flow of cerebrospinal fluid to the brain tissue, particularly during sleep, enabling the fluid to cleanse the tissue and carry accumulated metabolites with it towards the bloodstream during waking hours.

4 May 2022

Study evaluates the associations between predisposing risk factors and heart attack in young women

A new Yale-led study has for the first time identified which risk factors are more likely to trigger a heart attack or acute myocardial infarction (AMI) for men and women 55 years and younger.

4 May 2022

People with highest levels of antioxidants less likely to develop dementia, finds study

People with higher levels of antioxidants in their blood may be less likely to develop dementia, according to a study published in the May 4, 2022, online issue of Neurology, the medical journal of the American Academy of Neurology.

4 May 2022

Evaluating a third SARS-CoV-2 mRNA vaccine in anti-CD20-treated patients

In a new study, researchers assessed the efficacy of a third dose of COVID-19 vaccine in anti-CD20 antibody-treated individuals.

4 May 2022

Phase 2 clinical trial of COVID-19 convalescent plasma with high antibody titers

Researchers determined the threshold neutralizing antibody titer for effective COVID-19 convalescent plasma therapy.

4 May 2022

Evaluating immune protection after third and fourth doses of homologous and heterologous SARS-CoV-2 vaccines among kidney transplant recipients

Researchers evaluated the immune responses after the third and fourth doses of homologous and heterologous mRNA vaccines against COVID-19 in kidney transplant recipients.

4 May 2022

Effect of vegetarian food intake on nutritional status and growth of young children

In a new study, researchers examined the association between a vegetarian diet and growth, micronutrients, and lipids among healthy children.

4 May 2022

High-performing age-stratified machine-learning models for the prediction of the severity of COVID-19 progression

The current study aims to use sophisticated machine learning models that stratify patient data by age group to predict disease progression in almost 7,000 patients studied in community hospital settings.

4 May 2022

Endocrine-disrupting chemicals may be linked with lower bone mineral density in male teens

Per- and polyfluoroalkyl substances (PFAS) and phthalates (two types of endocrine-disrupting chemicals) may be associated with lower bone mineral density in male teens, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism.

4 May 2022

New drug combinations for obesity and diabetes may show greater efficacy than single therapy

Canadian and German researchers are teaming up to identify new drug combinations to treat people with obesity and Type 2 diabetes.

4 May 2022

Researchers reveal the mechanism of action of century-old BCG vaccine

The century-old Bacille Calmette-Guérin (BCG) vaccine against tuberculosis is one of the world's oldest and most widely used vaccines, used to immunize 100 million newborns every year. Given in countries with endemic TB, it has surprisingly been found to protect newborns and young infants against multiple bacterial and viral infections unrelated to TB. There's even some evidence that it can reduce severity of COVID-19.

4 May 2022

Two specific brain networks can strongly influence weight-loss success

When it comes to weight loss, the old adage it's all in your head may be true.

4 May 2022

Reducing daily sedentary time can help prevent diabetes and cardiovascular diseases

A new study suggests that reducing daily sedentary time can have a positive effect on the risk factors of lifestyle diseases already in three months. Spending just one hour less sitting daily and increasing light physical activity can help in the prevention of these diseases.

4 May 2022

Elevated levels of PHGDH enzyme associated with Alzheimer’s disease pathology

Elevated levels of an enzyme called PHGDH in the blood of older adults could be an early warning sign of Alzheimer's disease, and a study led by the University of California San Diego provides new evidence to support this claim.

4 May 2022

Scientists discover a potential new method of active immunization to prevent Alzheimer's disease

During experiments in animal models, researchers at the University of Kansas have discovered a possible new approach to immunization against Alzheimer's disease (AD).

4 May 2022

Study reveals trends in clinical characteristics and outcomes of STEMI patients with COVID-19

A newly published analysis in the Journal of the American College of Cardiology1 of hospitalized patients with both a severe type of heart attack called STEMI (ST-elevation myocardial infarction) and coronavirus disease-19 (COVID-19) infection compares clinical outcomes for these patients during the first and second years of the COVID-19 pandemic.

3 May 2022

Pets living in households with COVID-19 are high likely to seroconvert and become ill

In a recent study published in the journal Emerging Infectious Diseases, researchers investigated whether pet dogs and cats in the households of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected humans were at risk of infection.

3 May 2022

UNC researcher working with NASA to study blood clot formation in astronauts during space missions

Are astronauts more likely to develop blood clots during space missions due to zero gravity? That's the question NASA is trying to answer with help from UNC School of Medicine's Stephan Moll, MD, professor in the UNC Department of Medicine.

3 May 2022

Blood News and Research

Free SARS-CoV-2 spike protein fragments may trigger platelet activation and clot formation in COVID-19

New study helps explain the immune system’s response to skin infections and skin cancers

Hypertonic saline solution enhances glymphatic spinal cord delivery of pharmaceutical agents

Study evaluates the associations between predisposing risk factors and heart attack in young women

People with highest levels of antioxidants less likely to develop dementia, finds study

Evaluating a third SARS-CoV-2 mRNA vaccine in anti-CD20-treated patients

Phase 2 clinical trial of COVID-19 convalescent plasma with high antibody titers

Evaluating immune protection after third and fourth doses of homologous and heterologous SARS-CoV-2 vaccines among kidney transplant recipients

Effect of vegetarian food intake on nutritional status and growth of young children

High-performing age-stratified machine-learning models for the prediction of the severity of COVID-19 progression

Endocrine-disrupting chemicals may be linked with lower bone mineral density in male teens

New drug combinations for obesity and diabetes may show greater efficacy than single therapy

Researchers reveal the mechanism of action of century-old BCG vaccine

Two specific brain networks can strongly influence weight-loss success

Reducing daily sedentary time can help prevent diabetes and cardiovascular diseases

Elevated levels of PHGDH enzyme associated with Alzheimer’s disease pathology

Scientists discover a potential new method of active immunization to prevent Alzheimer's disease

Study reveals trends in clinical characteristics and outcomes of STEMI patients with COVID-19

Pets living in households with COVID-19 are high likely to seroconvert and become ill

UNC researcher working with NASA to study blood clot formation in astronauts during space missions

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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