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SARS-CoV-2 hijacks tiny bridges that link infected cells with neurons to gain access to brain cells

COVID-19 often leads to neurological symptoms, such as a loss of taste or smell, or cognitive impairments (including memory loss and concentration difficulties), both during the acute phase of the disease and over the long term with "long COVID" syndrome.

25 Jul 2022

Researchers investigate the feasibility of modifying cholera toxin for targeted delivery to specific organelles

Proteins usually undergo modifications during or after their synthesis in the endoplasmic reticulum (ER) and Golgi apparatus network inside eukaryotic cells.

25 Jul 2022

SARS-CoV-2 spike protein can lead to heart muscle injury through the inflammatory process

Heart damage is common among patients hospitalized with COVID-19, leading many to wonder how the virus affects the heart.

25 Jul 2022

Study provides the crucial antigenic map of SARS-CoV-2 variants of concern

Twenty different COVID-19 variants were effectively identified and neutralized after a third booster, according to the new study for which the University of Surrey provided the crucial antigenic map of variants of concern.

25 Jul 2022

Study suggests a possible treatment approach for cancer and cardiovascular disease

A key molecule for cancer metastasis has been identified as a molecule already known for its involvement in cardiovascular disease, suggesting a possible treatment approach for both diseases simultaneously.

25 Jul 2022

Study identifies risks in the use of CRISPR therapeutics

The researchers caution: "The CRISPR genome editing method is very effective, but not always safe. Sometimes cleaved chromosomes do not recover and genomic stability is compromised - which in the long run might promote cancer."

25 Jul 2022

Research reveals molecular clues associated with traumatic brain injury

New research led by scientists at Arizona State University has revealed some of the first detailed molecular clues associated with one of the leading causes of death and disability, a condition known as traumatic brain injury (TBI).

23 Jul 2022

Defect in a protein causes motor disorders in flies

Researchers at the Universities of Bonn and Osnabrück have discovered a protein whose defect causes motor disorders in flies.

22 Jul 2022

Two UTHSC research teams receive CORNET Awards for novel projects

Two research teams at the University of Tennessee Health Science Center (UTHSC) have been awarded the 2022 UTHSC Collaborative Research Network (CORNET)-Functional Genomics Award. Each team will receive $50,000 to support their novel projects.

22 Jul 2022

Study reveals new mechanism that regulates auditory sensitivity

A new study published in PNAS highlights a newly identified mechanism of how auditory sensitivity is regulated that could temporarily reduce sensitivity of the auditory system to protect itself from loud sounds that can cause irreversible damage.

22 Jul 2022

Lymphatic capillaries act as a signaling hub to control intestinal stem cell activity

To act as a robust barrier against pathogens while also absorbing needed nutrients, the lining of the intestines must regenerate on a daily basis to remain equal to the task.

22 Jul 2022

Study clarifies the role of intestinal white blood cells in colorectal cancer

Colorectal tumors are swarming with white blood cells, but whether these cells help or hinder the cancer is hotly debated.

22 Jul 2022

UTHSC investigators secure $2.16 million to test a new way to combat neurodegenerative disorders

The National Institute on Aging recently awarded $2.16 million to a team of investigators from the University of Tennessee Health Science Center (UTHSC) testing a new way to combat the root cause of neurodegenerative disorders such as Alzheimer's Disease.

22 Jul 2022

Maternal antibodies may play a key role in protecting infants from congenital HCMV infections

Antibodies that summon virus-engulfing white blood cells may play an important role in protecting infants from potentially serious congenital infection with human cytomegalovirus (HCMV), according to a study led by an investigator at Weill Cornell Medicine and NewYork-Presbyterian.

22 Jul 2022

NIH grant awarded to Marshall researcher for studying genetic mechanisms of cocaine addiction

Price E. Dickson, Ph.D., an assistant professor of biomedical sciences at the Marshall University Joan C. Edwards School of Medicine, has received a $407,000 grant from the National Institutes of Health to study the genetic and genomic mechanisms driving the relationship between social reward and cocaine addiction.

22 Jul 2022

Improving the immune defenses against blood cancer

For patients with lymphoma, multiple myeloma, or certain types of leukemia, treatment with chimeric antigen receptor T cells (CAR T cells) is sometimes the last chance of overcoming the cancer.

22 Jul 2022

Researchers discover a ‘weak spot’ that makes multi-drug resistant tumors vulnerable

One of the greatest challenges facing cancer researchers is to understand why some patients don't respond to treatments.

22 Jul 2022

New biomimetic formulation developed to tackle glioblastoma multiforme

Glioblastoma multiforme (GBM) is an aggressive brain cancer with a poor prognosis and few treatment options. New and effective approaches for GBM treatment are therefore urgently needed.

22 Jul 2022

Antibodies' neutralization efficacy against Omicron variants BA.1 And BA.2 wanes rapidly, study finds

The Omicron variant of the SARS-CoV-2 virus was first detected in South Africa in November 2021. The high level of infectiousness of the virus and its ability to quickly spawn additional variants has also been observed in Germany: Since January 2022 the Omicron variant BA.1 has dominated here, followed in subsequent months by the variant BA.2.

22 Jul 2022

Study examines the maintenance of immunity to SARS-CoV-2 after natural infection or post-vaccination

A new study examined the maintenance of memory B cell responses to SARS-CoV-2, the virus that causes COVID-19, after recovery from natural infection or post-vaccination.

22 Jul 2022

Cell News and Research

SARS-CoV-2 hijacks tiny bridges that link infected cells with neurons to gain access to brain cells

Researchers investigate the feasibility of modifying cholera toxin for targeted delivery to specific organelles

SARS-CoV-2 spike protein can lead to heart muscle injury through the inflammatory process

Study provides the crucial antigenic map of SARS-CoV-2 variants of concern

Study suggests a possible treatment approach for cancer and cardiovascular disease

Study identifies risks in the use of CRISPR therapeutics

Research reveals molecular clues associated with traumatic brain injury

Defect in a protein causes motor disorders in flies

Two UTHSC research teams receive CORNET Awards for novel projects

Study reveals new mechanism that regulates auditory sensitivity

Lymphatic capillaries act as a signaling hub to control intestinal stem cell activity

Study clarifies the role of intestinal white blood cells in colorectal cancer

UTHSC investigators secure $2.16 million to test a new way to combat neurodegenerative disorders

Maternal antibodies may play a key role in protecting infants from congenital HCMV infections

NIH grant awarded to Marshall researcher for studying genetic mechanisms of cocaine addiction

Improving the immune defenses against blood cancer

Researchers discover a ‘weak spot’ that makes multi-drug resistant tumors vulnerable

New biomimetic formulation developed to tackle glioblastoma multiforme

Antibodies' neutralization efficacy against Omicron variants BA.1 And BA.2 wanes rapidly, study finds

Study examines the maintenance of immunity to SARS-CoV-2 after natural infection or post-vaccination

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