Genes News and Research

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Immunotherapy already in clinical trials for cancer could slow progression of Parkinson's disease

Researchers at Johns Hopkins report they have identified a protein that enables a toxic natural aggregate to spread from cell to cell in a mammal's brain — and a way to block that protein's action.

29 Sep 2016

Tools of Undiagnosed Diseases Network help unravel mystery of rare genetic disease

The first patient was a mystery. Arriving at Duke six years ago at the age of three, the youngster had mild developmental delays and physical characteristics that included a large body and large head circumference.

29 Sep 2016

New 3-D printed biomaterial could be effective in treating children with bone defects

A Northwestern University research team has developed a 3-D printable ink that produces a synthetic bone implant that rapidly induces bone regeneration and growth. This hyperelastic "bone" material, whose shape can be easily customized, one day could be especially useful for the treatment of bone defects in children.

29 Sep 2016

Studies find environment plays major role in shaping immune system

Like fingerprints, immune systems vary from person to person. And although we all inherit a unique set of genes that help us respond to infections, recent studies have found that our history and environment—like where and with whom we live—are responsible for 60% to 80% of the differences between individual immune systems, while genetics account for the rest.

29 Sep 2016

Imran Noorani receives Brainlab Community Neurosurgery Abstract Award at 2016 CNS annual meeting

Imran Noorani MD, MRCS, of Cambridge, England, received the Brainlab Community Neurosurgery Abstract Award at the Congress of Neurological Surgeons Annual Meeting in San Diego.

28 Sep 2016

Researchers aim to discover new treatments for triple-negative breast cancer

The precision medicine approach involving DNA sequencing to pinpoint specific alterations that can be targeted with anti-cancer therapies is becoming an alternate treatment avenue for those with poor-responding cancers.

28 Sep 2016

Scientists identify molecule in liver cells that regulates release of fats into the bloodstream

ETH researchers have discovered a molecule in liver cells that controls the release of fat into the bloodstream. This "lock keeper" is present in large quantities in overweight people and leads indirectly to vascular narrowing.

28 Sep 2016

Researchers link RHOX gene mutations to infertility in men

The underlying cause of male infertility is unknown for 30 percent of cases. In a pair of new studies, researchers at University of California San Diego School of Medicine determined that the reproductive homeobox (RHOX) family of transcription factors — regulatory proteins that activate some genes and inactivate others — drive the development of stem cells in the testes in mice.

27 Sep 2016

Researchers identify process in the brains of mice that may explain repetitive actions in Rett patients

Three-year-old Naomi slaps her forehead a few times, bites her fingers and toddles across the doctor's office in her white and pink pajamas before turning her head into a door with a dull thud.

27 Sep 2016

Study suggests calorie-restricted diet can protect mice from abdominal aortic aneurysms

Mice placed on a low-calorie diet are less likely to develop abdominal aortic aneurysms, according to a new study in The Journal of Experimental Medicine.

26 Sep 2016

Are migraines genetic? An interview with Nick Furlotte

There's a big debate right now in the migraine community around the underlying cause of the disease. The question is whether it is vascular, and has something to do with our vessels, or whether it has to do with our neurons not functioning correctly or misfiring.

26 Sep 2016

Researchers identify, validate three distinct molecular subtypes of prostate cancer

In the largest study of its kind to date, researchers have identified and validated three distinct molecular subtypes of prostate cancer that correlate with distant metastasis-free survival and can assist in future research to determine how patients will respond to treatment, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

26 Sep 2016

KAUST researchers develop biocompatible nanostructures for use in gene delivery

A tiny therapeutic delivery system that can control the body’s ability to manufacture proteins has been developed by Saudi Arabia's King Abdullah University of Science and Technology (KAUST) researchers.

24 Sep 2016

DGIST researchers uncover mechanisms that control appetite during low glucose conditions in the brain

Researchers from Daegu Gyeongbuk Institute of Science and Technology (DGIST) in Korea have uncovered the mechanisms behind the enzyme that controls our appetite in response to low glucose availability in the brain.

24 Sep 2016

New global map shines light on genetic roots of diseases

A global genetic interaction map is revolutionizing how genes are being studied. A new study, involving University of Minnesota researchers, is no longer looking at genes as loners, but instead as a social network of the body, interacting in groups. The new approach may ultimately change our understanding of the genetic roots of diseases.

23 Sep 2016

Scientist uses stem cells derived from dental pulp to return hearing to deaf people

Deafness is a condition in which the hearing diminishes or disappears; currently there are few procedures to treat because it often is irreversible. Also, according to the World Health Organization (WHO), the disease globally affects 360 million people.

23 Sep 2016

Scientists manage to produce first molecular map of genes in the pancreas

Researchers at Karolinska Institutet have managed to produce the first molecular map of the genes that are active in the various cells of the human pancreas.

23 Sep 2016

Researchers receive grant to help develop stem cell therapy for glaucoma

Researchers from the University's Institute of Ageing and Chronic Disease have been awarded a pump-priming grant to help develop a stem cell therapy for glaucoma.

23 Sep 2016

DNA damage caused by smoking may last a lifetime

Results of a study published this week show that the effects of smoking on DNA are wide-reaching and some persist long after a person has stopped smoking. The information gained may help improve our understanding of smoking-related diseases.

23 Sep 2016

Precision medicine trial shows analysing person's DNA improves treatment options for cancer patients

A clinical trial for types of advanced cancer is the first of its kind to show that precision medicine - or tailoring treatment for individual people - can slow down the time it takes for a tumour to grow back, according to research presented at the Molecular Analysis for Personalised Therapy (MAP) conference, today (Friday).

23 Sep 2016

Genes News and Research

Immunotherapy already in clinical trials for cancer could slow progression of Parkinson's disease

Tools of Undiagnosed Diseases Network help unravel mystery of rare genetic disease

New 3-D printed biomaterial could be effective in treating children with bone defects

Studies find environment plays major role in shaping immune system

Imran Noorani receives Brainlab Community Neurosurgery Abstract Award at 2016 CNS annual meeting

Researchers aim to discover new treatments for triple-negative breast cancer

Scientists identify molecule in liver cells that regulates release of fats into the bloodstream

Researchers link RHOX gene mutations to infertility in men

Researchers identify process in the brains of mice that may explain repetitive actions in Rett patients

Study suggests calorie-restricted diet can protect mice from abdominal aortic aneurysms

Are migraines genetic? An interview with Nick Furlotte

Researchers identify, validate three distinct molecular subtypes of prostate cancer

KAUST researchers develop biocompatible nanostructures for use in gene delivery

DGIST researchers uncover mechanisms that control appetite during low glucose conditions in the brain

New global map shines light on genetic roots of diseases

Scientist uses stem cells derived from dental pulp to return hearing to deaf people

Scientists manage to produce first molecular map of genes in the pancreas

Researchers receive grant to help develop stem cell therapy for glaucoma

DNA damage caused by smoking may last a lifetime

Precision medicine trial shows analysing person's DNA improves treatment options for cancer patients

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