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Researchers use high-speed atomic force microscopy to explore the binding mechanism of cadherins

Cell, tissue, and organ structure is maintained by cell-cell adhesion molecules that connect opposing cells. Cadherins are a class of essential cell-cell adhesion molecules for tissue formation and integrity, and defects in cadherin function cause various diseases (e.g., cancer invasion).

19 Jul 2022

Six-country African study highlights the potential dangers of getting COVID-19 during pregnancy

A new study involving hospitalized women in six African countries from the University of Maryland School of Medicine's (UMSOM) Institute of Human Virology (IHV) showed that pregnant women with SARS-CoV-2, the virus that causes COVID-19, had double the risk of being admitted to the intensive care unit (ICU) and four-times the risk of dying in-hospital than pregnant women who did not have COVID-19.

19 Jul 2022

Should siRNA-based antivirals be added to the COVID toolbox?

A recent study reviewed the existing treatment modalities, including vaccines and antivirals, for SARS-CoV-2 infection.

19 Jul 2022

Researchers develop new SERS method for active capture of target molecules

Recently, a team led by Prof. Yang Liangbao from Hefei Institutes of Physical Science, Chinese Academy of Sciences used the nano-capillary pumping action to automatically capture the target molecules into a smaller gap and achieve highly sensitive Surface-Enhanced Raman Spectroscopy (SERS) detection by constructing a multilayer nanoparticle film to form a natural gap of less than 3 nm between the layers.

19 Jul 2022

Sex matters when it comes to immune responses to vaccines and viral infections

A review published in Frontiers in Aging analyzed the sex differences in the safety, effectiveness, and immunogenicity of influenza and COVID-19 vaccines in older individuals. It also analyzed the way sex brings about the modification of the impact of age-related factors on vaccination.

18 Jul 2022

Rice researchers use deactivated Cas9 proteins to synthetically trigger the transcription of genes

Rice University researchers have demonstrated that CRISPR-Cas9, increasingly famous as a gene-editing tool, can be employed in powerful additional ways in human cells.

18 Jul 2022

Researchers find link between brain protein and increased vulnerability to neurodegeneration in epilepsy patients

A team of Florida State University College of Medicine researchers has found a link between a specific protein in the brain and increased vulnerability to neurodegeneration for individuals with temporal lobe epilepsy (TLE).

18 Jul 2022

Research describes one of the ways the SARS-CoV-2 virus recruits cells to replicate

An article published in the journal Frontiers in Cellular and Infection Microbiology reports a study by researchers at the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil showing how a human protein interacts with a SARS-CoV-2 protein, and describing one of the ways the virus that causes COVID-19 recruits cells to replicate.

18 Jul 2022

DNA may act as nutritional source for E. coli

Findings of a new experiment could be helpful in understanding how DNA acts as a nutrient for gut bacteria, and its impact on the health of the host.

18 Jul 2022

Wistar scientists reveal a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence

Aging and age-related disorders pose a complex challenge to the biomedical research community. To better understand how senescence is regulated is of high significance to promote healthy aging and treat age-associated disorders.

18 Jul 2022

Study offers new insights into brain metastases in patients with melanoma

Brain metastasis is one of the most common causes of cancer-related deaths and occurs very frequently in patients with advanced melanoma.

18 Jul 2022

Caregivers for patients with multiple myeloma may suffer from anxiety and depression

Caregivers for patients with multiple myeloma may suffer from higher rates of anxiety and depression than patients themselves, according to a new study published today in Blood Advances.

18 Jul 2022

Alternative therapy based on S100A9 protein improves metabolism of insulin-dependent diabetics

People with a severe form of diabetes, where the beta cells of the pancreas do not produce or no longer produce enough insulin, have no choice but to inject themselves regularly with artificial insulin in order to survive.

18 Jul 2022

Scientists develop an improved pharmaceutical drug for the treatment of atrial fibrillation

Scientists from the National University of Singapore Department of Pharmacy have developed an improved pharmaceutical drug for the treatment of the most common heart rhythm disturbance – atrial fibrillation (AF).

18 Jul 2022

What is the impact of lower COVID-19 vaccine doses in younger cohorts?

A new study evaluated the impact of the lower SARS-CoV-2 vaccine dosages in younger populations.

18 Jul 2022

Analyzing whether SARS-CoV-2 nucleocapsid and spike proteins stimulate dendritic or γδ T cells

Researchers showed that the SARS-CoV-2 nucleocapsid (N) and spike (S) proteins did not activate γδ T cells and dendritic cells (DCs).

18 Jul 2022

Nitazoxanide drug found to be a potent inhibitor of several human coronaviruses

Researchers evaluated the activity of nitazoxanide against human coronaviruses (HCoVs).

18 Jul 2022

Scientists evaluate immunostimulatory glycolipid against SARS-CoV-2 infection

A new study showed that 7DW8-5, an immunostimulatory glycolipid impeded three respiratory viral infections, including SARS-CoV-2, in vivo.

18 Jul 2022

The impact of glucocorticoid therapy on immune responses to COVID-19 vaccination or infection in rituximab-treated patients with autoimmune disorders

Researchers examined immune reactions to SARS-CoV-2)among B cell-depleted autoimmune patients who concomitantly administered glucocorticoids.

18 Jul 2022

Future SARS-CoV-2 vaccines could hijack commensal bacteria in the gut–lung axis to confer immunity

Researchers screened bacterial mucosal vaccine vectors from 2015 to the present to identify a promising candidate to present SARS-CoV-2 spike protein or its fragments.

18 Jul 2022

Cell News and Research

Researchers use high-speed atomic force microscopy to explore the binding mechanism of cadherins

Six-country African study highlights the potential dangers of getting COVID-19 during pregnancy

Should siRNA-based antivirals be added to the COVID toolbox?

Researchers develop new SERS method for active capture of target molecules

Sex matters when it comes to immune responses to vaccines and viral infections

Rice researchers use deactivated Cas9 proteins to synthetically trigger the transcription of genes

Researchers find link between brain protein and increased vulnerability to neurodegeneration in epilepsy patients

Research describes one of the ways the SARS-CoV-2 virus recruits cells to replicate

DNA may act as nutritional source for E. coli

Wistar scientists reveal a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence

Study offers new insights into brain metastases in patients with melanoma

Caregivers for patients with multiple myeloma may suffer from anxiety and depression

Alternative therapy based on S100A9 protein improves metabolism of insulin-dependent diabetics

Scientists develop an improved pharmaceutical drug for the treatment of atrial fibrillation

What is the impact of lower COVID-19 vaccine doses in younger cohorts?

Analyzing whether SARS-CoV-2 nucleocapsid and spike proteins stimulate dendritic or γδ T cells

Nitazoxanide drug found to be a potent inhibitor of several human coronaviruses

Scientists evaluate immunostimulatory glycolipid against SARS-CoV-2 infection

The impact of glucocorticoid therapy on immune responses to COVID-19 vaccination or infection in rituximab-treated patients with autoimmune disorders

Future SARS-CoV-2 vaccines could hijack commensal bacteria in the gut–lung axis to confer immunity

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